Results 71 to 80 of about 584,955 (263)

LDAcoop: Integrating non‐linear population dynamics into the analysis of clonogenic growth in vitro

Molecular Oncology, EarlyView.
Limiting dilution assays (LDAs) quantify clonogenic growth by seeding serial dilutions of cells and scoring wells for colony formation. The fraction of negative wells is plotted against cells seeded and analyzed using the non‐linear modeling of LDAcoop.
Nikko Brix, Daniel Samaga, Katharina Gehr, Benedek Dankó, Mohamed Schumann, Guido Drexler, Ahmed Alnatsha, Georg Beyer, Ujjwal Mahajan, Martin Selmansberger, Julia Mayerle, Claus Belka, Horst Zitzelsberger, Kirsten Lauber   +13 more
wiley   +1 more source

Bureauphobia in Public Hospitals of Qom, Iran

Majallah-i Dānishgāh-i ̒Ulūm-i Pizishkī-i Qum, 2022
Background and Objectives: Bureauphobia in the public sector doubts the direct effect of good services on people’s trust. Addressing bureauphobia in public hospitals can be an attempt for increasing trust in the public sector, in addition to improving ...
Ahmad Rahbar, Khadijeh Alipour Nodoushan, Roghayeh Babaei Arbatan, Seyed Mohammad Sajadi, Hossein Azari   +4 more
doaj  

Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin

Molecular Oncology, EarlyView.
The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla, Jan Kosla, Magdalena Prechova, Lukas Frick, Patricia Bortel, Yasmin Borutzki, Andrea Bileck, Christopher Gerner, Samuel M. Meier‐Menches, Selma Osmanagic‐Myers, Martin Gregor   +10 more
wiley   +1 more source

PRODUCTIVITY INDICATORS IN PUBLIC HOSPITALS

Visión de Futuro, 2017
The public hospital is the great receiver par excellence in what refers to traumatized, but that excellence seems to fade in the face of poor building conditions and inefficient processes, product, perhaps, of the imposing current message that states ...
Medina, Orlando Francisco, De Marco, Myriam Lilian Cecilia   +1 more
doaj  

Data linkage studies of primary care utilisation after release from prison: a scoping review

BMC Primary Care
Background Primary care plays a central role in most, if not all, health care systems including the care of vulnerable populations such as people who have been incarcerated.
Janine A. Cooper, Siobhán Murphy, Richard Kirk, Dermot O’Reilly, Michael Donnelly   +4 more
doaj   +1 more source

Examining Public Relations Practices Used in Hospitals Through Web Pages: Comparison of Public and Private Hospitals

Sakarya Üniversitesi Holistik Sağlık Dergisi
Objective: The main purpose of this study is to examine the public relations practices used in hospitals through web pages.Method: Public relations practice studies in the literature have been examined and a scale has been developed by using the ...
Kahraman Çatı, Murat Bayat, Şükran Karaca, Mehmet Öney, Mustafa Polat, Yusuf Öcel   +5 more
doaj   +1 more source

Recurrent cancer‐associated ERBB4 mutations are transforming and confer resistance to targeted therapies

Molecular Oncology, EarlyView.
We show that the majority of the 18 analyzed recurrent cancer‐associated ERBB4 mutations are transforming. The most potent mutations are activating, co‐operate with other ERBB receptors, and are sensitive to pan‐ERBB inhibitors. Activating ERBB4 mutations also promote therapy resistance in EGFR‐mutant lung cancer.
Veera K. Ojala, Sini Ahonen, Sara Peltola, Aura Tuohisto‐Kokko, Olaya Esparta, Peppi Suominen, Anne Jokilammi, Iman Farahani, Deepankar Chakroborty, Nikol Dibus, Steffen Boettcher, Tomi T. Airenne, Mark S. Johnson, Lisa D. Eli, Klaus Elenius, Kari J. Kurppa   +15 more
wiley   +1 more source

Organizational culture of selected hospitals of Tehran city

بیمارستان, 2017
Background: Organizational culture has a crucial role in hospitals’ productivity. The success or failure of strategies and plans in organisational change depend on organizational culture.
Mobin Sokhanvar, Alimohammad Mosadeghrad
doaj  

Crucial parameters for precise copy number variation detection in formalin‐fixed paraffin‐embedded solid cancer samples

Molecular Oncology, EarlyView.
This study shows that copy number variations (CNVs) can be reliably detected in formalin‐fixed paraffin‐embedded (FFPE) solid cancer samples using ultra‐low‐pass whole‐genome sequencing, provided that key (pre)‐analytical parameters are optimized.
Hanne Goris, Vasiliki Siozopoulou, Léon C van Kempen, Anne Sieben, Ella Roelant, Stig Hellemans, Elyne Backx, Laure Sorber, Koen De Winne, Senada Koljenović, Karen Zwaenepoel   +10 more
wiley   +1 more source

Tumor mutational burden as a determinant of metastatic dissemination patterns

Molecular Oncology, EarlyView.
This study performed a comprehensive analysis of genomic data to elucidate whether metastasis in certain organs share genetic characteristics regardless of cancer type. No robust mutational patterns were identified across different metastatic locations and cancer types.
Eduardo Candeal, Andrea Moreno‐Manuel, Miguel Salvadó‐Pertierra, Cristina Santos‐Vivas, Rebeca Sanz‐Pamplona   +4 more
wiley   +1 more source