\u3ci\u3eEpinotia Nisella\u3c/i\u3e: an Unrecorded Host and Mode of Feeding (Lepidoptera: Tortricidae) [PDF]
, 2017 The larva of Epinotia nisella is best known as a feeder in female catkins of Populus, primarily P. tremuloides Michx. in North America. In Minnesota, adults were reared from larvae boring in current-growth branchlets of P. balsamifera L., with no sign of
Miller, William E
core +2 more sources
Molecular Oncology, EarlyView.Generation of two normal and tumour (cancerous) paired human cell lines using an established tissue culture technique and their characterisation is described. Cell lines were characterised at cellular, protein, chromosome and gene expression levels and for HPV status.
Simon Broad +12 more
wiley +1 more source
Exploring the virulence gene interactome with CRISPR/dCas9 in the human malaria parasite
Molecular Systems Biology, 2020 Mutually exclusive expression of the var multigene family is key to immune evasion and pathogenesis in Plasmodium falciparum, but few factors have been shown to play a direct role.
Jessica M Bryant +8 more
doaj +1 more source
Current Status of Defensins and Their Role in Innate and Adaptive Immunity [PDF]
, 2002 Naturally occurring antimicrobial cationic polypeptides play a major role in innate and adaptive immunity. These polypeptides are found to be either linear and unstructured or structured through disulfide bonds.
Dentino, Andrew R., Raj, Periathamby A.
core +1 more source
The evolution, distribution and diversity of endogenous circoviral elements in vertebrate genomes [PDF]
, 2018 Circoviruses (family Circoviridae) are small, non-enveloped viruses that have short, single-stranded DNA genomes. Circovirus sequences are frequently recovered in metagenomic investigations, indicating that these viruses are widespread, yet they remain ...
Dennis, Tristan P.W. +5 more
core +1 more source
Candidalysin biology and activation of host cells
mBioABSTRACT Candida albicans is an opportunistic fungal pathogen that can cause life-threatening systemic infections and distressing mucosal infections. A major breakthrough in understanding C.
Léa Lortal +8 more
openaire +3 more sources
Strength through diversity: how cancers thrive when clones cooperate
Molecular Oncology, EarlyView.Intratumor heterogeneity can offer direct benefits to the tumor through cooperation between different clones. In this review, Kuiken et al. discuss existing evidence for clonal cooperativity to identify overarching principles, and highlight how novel technological developments could address remaining open questions.
Marije C. Kuiken +3 more
wiley +1 more source
Subtle, persistent shaping of the gut microbiome by host genes: A critical determinant of host biology. [PDF]
Cell Host Microbe, 2023 Dzierozynski L, Queen J, Sears CL.
europepmc +1 more source
Microbial Hub Taxa Link Host and Abiotic Factors to Plant Microbiome Variation
PLoS Biology, 2016 Plant-associated microorganisms have been shown to critically affect host physiology and performance, suggesting that evolution and ecology of plants and animals can only be understood in a holobiont (host and its associated organisms) context.
Matthew T. Agler +6 more
semanticscholar +1 more source
ATF4‐mediated stress response as a therapeutic vulnerability in chordoma
Molecular Oncology, EarlyView.We screened 5 chordoma cell lines against 100+ inhibitors of epigenetic and metabolic pathways and kinases and identified halofuginone, a tRNA synthetase inhibitor. Mechanistically halofuginone induces an integrated stress response, with eIF2alpha phosphorylation, activation of ATF4 and its target genes CHOP, ASNS, INHBE leading to cell death ...
Lucia Cottone +11 more
wiley +1 more source