Results 11 to 20 of about 3,640,353 (386)

The role of the host-Neutrophil biology.

open access: yesPeriodontology 2000, 2023
Neutrophilic polymorphonuclear leukocytes (neutrophils) are myeloid cells packed with lysosomal granules (hence also called granulocytes) that contain a formidable antimicrobial arsenal.
I. Chapple   +4 more
semanticscholar   +3 more sources

Organoids as host models for infection biology – a review of methods [PDF]

open access: yesExperimental & Molecular Medicine, 2021
Infectious diseases are a major threat worldwide. With the alarming rise of antimicrobial resistance and emergence of new potential pathogens, a better understanding of the infection process is urgently needed.
Carmen Aguilar   +5 more
semanticscholar   +5 more sources

Inorganic Polyphosphate in Host and Microbe Biology.

open access: yesTrends in Microbiology, 2021
Inorganic polyphosphate (polyP) is produced by both bacteria and their eukaryotic hosts, and it appears to play multiple important roles in the interactions between those organisms. However, the detailed mechanisms of how polyP synthesis is regulated in bacteria, and how it influences both bacterial and host biology, remain largely unexplored.
Marvin Q. Bowlin, M. Gray
semanticscholar   +3 more sources

Host-aware synthetic biology [PDF]

open access: yesCurrent Opinion in Systems Biology, 2019
Abstract Unnatural gene expression imposes a load on engineered microorganisms which decreases their growth and subsequent production yields, a phenomenon known as burden. In the last decade, the field of synthetic biology has made progress on the development of biomolecular feedback control systems and other approaches that can improve the growth of
Alice Boo, T. Ellis, G. Stan
semanticscholar   +4 more sources

Systems biology and the host response to viral infection [PDF]

open access: bronzeNature Biotechnology, 2007
Will our increasing understanding of virus-host interactions translate into a new generation of antiviral therapeutics or steer us toward an expensive journey to nowhere?
Seng-Lai Tan   +4 more
openalex   +4 more sources

Advanced Multiplex Loop Mediated Isothermal Amplification (mLAMP) Combined with Lateral Flow Detection (LFD) for Rapid Detection of Two Prevalent Malaria Species in India and Melting Curve Analysis

open access: yesDiagnostics, 2021
Isothermal techniques with lateral flow detection have emerged as a point of care (POC) technique for malaria, a major parasitic disease in tropical countries such as India.
Supriya Sharma   +8 more
doaj   +1 more source

Nationwide spatiotemporal drug resistance genetic profiling from over three decades in Indian Plasmodium falciparum and Plasmodium vivax isolates

open access: yesMalaria Journal, 2023
Background Drug resistance is a serious impediment to efficient control and elimination of malaria in endemic areas. Methods This study aimed at analysing the genetic profile of molecular drug resistance in Plasmodium falciparum and Plasmodium vivax ...
Loick P. Kojom Foko   +5 more
doaj   +1 more source

The spectrum of clinical biomarkers in severe malaria and new avenues for exploration

open access: yesVirulence, 2022
Globally, malaria is a public health concern, with severe malaria (SM) contributing a major share of the disease burden in malaria endemic countries. In this context, identification and validation of SM biomarkers are essential in clinical practice. Some
Loick Pradel Kojom Foko   +6 more
doaj   +1 more source

Pathophysiology of Cerebral Malaria: Implications of MSCs as A Regenerative Medicinal Tool

open access: yesBioengineering, 2022
The severe form of malaria, i.e., cerebral malaria caused by Plasmodium falciparum, is a complex neurological syndrome. Surviving persons have a risk of behavioral difficulties, cognitive disorders, and epilepsy.
Amrendra Chaudhary   +3 more
doaj   +1 more source

CD4+ICOS+Foxp3+: a sub-population of regulatory T cells contribute to malaria pathogenesis

open access: yesMalaria Journal, 2022
Background Regulatory T cells are known to play a key role to counter balance the protective immune response and immune mediated pathology. However, the role of naturally occurring regulatory cells CD4+CD25+Foxp3 + in malaria infection during the disease
Rubika Chauhan   +5 more
doaj   +1 more source

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