This study presents a novel AI‐based diagnostic approach—comprehensive serum glycopeptide spectra analysis (CSGSA)—that integrates tumor markers and enriched glycopeptides from serum. Using a neural network model, this method accurately distinguishes liver and pancreatic cancers from healthy individuals.
Motoyuki Kohjima+6 more
wiley +1 more source
A Risk-Adjusted Model for Ovarian Cancer Care and Disparities in Access to High-Performing Hospitals. [PDF]
ObjectiveTo validate the observed/expected ratio for adherence to ovarian cancer treatment guidelines as a risk-adjusted measure of hospital quality care, and to identify patient characteristics associated with disparities in access to high-performing ...
Bristow, Robert E+4 more
core
HOSPITAL FOR DISEASES OF WOMEN AND CHILDREN, CORK. [PDF]
H. Macnaughton Jones
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Exploring the role of cyclin D1 in the pathogenesis of multiple myeloma beyond cell cycle regulation
Cyclin D1 overexpression altered the cell adhesion pathway, while cyclin D2 upregulation had less impact on pathway enrichment analysis. Multiple myeloma (MM) patients with cyclin D1 overexpression showed reduced CD56 expression and increased circulating tumor cells (CTC) levels, suggesting that cyclin D1 may contribute to MM cell dissemination ...
Ignacio J. Cardona‐Benavides+13 more
wiley +1 more source
Economic studies showing positive competition effects on hospital performance fully controlled for the factors cited by recent critics [PDF]
Criticisms have been made of recent influential studies that show improving performance in hospitals operating in more competitive environments compared with hospitals that have a local monopoly on care.
Cooper, Zack+3 more
core
A Lecture ON THE EVIDENCES OF AURICULAR FIBRILLATION, TREATED HISTORICALLY: Delivered at University College Hospital [PDF]
Trent R. Lewis
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Small extracellular vesicles are a promising source of diagnostic molecules. We conducted a comprehensive study, including transcriptome profiling and RT‐qPCR validation on large cohorts of samples. Diagnostic panels enabling sensitive detection of colorectal cancer and precancerous lesions were established. Some molecules were differentially expressed
Petra Vychytilova‐Faltejskova+26 more
wiley +1 more source
The American Hospital of the Twentieth Century. A Treatise on the Development of Medical Institutions, Both in Europe and in America, Since the Beginning of the Present Century. [PDF]
Edward Fletcher Stevens
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β‐TrCP overexpression enhances cisplatin sensitivity by depleting BRCA1
Low levels of β‐TrCP (Panel A) allow the accumulation of BRCA1 and CtIP, which facilitate the repair of cisplatin‐induced DNA damage via homologous recombination (HR) and promote tumor cell survival. In contrast, high β‐TrCP expression (Panel B) leads to BRCA1 and CtIP degradation, impairing HR repair, resulting in persistent DNA damage and apoptosis ...
Rocío Jiménez‐Guerrero+8 more
wiley +1 more source
Catholic Hospital Ethics [PDF]
This is the final Report of the Commission on Ethical and Religious Directives for Catholic Hospitals - a study commission established by the Catholic Theological Society of America in June, 1971.
Commission on Ethical and Religious Directives for Catholic Hospitals
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