Results 51 to 60 of about 451,880 (388)

Immunization with CSP and a RIG-I Agonist is Effective in Inducing a Functional and Protective Humoral Response Against Plasmodium

open access: yesFrontiers in Immunology, 2022
Malaria is a major public health concern, as a highly effective human vaccine remains elusive. The efficacy of a subunit vaccine targeting the most abundant protein of the sporozoite surface, the circumsporozoite protein (CSP) has been hindered by ...
Ana Rafaela Teixeira   +26 more
doaj   +1 more source

Host–parasite interactions and the evolution of ploidy [PDF]

open access: yesProceedings of the National Academy of Sciences, 2004
Although the majority of animals and plants, including humans, are dominated by the diploid phase of their life cycle, extensive diversity in ploidy level exists among eukaryotes, with some groups being primarily haploid whereas others alternate between haploid and diploid phases.
Scott L. Nuismer, Sarah P. Otto
openaire   +3 more sources

A game-theoretic model of interspecific brood parasitism with sequential decisions [PDF]

open access: yes, 2008
The interaction between hosts and parasites in bird populations has been studied extensively. This paper uses game-theoretic methods to model this interaction.
Banks   +40 more
core   +3 more sources

A brain cyst load-associated antigen is a Toxoplasma gondii biomarker for serodetection of persistent parasites and chronic infection

open access: yesBMC Biology, 2021
Background Biomarker discovery remains a major challenge for predictive medicine, in particular, in the context of chronic diseases. This is true for the widespread protozoan Toxoplasma gondii which establishes long-lasting parasitism in metazoans ...
Céline Dard   +9 more
doaj   +1 more source

The Rickettsial Ankyrin Repeat Protein 2 Is a Type IV Secreted Effector That Associates with the Endoplasmic Reticulum

open access: yesmBio, 2018
Strains of Rickettsia rickettsii, the tick-borne agent of Rocky Mountain spotted fever, vary considerably in virulence. Genomic comparisons of R. rickettsii strains have identified a relatively small number of genes divergent in an avirulent strain ...
Stephanie S. Lehman   +10 more
doaj   +1 more source

Neurophysiological Changes Induced by Chronic Toxoplasma gondii Infection [PDF]

open access: yes, 2017
Although the parasite Toxoplasma gondii is one of the most pervasive neurotropic pathogens in the world, the host-parasite interactions during CNS infection and the consequences of neurological infection are just beginning to be unraveled.
Cerávolo   +10 more
core   +2 more sources

Expanding the antimalarial toolkit: Targeting host–parasite interactions

open access: yesJournal of Experimental Medicine, 2016
Recent successes in malaria control are threatened by drug-resistant Plasmodium parasites and insecticide-resistant Anopheles mosquitoes, and first generation vaccines offer only partial protection.
J. Langhorne, P. Duffy
semanticscholar   +1 more source

Profiling the macrofilaricidal effects of flubendazole on adult female Brugia malayi using RNAseq

open access: yesInternational Journal for Parasitology: Drugs and Drug Resistance, 2016
The use of microfilaricidal drugs for the control of onchocerciasis and lymphatic filariasis (LF) necessitates prolonged yearly dosing. Prospects for elimination or eradication of these diseases would be enhanced by the availability of a macrofilaricidal
Maeghan O'Neill   +8 more
doaj   +1 more source

The potential for arms race and Red Queen coevolution in a protist host-parasite system [PDF]

open access: yes, 2014
11 pages, 6 figures, supporting information http://onlinelibrary.wiley.com/doi/10.1002/ece3.1314/suppinfoEcology and Evolution published by John Wiley & Sons Ltd.
Agrawal A.   +5 more
core   +4 more sources

Butyrate reduces adherent-invasive E. coli-evoked disruption of epithelial mitochondrial morphology and barrier function: involvement of free fatty acid receptor 3

open access: yesGut Microbes, 2023
Gut bacteria provide benefits to the host and have been implicated in inflammatory bowel disease (IBD), where adherent-invasive E. coli (AIEC) pathobionts (e.g., strain LF82) are associated with Crohn’s disease. E.
Samira A. Hamed   +11 more
doaj   +1 more source

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