Host Biology in Light of the Microbiome: Ten Principles of Holobionts and Hologenomes [PDF]
PLoS Biol, 2015 Groundbreaking research on the universality and diversity of microorganisms is now challenging the life sciences to upgrade fundamental theories that once seemed untouchable.
Seth R. Bordenstein, Kevin R. Theis
europepmc +4 more sources
Hologenomics: Systems-Level Host Biology [PDF]
mSystems, 2018 The hologenome concept of evolution is a hypothesis explaining host evolution in the context of the host microbiomes. As a hypothesis, it needs to be evaluated, especially with respect to the extent of fidelity of transgenerational coassociation of host ...
Kevin R. Theis
doaj +3 more sources
Activity-based Tools for Interrogating Host Biology During Infection. [PDF]
Isr J Chem, 2023 Host cells sense and respond to pathogens by dynamically regulating cell signaling. The rapid modulation of signaling pathways is achieved by post-translational modifications (PTMs) that can alter protein structure, function, and/or binding interactions.
Ramanathan R, Hatzios SK.
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Host biology, ecology and the environment influence microbial biomass and diversity in 101 marine fish species. [PDF]
Nat Commun, 2022 Fish are the most diverse and widely distributed vertebrates, yet little is known about the microbial ecology of fishes nor the biological and environmental factors that influence fish microbiota.
Minich JJ +12 more
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Host Biology and Anthropogenic Factors Affect Hepadnavirus Infection in a Neotropical Bat. [PDF]
Ecohealth, 2019 The tent-making bat hepatitis B virus (TBHBV) is a hepadnavirus closely related to human hepatitis B virus. The ecology of TBHBV is unclear. We show that it is widespread and highly diversified in Peters’ tent-making bats (Uroderma bilobatum) within ...
Hiller T +10 more
europepmc +2 more sources
Modulation of Host Biology by Pseudomonas aeruginosa Quorum Sensing Signal Molecules: Messengers or Traitors. [PDF]
Front Microbiol, 2015 Bacterial cells sense their population density and respond accordingly by producing various signal molecules to the surrounding environments thereby trigger a plethora of gene expression. This regulatory pathway is termed quorum sensing (QS).
Liu YC, Chan KG, Chang CY.
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Hitchhiking of host biology by beneficial symbionts enhances transmission. [PDF]
Sci Rep, 2014 Transmission plays a key role in the evolution of symbiosis. Mixed mode transmission combines horizontal and vertical mechanisms for symbiont acquisition. However, features that enable mixed transmission are poorly understood.
Ott BM, Cruciger M, Dacks AM, Rio RV.
europepmc +2 more sources
Host-Microbiome Interactions in the Era of Single-Cell Biology [PDF]
Frontiers in Cellular and Infection Microbiology, 2020 Microbes are the most prevalent form of life yet also the least well-understood in terms of their diversity. Due to a greater appreciation of their role in modulating host physiology, microbes have come to the forefront of biological investigation of ...
Prateek V. Sharma, Christoph A. Thaiss
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Host biology and genomic properties of Plumeria mosaic virus, a tobamovirus discovered in a temple tree in India co-infecting with frangipani mosaic virus [PDF]
Front Microbiol, 2022 Alok Kumar +3 more
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The cell biology of the Trichosporon-Host interaction [PDF]
Frontiers in Cellular and Infection Microbiology, 2017 Fungi of the genus Trichosporon are increasingly recognized as causative agents of superficial and invasive fungal disease in humans. Although most species are considered commensals of the human skin and gastrointestinal tract, these basidiomycetes are ...
Akoumianaki +81 more
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