Results 1 to 10 of about 432,533 (348)
Hypothiocyanite and host–microbe interactions
Molecular Microbiology, 2023 AbstractThe pseudohypohalous acid hypothiocyanite/hypothiocyanous acid (OSCN−/HOSCN) has been known to play an antimicrobial role in mammalian immunity for decades. It is a potent oxidant that kills bacteria but is non‐toxic to human cells. Produced from thiocyanate (SCN−) and hydrogen peroxide (H2O2) in a variety of body sites by peroxidase enzymes ...
Julia D. Meredith, Michael J. Gray
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Understanding the host-microbe interactions using metabolic modeling
Microbiome, 2021 The human gut harbors an enormous number of symbiotic microbes, which is vital for human health. However, interactions within the complex microbiota community and between the microbiota and its host are challenging to elucidate, limiting development in ...
Jack Jansma, Sahar El Aidy
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Chaotic signatures in host-microbe interactions
, 2022 AbstractHost-microbe interactions constitute dynamical systems that can be represented by mathematical formulations that determine their dynamic nature, and are categorized as deterministic, stochastic, or chaotic. Knowing the type of dynamical interaction is essential for understanding the system under study.
Sella Y +6 more
europepmc +3 more sources
Animal host–microbe interactions [PDF]
Journal of Animal Ecology, 2018 The ecology of infectious diseases, as we currently recognise it, has been a major field of scientific research for over a century. Since the early work of John Snow, describing the epidemiology of cholera in 1850s London, and Ronald Ross, describing the transmission dynamics of malaria at the end of the 19th century, through the mathematical models of
Bethany J. Hoye, Andy Fenton
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eLife, 2022 Mosquitoes transmit numerous pathogens, but large gaps remain in our understanding of their physiology. To facilitate explorations of mosquito biology, we have created Aegypti-Atlas (http://aegyptiatlas.buchonlab.com/), an online resource hosting RNAseq ...
Bretta Hixson +5 more
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Utility of nasal swabs for assessing mucosal immune responses towards SARS-CoV-2
Scientific Reports, 2023 SARS-CoV-2 has caused millions of infections worldwide since its emergence in 2019. Understanding how infection and vaccination induce mucosal immune responses and how they fluctuate over time is important, especially since they are key in preventing ...
Ericka Kirkpatrick Roubidoux +11 more
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Communications Biology, 2022 The kinase Itk is normally required for differentiation of IL-17-producing CD4 T-helper (Th)17 cells however, Elmore, Carter et al. now report that Itk can be bypassed during Th17 differentiation in Saccharopolyspora rectivirgula induced hypersensitivity
Jessica Elmore +9 more
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Nutrient cross-feeding in the microbial world. [PDF]
, 2014 The stability and function of a microbial community depends on nutritional interactions among community members such as the cross-feeding of essential small molecules synthesized by a subset of the population.
Seth, Erica C, Taga, Michiko E
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mSystems, 2023 The gut microbiota plays a crucial role in maintaining overall health and probiotics have emerged as a promising microbiota-targeted therapy for improving human health.
Jack Jansma +4 more
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Gnotobiotic Rodents: An In Vivo Model for the Study of Microbe–Microbe Interactions [PDF]
, 2016 Germ-free rodents have no microorganisms living in or on them, allowing researchers to specifically control an animal’s microbiota through the direct inoculation of bacteria of interest.
Luis G. Bermúdez-Humarán +2 more
core +3 more sources