Results 71 to 80 of about 9,187,129 (361)

Low-value care in Australian public hospitals: prevalence and trends over time

BMJ Quality & Safety, 2018
Objective To examine 27 low-value procedures, as defined by international recommendations, in New South Wales public hospitals. Design Analysis of admitted patient data for financial years 2010–2011 to 2016–2017.
T. Badgery-Parker, Sallie-Anne Pearson, K. Chalmers, J. Brett, I. Scott, S. Dunn, Neville Onley, A. Elshaug   +7 more
semanticscholar   +1 more source

Exploration of heterogeneity and recurrence signatures in hepatocellular carcinoma

Molecular Oncology, EarlyView.
This study leveraged public datasets and integrative bioinformatic analysis to dissect malignant cell heterogeneity between relapsed and primary HCC, focusing on intercellular communication, differentiation status, metabolic activity, and transcriptomic profiles.
Wen‐Jing Wu, Jianchao Wang, Fuqing Chen, Xuefeng Wang, Bin Lan, Ruyi Fu, Hong Wen, Fangfang Chen, Wei Hong, Tian‐Yu Tang, Ying He, Gang Chen, Jianyin Zhou, Hai‐Long Piao, Di Chen, Shu‐Yong Lin   +15 more
wiley   +1 more source

DESARROLLO DE UN PROGRAMA PILOTO DE FARMACOVIGILANCIA EN EL HOSPITAL SAN JUAN DE DIOS DE ZIPAQUIRÁ DEVELOPMENT OF A PHARMACOVIGILANCE PILOT PROGRAM IN THE SAN JUAN DE DIOS HOSPITAL OF ZIPAQUIRA

Revista U.D.C.A Actualidad & Divulgación Científica, 2008
Los programas hospitalarios de farmacovigilancia son indispensables para la consolidación de un programa nacional y para el mejoramiento continuo de la calidad de la atención hospitalaria.
Gabriel Tribiño E.
doaj  

The atypical KRASQ22K mutation directs TGF‐β response towards partial epithelial‐to‐mesenchymal transition in patient‐derived colorectal cancer tumoroids

Molecular Oncology, EarlyView.
TGF‐β has a complex role in cancer, exhibiting both tumor‐suppressive and tumor‐promoting properties. Using a series of differentiated tumoroids, derived from different stages and mutational background of colorectal cancer patients, we replicate this duality of TGF‐β in vitro. Notably, the atypical but highly aggressive KRASQ22K mutation rendered early‐
Theresia Mair, Philip König, Milena Mijović, Jessica Kalla, Anil Baskan, Loan Tran, Kristina Draganić, Pedro Morata Saldaña, Carlos Uziel Pérez Malla, Janette Pfneissl, Andreas Tiefenbacher, Julijan Kabiljo, Velina S. Atanasova, Lisa Wozelka‐Oltjan, Leonhard Müllauer, Michael Bergmann, Raheleh Sheibani‐Tezerji, Gerda Egger   +17 more
wiley   +1 more source

Baseline assessment of patient safety culture in public hospitals in Kuwait

BMC Health Services Research, 2018
BackgroundConducting patient safety culture assessments can provide hospitals with information on how structures and processes within their system can impact patient outcomes.
H. Ali, Samaa Z Ibrahem, Buthaina Al Mudaf, Talal Al Fadalah, Diana Jamal, F. El-Jardali   +5 more
semanticscholar   +1 more source

A large‐scale retrospective study in metastatic breast cancer patients using circulating tumour DNA and machine learning to predict treatment outcome and progression‐free survival

Molecular Oncology, EarlyView.
There is an unmet need in metastatic breast cancer patients to monitor therapy response in real time. In this study, we show how a noninvasive and affordable strategy based on sequencing of plasma samples with longitudinal tracking of tumour fraction paired with a statistical model provides valuable information on treatment response in advance of the ...
Emma J. Beddowes, Mario Ortega Duran, Solon Karapanagiotis, Alistair Martin, Meiling Gao, Riccardo Masina, Ramona Woitek, James Tanner, Fleur Tippin, Justine Kane, Jonathan Lay, Anja Brouwer, Stephen‐John Sammut, Suet‐Feung Chin, Davina Gale, Dana W. Y. Tsui, Sarah‐Jane Dawson, Nitzan Rosenfeld, Maurizio Callari, Oscar M. Rueda, Carlos Caldas   +20 more
wiley   +1 more source

Record-keeping: Challenges experienced by nurses in selected public hospitals

Curationis, 2018
Background Patients’ records provide a trace of care processes that have occurred and are further used as communication amongst nurses for continued management of patients.
T. E. Mutshatshi, T. Mothiba, P. Mamogobo, M. Mbombi   +3 more
semanticscholar   +1 more source

Forecasting hospital demand during COVID-19 pandemic outbreaks [PDF]

arXiv, 2020
We present a compartmental SEIRD model aimed at forecasting hospital occupancy in metropolitan areas during the current COVID-19 outbreak. The model features asymptomatic and symptomatic infections with detailed hospital dynamics. We model explicitly branching probabilities and non exponential residence times in each latent and infected compartments ...
arxiv  

Determinants of hypertensive crisis among hypertensive patients at adult emergency departments of public hospitals in Addis Ababa, Ethiopia, 2021: a case–control study

International Journal of Emergency Medicine, 2023
Background Hypertension (HTN) is a major global health problem that affects approximately 1.13 billion people worldwide, and 1–2% of this population has hypertensive crisis.
Hailemariam Gezie, Aklilu Azazh, Birhanu Melaku, Habtam Gelaye   +3 more
doaj   +1 more source

ShcD adaptor protein drives invasion of triple negative breast cancer cells by aberrant activation of EGFR signaling

Molecular Oncology, EarlyView.
We identified adaptor protein ShcD as upregulated in triple‐negative breast cancer and found its expression to be correlated with reduced patient survival and increased invasion in cell models. Using a proteomic screen, we identified novel ShcD binding partners involved in EGFR signaling pathways.
Hayley R. Lau, Hayley S. Smith, Begüm Alural, Claire E. Martin, Laura A. New, Manali Tilak, Sara L. Banerjee, Hannah N. Robeson, Nicolas Bisson, Anne‐Claude Gingras, Jasmin Lalonde, Nina Jones   +11 more
wiley   +1 more source