Results 61 to 70 of about 1,685,245 (302)

Understanding child neglect [PDF]

, 2014
Child neglect is one of the most common forms of maltreatment. Neglect is a topic that encompasses complex issues, many of which are also emerging research areas. This paper aims to provide a broad overview of these issues in relation to current thinking
Debbie Scott
core  

MITF maintains genome stability in nonmelanocyte lineages

Molecular Oncology, EarlyView.
MITF is essential for melanocyte survival and acts as an oncogene in 10%–20% of melanomas. We show that MITF depletion causes genome instability in nonmelanocytic cells, leading to LATS2‐mediated P53 activation, cell cycle arrest, and apoptosis. This study highlights the role of MITF as a genome maintenance factor beyond the melanocyte lineage. Created
Drifa H. Gudmundsdottir, Adrián López García de Lomana, Thejus B. Venkatesh, Kritika Kirty, Snaevar Sigurdsson, Linda Vidarsdottir, Ramile Dilshat, Erla Sveinbjornsdottir, Snaedis Ragnarsdottir, Daniel H Magnusson, Maria R. Bustos, Eirikur Steingrimsson, Thorkell Gudjonsson, Stefan Sigurdsson   +13 more
wiley   +1 more source

Reflections of a Mi’kmaq social worker on a quarter of a century work in First Nations child welfare

, 2007
First Nations people would argue that the ‘Sixties Scoop’ of removing their children from their homes and culture never ended. First Nations children entering ‘care’ of child welfare agencies has increased significantly since the 1960s and 1970s. Storying
MacDonald, Nancy, MacDonald, Judy
core   +1 more source

Oncogenic DMTF1β promotes cancer cell motility by regulating autophagy through ULK1 stabilization

Molecular Oncology, EarlyView.
In the current study, we demonstrate that the oncogene DMTF1β regulates ULK1 stability by reducing its proteasomal degradation in cancer cells. This stabilization enables ULK1 to induce autophagy, which in turn facilitates cancer cell migration. Consequently, reduced DMTF1β levels lead to decreased autophagy and impaired cancer cell migration.
Jun Xu, Nicolas J. Niklaus, Anna M. Schläfli, Igor Tokarchuk, Magali Humbert, Federico La Manna, Bich Vu, David Maul, Ramin Radpour, Marianna Kruithof‐de Julio, Inti Zlobec, Jörn Dengjel, Bruce E. Torbett, Mario P. Tschan   +13 more
wiley   +1 more source

Relation of Nursing Support From Parents With Meeting the Needs of Mothers of Children Hospitalized in Besat Hospital, Hamadan

مراقبت پرستاری و مامایی ابن سینا, 2018
Introduction: hospitalization of a child is one of the main causes of parent’s anxiety. Regarding the importance of providing family-based care, it is necessary for nurses to support and understand parents’ needs to provide them.
Saeideh Almasi, Fatemeh Cheraghi, Ghodratollah Roshanaei, Arash Khalili, Maryam Dehghani   +4 more
doaj  

Cost-effectiveness of rotavirus vaccination in Turkey

Journal of Microbiology, Immunology and Infection, 2017
Background/Purpose: Cost-effectiveness studies about rotavirus (RV) vaccination programs were performed in many countries due to the severe economic burden of RV infections.
Tulin Koksal, Ahmet Zulfikar Akelma, Ali Osman Koksal, Irem Kutukoglu, Osman Ozdemir, Cigdem Nuket Yuksel, Davut Bozkaya, Ferhat Catal, Sinan Sari   +8 more
doaj   +1 more source

Morbilliform Eruptions in the Hospitalized Child. [PDF]

Dermatol Clin, 2022
Haber JS, Cipriano SD, Oza VS.
europepmc   +1 more source

In vitro and in silico modelling of ROS1‐positive non‐small cell lung cancer reveals fusion‐dependent tyrosine kinase inhibitor responses

Molecular Oncology, EarlyView.
Drug resistance limits treatment success in a subset of lung cancers driven by ROS1 gene alterations. Using patient‐derived cells and computer simulations, we studied three key mutations and how they affect five targeted drugs. The mutations reduced drug effectiveness in different ways by altering protein structure and behavior.
Farhan Ul Haq, Marc Terrones, Felicia Rodrigues Fortes, Anne Schepers, Alessia Denis, Christophe Deben, Ken Op de Beeck, Guy Van Camp, Geert Vandeweyer   +8 more
wiley   +1 more source

Estimation of the national disease burden of influenza-associated severe acute respiratory illness in Kenya and Guatemala : a novel methodology [PDF]

, 2013
Background: Knowing the national disease burden of severe influenza in low-income countries can inform policy decisions around influenza treatment and prevention.
Njuguna Henry, Mott, Joshua A., Kim A. Lindblade (265496), Henry Njuguna, Marc-Alain Widdowson, Mwanajuma Ngama (132330), Sonja J Olsen, Kim A Lindblade, Katz Mark A., Sidi Kazungu (382842), Joshua A. Mott (382843), Summers Aimee, McCracken John, Wences Arvelo, Sammy Khagayi, John McCracken, Khagayi Sammy, Kazungu Sidi, Aimee Summers (382838), Fuller James A., Marc-Alain Widdowson (123352), D. James Nokes (68994), Daniel R. Feikin (153640), Njuguna, Henry, Fuller, James A., Ngama, Mwanajuma, Daniel R Feikin, Joshua A Mott, Emukule Gideon, Sonja J. Olsen (226208), McCracken, John, Mark A. Katz (310324), Wences Arvelo (358137), Kazungu, Sidi, Mark A Katz, Nivaldo Linares-Perez, Nivaldo Linares-Perez (382840), Nokes D. James, Katz, Mark A., Mott Joshua A., Arvelo Wences, Sidi Kazungu, Olsen Sonja J., Summers, Aimee, Feikin, Daniel R., Olsen, Sonja J., Mwanajuma Ngama, Henry Njuguna (319757), Lindblade Kim A., James A Fuller, John McCracken (382841), Gideon Emukule, James A. Fuller (382837), Linares-Perez Nivaldo, Nokes, D. James, Arvelo, Wences, Emukule, Gideon, Gideon Emukule (336782), Widdowson Marc-Alain, D James Nokes, Linares-Perez, Nivaldo, Khagayi, Sammy, Ngama Mwanajuma, Aimee Summers, Sammy Khagayi (382839), Widdowson, Marc-Alain, Lindblade, Kim A., Feikin Daniel R.   +67 more
core   +1 more source

Simultaneous detection of enterovirus-D68 and vaccine-related poliovirus 3 in the stool samples of a 5-month hospitalized child with acute respiratory disease: A case report. [PDF]

Biosaf Health, 2023
Su W, Zeng Q, Geng J, Liu J, Xie H, Li K, Qin P, Xie C, Di B.   +8 more
europepmc   +1 more source