Results 161 to 170 of about 78,496,881 (308)

Identification of (20R)‐protopanaxadiol from Panax ginseng as a novel anti‐SARS‐CoV‐2 compound

FEBS Open Bio, EarlyView.
We established a noninfectious BAC‐based SARS‐CoV‐2 replicon that enables antiviral screening under BSL‐2 conditions. Using this platform, we screened 373 food‐derived compounds and identified (20R)‐protopanaxadiol from Panax ginseng as a novel inhibitor of SARS‐CoV‐2 RNA replication, highlighting the value of safe replicon systems for antiviral ...
Midori Takeda, Natsue Maezono, Rina Uchikoshi, Nobuyuki Kato, Masanori Ikeda   +4 more
wiley   +1 more source

University Hospitals General Staff Meeting, February 11, 1932

, 1932
University of Minnesota. University of Minnesota Hospitals. (1932). University Hospitals General Staff Meeting, February 11, 1932.
University of Minnesota. University of Minnesota Hospitals
core  

Effects of public hospital clerkship in rural and underserved areas in South Korea on medical students' perceptions and career intentions: a pre-post study. [PDF]

Korean J Med Educ
Kim S, Im S, Lee W, Lee SH, Jeong HJ, Lee SY, Lee JT, Seo JH.   +7 more
europepmc   +1 more source

GelMA‐based 3D spheroids recapitulate transcriptomic and functional hallmarks of myeloid sarcoma

FEBS Open Bio, EarlyView.
GelMA 5% hydrogels support the formation of myeloid leukemia spheroids that recapitulate MS‐specific features, including G1 arrest, apoptosis, and ECM‐driven transcriptomic reprogramming. The 3D model mimicked soft‐tissue‐like stiffness and oxygen conditions, and transcriptomic convergence with primary MS samples confirmed its utility as a preclinical ...
Nicolas Germain, Elise Buret, Le Hoang Thanh Nguyen, Marion Cocheteux, Nicolas Touya, Mélanie Dhayer, Romain Dubois, Frank Lafont, Sebastien Janel, Patrice Maboudou, Steve Lancel, Philippe Marchetti   +11 more
wiley   +1 more source

University Hospitals General Staff Meeting, January 26, 1933

, 1933
University of Minnesota. University of Minnesota Hospitals. (1933). University Hospitals General Staff Meeting, January 26, 1933.
University of Minnesota. University of Minnesota Hospitals
core  

BCG vaccination potentiates oxidative phosphorylation in neonatal myeloid‐derived suppressor cells

FEBS Open Bio, EarlyView.
BCG vaccination enhances oxidative phosphorylation in neonatal MDSCs, impairing their immunosuppressive function. It upregulates electron transport chain genes and mitochondrial activity, increasing ATP and oxygen consumption. Pharmacological OXPHOS inhibition partially restores suppressive capacity, confirming causality.
Yingying Chen, Hui Li
wiley   +1 more source

University Hospitals General Staff Meeting, February 25, 1932

, 1932
University of Minnesota. University of Minnesota Hospitals. (1932). University Hospitals General Staff Meeting, February 25, 1932.
University of Minnesota. University of Minnesota Hospitals
core  

University Hospitals Staff Meeting Bulletin, November 8, 1934

, 1934
University of Minnesota. University of Minnesota Hospitals. (1934). University Hospitals Staff Meeting Bulletin, November 8, 1934.
University of Minnesota. University of Minnesota Hospitals
core  

Emergency and disaster preparedness in the zonal hospitals in the Somali Regional State, Ethiopia: a cross-sectional study. [PDF]

Res Health Serv Reg
Farah B, Pavlova M, Groot W.
europepmc   +1 more source

Aging Is a Key Driver for Adult Acute Myeloid Leukemia

Aging and Cancer, EarlyView.
Acute myeloid leukemia (AML) is a classical age‐related hematologic malignancy, and a key driver of AML is aging, which profoundly regulates intrinsic factors such as genomic instability, epigenetic reprogramming, and metabolic dysregulation, and alters bone marrow microenvironment.
Rong Yin, Haojian Zhang
wiley   +1 more source