Results 101 to 110 of about 1,352,426 (310)
Molecular cancer prevention: Intercepting disease
Molecular Oncology, EarlyView.Oncological practice must evolve, from treating established tumours to proactive cancer interception before clinical manifestation. This will require mechanistic insight into tumour initiation, validated biomarkers of early disease development and redesigned clinical trials, enabling cancer interception to become a core pillar of oncology with the ...
Charlotte Grieco +2 more
wiley +1 more source
Exploring the virulence gene interactome with CRISPR/dCas9 in the human malaria parasite
Molecular Systems Biology, 2020 Mutually exclusive expression of the var multigene family is key to immune evasion and pathogenesis in Plasmodium falciparum, but few factors have been shown to play a direct role.
Jessica M Bryant +8 more
doaj +1 more source
Trypanorhynch Assemblages Indicate Ecological and Phylogenetical Attributes of Their Elasmobranch Final Hosts [PDF]
, 2017 This study explores non-metric multidimensional scaling (nMDS) as a tool for investigating parasites as indicators of the elasmobranch biology. An attractive feature of nMDS is its ability to allow assemblage-level parasite data to be simultaneously ...
Palm, Harry W. +2 more
core +1 more source
Candidalysin biology and activation of host cells
mBioABSTRACT Candida albicans is an opportunistic fungal pathogen that can cause life-threatening systemic infections and distressing mucosal infections. A major breakthrough in understanding C.
Léa Lortal +8 more
openaire +3 more sources
Molecular Oncology, EarlyView.Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary +1 more
wiley +1 more source
Drosophila as a model system to study nonautonomous mechanisms affecting tumour growth and cell death [PDF]
, 2018 The study of cancer has represented a central focus in medical research for over a century. The great complexity and constant evolution of the pathology require the use of multiple research model systems and interdisciplinary approaches.
Cordero, Julia B. +2 more
core +3 more sources
Subtle, persistent shaping of the gut microbiome by host genes: A critical determinant of host biology. [PDF]
Cell Host Microbe, 2023 Dzierozynski L, Queen J, Sears CL.
europepmc +1 more source
Molecular Oncology, EarlyView.Both cg12821679MAPRE3 methylation and MAPRE3 expression are significantly associated with overall survival (OS) of non‐small cell lung cancer. Meanwhile, MAPRE3 expression significantly modified the effect of smoking cessation on OS. Smoking cessation benefits OS merely for patients with high MAPRE3 expression.
Chao Chen +14 more
wiley +1 more source
Anopheline salivary protein genes and gene families: an evolutionary overview after the whole genome sequence of sixteen Anopheles species [PDF]
, 2017 Background: Mosquito saliva is a complex cocktail whose pharmacological properties play an essential role in blood feeding by counteracting host physiological response to tissue injury.
ARCA', Bruno +3 more
core +2 more sources
Activity-based Tools for Interrogating Host Biology During Infection. [PDF]
Isr J Chem, 2023 Ramanathan R, Hatzios SK.
europepmc +1 more source