Results 71 to 80 of about 1,685,245 (302)

Translating whole‐genome doubling into precision medicine in cancer

Molecular Oncology, EarlyView.
Whole‐genome doubling creates a WGD‐positive tumor state characterized by persistent chromosomal instability, karyotypic diversification, and cellular stress. These same biological pressures drive aggressive tumor evolution while exposing therapeutic vulnerabilities, providing a rationale for WGD‐informed precision medicine. Whole‐genome doubling (WGD)
Sejung Lee, Junghyeok Lim, Jinhyuk Bhin
wiley   +1 more source

Atenção pré-natal na rede básica: uma avaliação da estrutura e do processo

Cadernos de Saúde Pública
Realizou-se estudo transversal descritivo e auditoria de registros médicos para avaliar a estrutura e o processo de atendimento pré-natal nas unidades de atenção primária à saúde em Pelotas, Sul do Brasil.
Denise Silva da Silveira, Iná Silva dos Santos, Juvenal Soares Dias da Costa   +2 more
doaj  

Intrapatient tumour heterogeneity and clonal evolution in an autopsy study of metastatic salivary gland cancer

Molecular Oncology, EarlyView.
Tumour heterogeneity and clonal evolution of metastatic salivary gland cancer were evaluated in two patients with adenoid carcinoma and one patient with myoepithelial carcinoma. Radiology‐guided autopsy enabled multi‐region sampling (total samples n = 149), followed by whole‐genome sequencing and phylogenetic reconstruction (17 tumour samples, 4–7 per ...
Gerben Lassche, Niels J. van Ruitenbeek, Charlotte Adang, Luke O'Gorman, Pui Yuen Lee, Willemijn M. Klein, Adriana C. H. van Engen‐van Grunsven, Jack A. Schalken, Sander Bervoets, Gerald W. Verhaegh, Carla M. L. van Herpen   +10 more
wiley   +1 more source

Child Support Services Handbook

, 2013
application/pdfThe Kansas Child Support Services (CSS) program helps children receive the financial support necessary for their growth and development.
Kansas Child Support Services.
core  

Care for hospitalized children undergoing institutionalization in light of the psychodynamics of work [PDF]

Revista Brasileira de Enfermagem
Objectives: to analyze the factors of pleasure and distress of nurses in the care of hospitalized children undergoing institutionalization in a pediatric unit.
Daniela Giotti da Silva, Maria de Lourdes Custódio Duarte, Eduarda Paza Dias, Alessandra Porto d’Ávila, Karolaine Aparecida Borba Lopes   +4 more
doaj   +1 more source

Effects of IGFBP4 deficiency on human preadipocyte proliferation and differentiation through the IGF1R/AKT pathway

FEBS Open Bio, EarlyView.
IGFBP4 knockdown (KD) impairs preadipocyte proliferation and is associated with IGF1R protein downregulation and attenuated AKT phosphorylation. The mechanisms by which IGFBP4 KD influences the IGF1R/AKT signaling pathway involve newly synthesized proteins and lysosomal degradation pathways. Created in BioRender.
Yujia Guo, Sandy Richter, Christoph Bach, Wieland Kiess, Anna Kirstein, Diana Le Duc, Antje Garten   +6 more
wiley   +1 more source

CFD 390 - Hospitalized Child

, 2014
Psychosocial needs of hospitalized child. Best practices for working with children and their families, and application of Patient Care vs. Family Centered Care.
Beltran, Lisa
core  

Effect of playing on anxiety of hospitalized school age children

Journal of Holistic Nursing and Midwifery, 2005
Introduction: Anxiety is one of the most common reactions to stressors and ‎hospitalized children confront it and playing is a priority care to reduce stress.‎ Objective: The present study was conducted to determine the effect of playing on the &
, yasaman yaghoobi, zahra shafipour, zahra atrkar roushan, jafar modaber nia   +4 more
doaj  

Clinical and microbiological evaluation of dental plaque on topical application of olive oil, olive oil with 35% Curcuma zedoaria, and olive oil with 30% Azadirachta indica in hospitalized children: A randomized control trial

Journal of Indian Society of Pedodontics and Preventive Dentistry
Background: Hospitalized children find difficulty in performing regular oral hygiene procedures. In such cases, direct application of herbal oils such as olive oil, Azadirachta indica (AI) (neem), and Curcuma zedoaria (CZ) (white turmeric) as antiplaque ...
Anshula Deshpande, Simron Baishya, Sneha Dori, Medha Wadhwa, Khushali Shah   +4 more
doaj   +1 more source

Pathways and pitfalls: a qualitative study of student experiences in biomedical science education

FEBS Open Bio, EarlyView.
Biomedical science students from underrepresented backgrounds face barriers including financial strain, disrupted laboratory access and cultural exclusion. Peer networks provide vital support when institutional systems are difficult to navigate. To create inclusive learning environments and achieve academic success, educators should blend active, hands‐
Olivia J. Russell, Cassy Ross, Panagiota S. Filippou, Bruno Silvester Lopes, Dominic Gilchrist, Paul Dean, Kamar Ameen‐Ali, Tora K. Smulders‐Srinivasan, Ahmad A. Khundakar   +8 more
wiley   +1 more source