Hologenomics: Systems-Level Host Biology [PDF]
mSystems, 2018 The hologenome concept of evolution is a hypothesis explaining host evolution in the context of the host microbiomes. As a hypothesis, it needs to be evaluated, especially with respect to the extent of fidelity of transgenerational coassociation of host ...
Kevin R. Theis
doaj +7 more sources
The Cell Biology of the Trichosporon-Host Interaction [PDF]
Frontiers in Cellular and Infection Microbiology, 2017 Fungi of the genus Trichosporon are increasingly recognized as causative agents of superficial and invasive fungal disease in humans. Although most species are considered commensals of the human skin and gastrointestinal tract, these basidiomycetes are ...
Cláudio Duarte-Oliveira +5 more
semanticscholar +8 more sources
Systems biology of host–microbe metabolomics [PDF]
WIREs Systems Biology and Medicine, 2015 The human gut microbiota performs essential functions for host and well‐being, but has also been linked to a variety of disease states, e.g., obesity and type 2 diabetes.
Almut Heinken, Ines Thiele
semanticscholar +5 more sources
Activity-based Tools for Interrogating Host Biology During Infection. [PDF]
Isr J Chem, 2023 Host cells sense and respond to pathogens by dynamically regulating cell signaling. The rapid modulation of signaling pathways is achieved by post-translational modifications (PTMs) that can alter protein structure, function, and/or binding interactions.
Ramanathan R, Hatzios SK.
europepmc +2 more sources
Host Biology and Anthropogenic Factors Affect Hepadnavirus Infection in a Neotropical Bat. [PDF]
Ecohealth, 2019 The tent-making bat hepatitis B virus (TBHBV) is a hepadnavirus closely related to human hepatitis B virus. The ecology of TBHBV is unclear. We show that it is widespread and highly diversified in Peters’ tent-making bats (Uroderma bilobatum) within ...
Hiller T +10 more
europepmc +2 more sources
Host Biology in Light of the Microbiome: Ten Principles of Holobionts and Hologenomes. [PDF]
PLoS Biol, 2015 Groundbreaking research on the universality and diversity of microorganisms is now challenging the life sciences to upgrade fundamental theories that once seemed untouchable.
Bordenstein SR, Theis KR.
europepmc +2 more sources
Modulation of Host Biology by Pseudomonas aeruginosa Quorum Sensing Signal Molecules: Messengers or Traitors. [PDF]
Front Microbiol, 2015 Bacterial cells sense their population density and respond accordingly by producing various signal molecules to the surrounding environments thereby trigger a plethora of gene expression. This regulatory pathway is termed quorum sensing (QS).
Liu YC, Chan KG, Chang CY.
europepmc +2 more sources
Hitchhiking of host biology by beneficial symbionts enhances transmission. [PDF]
Sci Rep, 2014 Transmission plays a key role in the evolution of symbiosis. Mixed mode transmission combines horizontal and vertical mechanisms for symbiont acquisition. However, features that enable mixed transmission are poorly understood.
Ott BM, Cruciger M, Dacks AM, Rio RV.
europepmc +2 more sources
Beyond phylotyping: understanding the impact of gut microbiota on host biology. [PDF]
Neurogastroenterol Motil, 2013 Reigstad CS, Kashyap PC.
europepmc +2 more sources
Host-microbiome interactions and recent progress into understanding the biology of acne vulgaris
Microbiome, 2018 Acne is one of the most common skin diseases worldwide and results in major health care costs and significant morbidity to severely affected individuals. However, the pathophysiology of this disorder is not well understood.
Alan M. O’Neill, Richard L. Gallo
openalex +2 more sources