Results 101 to 110 of about 5,613,148 (257)

Single‐cell DNA methylation profiling: Technologies, computation, and applications in precision oncology

open access: yesMolecular Oncology, EarlyView.
Single‐cell DNA methylation (scDNAme) profiling maps epimutational clonal evolution, revealing mechanisms of malignancy and therapeutic resistance across diverse cancer types. By providing a high‐resolution landscape of intratumoral heterogeneity, these technologies empower precise patient stratification, guide the development of enhanced ...
Ik Soo Kim
wiley   +1 more source

Geminiviruses and Plant Hosts: A Closer Examination of the Molecular Arms Race

open access: yesViruses, 2017
Geminiviruses are plant-infecting viruses characterized by a single-stranded DNA (ssDNA) genome. Geminivirus-derived proteins are multifunctional and effective regulators in modulating the host cellular processes resulting in successful infection.
Shunmugiah V. Ramesh   +4 more
doaj   +1 more source

PANoptosis in the pathogenesis of myelodysplastic syndromes

open access: yesMolecular Oncology, EarlyView.
PANoptosis, a combination of three types of programmed cell death, is mediated by a large protein complex called a PANoptosome. In healthy bone marrow hematopoietic cells, PANoptosis is restricted by inhibitory signaling. In MDS, bone marrow cells become sensitive to the PANoptotic stimuli due to the aberrant inactivation of inhibitory signaling or ...
Rohit Thalla   +4 more
wiley   +1 more source

ADP‐ribosylation: An emerging regulator of the epigenome

open access: yesMolecular Oncology, EarlyView.
ADP‐ribosylation has emerged as a dynamic epigenetic signaling mechanism that modifies histones and chromatin‐associated proteins. Through coordinated PARylation and MARylation, it integrates with other histone modifications to regulate chromatin structure, transcription factor activity, and gene expression, influencing genome function and disease ...
Cristel V. Camacho   +2 more
wiley   +1 more source

Effects of plant tissue factors on the acceptance of four greenhouse vegetable host plants by the greenhouse whitefly: an Electrical Penetration Graph (EPG) study

open access: yesEuropean Journal of Entomology, 2001
A combination of biological control and host-plant resistance is needed to control greenhouse whitefly, Trialeurodes vaporariorum (Westwood). The high level of susceptibility of several host plants to whitefly, based on their performance on these plants,
Hong LEI, Joop C. VAN LENTEREN, Ru M. XU
doaj   +1 more source

Lipopolysaccharide uptake is augmented in lipopolysaccharide‐tolerant mouse macrophage‐like cells via increased CD14 expression

open access: yesFEBS Open Bio, EarlyView.
In normal (nontolerant) cells, CD14 is crucial for both LPS uptake and LPS signaling. In LPS‐tolerant cells, in which LPS‐induced TNF‐α and IFN‐β production is suppressed, there is a dramatic increase in surface CD14 expression. The overexpressed CD14 in LPS‐tolerant cells is responsible for the enhanced LPS uptake without inducing pro‐inflammatory ...
Saeka Nishihara   +3 more
wiley   +1 more source

Host specificity and genetics of host resistance in the "Daphnia-Pasteuria" host-parasite system [PDF]

open access: yes, 2012
Antagonistic coevolution plays an important role in a large number of evolutionary and ecological phenomena. Furthermore, according to the Red Queen Theory coevolution between hosts and their parasites may explain the maintenance of sexual reproduction ...
Luijckx, Pepijn
core   +1 more source

Soybean microbiome composition and the impact of host plant resistance. [PDF]

open access: yesFront Plant Sci, 2023
Tran DT   +4 more
europepmc   +1 more source

A Phytophthora sojae effector suppresses endoplasmic reticulum stress-mediated immunity by stabilizing plant Binding immunoglobulin Proteins

open access: yesNature Communications, 2016
Phytophthora pathogens manipulate host plant immune responses by secreting effector proteins into plant cells. Here, Jing et al. show that the Phytophthora sojaeAvh262 effector negatively regulates plant resistance by binding to host BiP proteins and ...
Maofeng Jing   +14 more
doaj   +1 more source

Keeping Control: The Role of Senescence and Development in Plant Pathogenesis and Defense

open access: yesPlants, 2015
Many plant pathogens show interactions with host development. Pathogens may modify plant development according to their nutritional demands. Conversely, plant development influences pathogen growth.
Eva Häffner   +2 more
doaj   +1 more source

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