Results 111 to 120 of about 267,597 (244)

Molecular cancer prevention: Intercepting disease

Molecular Oncology, EarlyView.
Oncological practice must evolve, from treating established tumours to proactive cancer interception before clinical manifestation. This will require mechanistic insight into tumour initiation, validated biomarkers of early disease development and redesigned clinical trials, enabling cancer interception to become a core pillar of oncology with the ...
Charlotte Grieco, Tej Pandya, Charles Swanton   +2 more
wiley   +1 more source

Antimicrobial Stewardship Program: actions and education in Brazilian pediatric intensive care units. [PDF]

Rev Lat Am Enfermagem
Krummenauer EC, Assis MP, Gonçalves MRS, Costa MMM, Menezes RM, Motta FA, Renner JDP, Carneiro M.   +7 more
europepmc   +1 more source

DNA methylation and expression of MAPRE3 affect overall survival of early‐stage non‐small cell lung cancer patients

Molecular Oncology, EarlyView.
Both cg12821679MAPRE3 methylation and MAPRE3 expression are significantly associated with overall survival (OS) of non‐small cell lung cancer. Meanwhile, MAPRE3 expression significantly modified the effect of smoking cessation on OS. Smoking cessation benefits OS merely for patients with high MAPRE3 expression.
Chao Chen, Jiancheng Cheng, Ruili Hou, Xiaoyuan Zheng, Li Su, Maria Moksnes Bjaanæs, Anna Karlsson, Maria Planck, Johan Staaf, Åslaug Helland, Manel Esteller, David C. Christiani, Feng Chen, Xiaofei Cao, Ruyang Zhang   +14 more
wiley   +1 more source

[Cuauhtémoc in the defense of Mexico-Tenochtitlan: The work of Luis Ortiz Monasterio in Oaxtepec]. [PDF]

Rev Med Inst Mex Seguro Soc
Rivas-Ruiz R.
europepmc   +1 more source

Circulating tumor cell viability during and after radiotherapy mirrors treatment response in cancer patients

Molecular Oncology, EarlyView.
Radiotherapy (RT) response depends on the DNA repair capacity of tumor and host cells. We show that circulating tumor cell (CTC) counts and apoptosis rates before and after RT predict treatment response and outcome, which can be accessed via easily accessible liquid biopsy approaches. Created in BioRender. Wikman, H.
Yvonne Goy, Jana Löptien, Cornelia Coith, Afroditi Nanou, Katharina Hintelmann, Pinnschmidt Hans, Cordula Petersen, Klaus Pantel, Sabine Riethdorf, Kerstin Borgmann, Harriet Wikman   +10 more
wiley   +1 more source

Current status and factors influencing clinical nurses' attitudes toward information security: a cross-sectional survey. [PDF]

Rev Esc Enferm USP
Xue B, Yurui X, Shuping G, Shuangdui J, Donglian Z, Fuzhen M, Changqi Y.   +6 more
europepmc   +1 more source

Overview of molecular signatures of senescence and associated resources: pros and cons

FEBS Open Bio, EarlyView.
Cells can enter a stress response state termed cellular senescence that is involved in various diseases and aging. Detecting these cells is challenging due to the lack of universal biomarkers. This review presents the current state of senescence identification, from biomarkers to molecular signatures, compares tools and approaches, and highlights ...
Orestis A. Ntintas, Sylvia Vagena, Pavlos Pantelis, Giorgos Theocharous, Russel Petty, Konstantinos Evangelou, Vassilis G. Gorgoulis   +6 more
wiley   +1 more source

[Impact of increased meeting frequency of the antimicrobial stewardship program team on indicators of the hospital use of antimicrobial agents based on consumption]. [PDF]

Rev Esp Quimioter
Zas-García MI, Fernández-Carreira JM, González-Fernández D, Castelo-Alvárez E, Rubio-Sanz J, Álvarez-Pérez M, Blanco-Suárez A, Rodríguez-Prida J, Rubio-Alfonso T.   +8 more
europepmc   +1 more source

SIRT4 positively regulates autophagy via ULK1, but independently of HDAC6 and OPA1

FEBS Open Bio, EarlyView.
Cells expressing SIRT4 (H161Y), a catalytically inactive mutant of the sirtuin SIRT4, fail to upregulate LC3B‐II and exhibit a reduced autophagic flux under stress conditions. Interestingly, SIRT4(H161Y) promotes phosphorylation of ULK1 at S638 and S758 that are associated with inhibition of autophagy initiation.
Isabell Lehmkuhl, Khawar Amin, Lydia Gabriel, Nils Hampel, Afshin Iram, Julia Hesse, Constanze Wiek, Jasmin Thuy Vy Nguyen, Helmut Hanenberg, Jürgen Scheller, M. Reza Ahmadian, Björn Stork, Doreen M. Floss, Roland P. Piekorz   +13 more
wiley   +1 more source

Beyond the knife: HDR plesiotherapy brings precision to atypical fibroxanthoma. [PDF]

Ecancermedicalscience
Saiz C, Montero A, López M, Zambrana B, Alvarez B, Valero J, Ciervide R, Hernando O, Garcia-Aranda M, Sanchez E, Alonso L, Chen-Zhao X, Alonso R, Rubio C.   +13 more
europepmc   +1 more source