Results 51 to 60 of about 451,880 (388)
Malaria is a major public health concern, as a highly effective human vaccine remains elusive. The efficacy of a subunit vaccine targeting the most abundant protein of the sporozoite surface, the circumsporozoite protein (CSP) has been hindered by ...
Ana Rafaela Teixeira+26 more
doaj +1 more source
Host–parasite interactions and the evolution of ploidy [PDF]
Although the majority of animals and plants, including humans, are dominated by the diploid phase of their life cycle, extensive diversity in ploidy level exists among eukaryotes, with some groups being primarily haploid whereas others alternate between haploid and diploid phases.
Scott L. Nuismer, Sarah P. Otto
openaire +3 more sources
A game-theoretic model of interspecific brood parasitism with sequential decisions [PDF]
The interaction between hosts and parasites in bird populations has been studied extensively. This paper uses game-theoretic methods to model this interaction.
Banks+40 more
core +3 more sources
Background Biomarker discovery remains a major challenge for predictive medicine, in particular, in the context of chronic diseases. This is true for the widespread protozoan Toxoplasma gondii which establishes long-lasting parasitism in metazoans ...
Céline Dard+9 more
doaj +1 more source
Strains of Rickettsia rickettsii, the tick-borne agent of Rocky Mountain spotted fever, vary considerably in virulence. Genomic comparisons of R. rickettsii strains have identified a relatively small number of genes divergent in an avirulent strain ...
Stephanie S. Lehman+10 more
doaj +1 more source
Neurophysiological Changes Induced by Chronic Toxoplasma gondii Infection [PDF]
Although the parasite Toxoplasma gondii is one of the most pervasive neurotropic pathogens in the world, the host-parasite interactions during CNS infection and the consequences of neurological infection are just beginning to be unraveled.
Cerávolo+10 more
core +2 more sources
Expanding the antimalarial toolkit: Targeting host–parasite interactions
Recent successes in malaria control are threatened by drug-resistant Plasmodium parasites and insecticide-resistant Anopheles mosquitoes, and first generation vaccines offer only partial protection.
J. Langhorne, P. Duffy
semanticscholar +1 more source
Profiling the macrofilaricidal effects of flubendazole on adult female Brugia malayi using RNAseq
The use of microfilaricidal drugs for the control of onchocerciasis and lymphatic filariasis (LF) necessitates prolonged yearly dosing. Prospects for elimination or eradication of these diseases would be enhanced by the availability of a macrofilaricidal
Maeghan O'Neill+8 more
doaj +1 more source
The potential for arms race and Red Queen coevolution in a protist host-parasite system [PDF]
11 pages, 6 figures, supporting information http://onlinelibrary.wiley.com/doi/10.1002/ece3.1314/suppinfoEcology and Evolution published by John Wiley & Sons Ltd.
Agrawal A.+5 more
core +4 more sources
Gut bacteria provide benefits to the host and have been implicated in inflammatory bowel disease (IBD), where adherent-invasive E. coli (AIEC) pathobionts (e.g., strain LF82) are associated with Crohn’s disease. E.
Samira A. Hamed+11 more
doaj +1 more source