Results 101 to 110 of about 3,835,123 (287)

Establishment of a humanized SCA2 mouse model carrying a CAA disruption preventing CAG repeat expansion in pathogenic genes

open access: yesAnimal Models and Experimental Medicine, EarlyView.
In this study, we established a mouse model in which CAG repeats do not undergo microsatellite instability (MSI) across generations. A humanized ATXN2 cDNA with four CAA interruptions within 73 CAG expansions was inserted into the Rosa26 locus of C57BL/6J mice. At the same time, a 23 CAG control mouse model was also generated.
Yao Zhang   +9 more
wiley   +1 more source

Psychiatric Disorders and Trends in Resource Use in Pediatric Hospitals

open access: yesPediatrics, 2016
B. Zima   +5 more
semanticscholar   +1 more source

AI in Neurology: Everything, Everywhere, All at Once Part 1: Principles and Practice

open access: yesAnnals of Neurology, EarlyView.
Artificial intelligence (AI) is rapidly transforming healthcare, yet it often remains opaque to clinicians, scientists, and patients alike. This review, part 1 of a 3‐part series, provides neurologists and neuroscientists with a foundational understanding of AI's key concepts, terminology, and applications.
Matthew Rizzo, Jeffrey D. Dawson
wiley   +1 more source

AI in Neurology: Everything, Everywhere, All at Once Part 3: Surveillance, Synthesis, Simulation, and Systems

open access: yesAnnals of Neurology, EarlyView.
This final part 3 review builds on the practical applications discussed in part 2 and explores how artificial intelligence (AI) is transforming data management, neurological education, and neurological care across large healthcare networks and datasets. The review also highlights AI's role in real‐world and synthetic data, digital twins, and innovative
Matthew Rizzo
wiley   +1 more source

Predictive factors of mental health and psychiatric nursing competencies of professional nurses working in psychiatric hospitals, southern Thailand

open access: yesJournal of Health Science and Medical Research (JHSMR), 2007
Objective: To examine and analyze the factors that predict mental health and psychiatric nursing competencies of professional nurses in psychiatric hospitals, southern Thailand.
B Petcharat   +2 more
doaj  

Neuroimaging Biomarkers for Friedreich Ataxia: A Cross‐Sectional Analysis of the TRACK‐FA Study

open access: yesAnnals of Neurology, EarlyView.
Objective We aimed to quantify differences in the brain and spinal cord between Friedreich ataxia and controls, stratified by age and disease stage, including for the first time in young children. Methods TRACK‐FA is the largest prospective, longitudinal, multi‐modal neuroimaging study in Friedreich ataxia to date.
Nellie Georgiou‐Karistianis   +33 more
wiley   +1 more source

Comparison of Religious Teaching with Muscle Relaxation Methods on Anxiety Patients

open access: yesCaspian Journal of Neurological Sciences, 2019
Background: Anxiety in psychiatric patients is more prevalent than the general population. Non-pharmacological methods for the treatment of anxiety are beneficial to the health of the patient, but it is not clear which of these approaches are more ...
Fateme Attar Ghasbe   +4 more
doaj  

Disturbing findings about the risk of suicide and psychiatric hospitals

open access: yesSocial Psychiatry and Psychiatric Epidemiology, 2014
M. Large, C. Ryan
semanticscholar   +1 more source

The Spectrum of Neurologic Phenotypes Associated With NUS1 Pathogenic Variants: A Comprehensive Case Series

open access: yesAnnals of Neurology, EarlyView.
Objective A growing body of evidence indicates a strong genetic overlap between developmental and epileptic encephalopathies (DEEs) and movement disorders. De novo loss‐of‐function variants in NUS1 have been recently identified in DEE cases. Herein, we report a large cohort of cases with pathogenic NUS1 variants and describe their clinical presentation
Sarah M. Brooker   +79 more
wiley   +1 more source

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