Results 41 to 50 of about 988,906 (309)

Cooperative secretions facilitate host range expansion in bacteria [PDF]

, 2014
The majority of emergent human pathogens are zoonotic in origin, that is, they can transmit to humans from other animals. Understanding the factors underlying the evolution of pathogen host range is therefore of critical importance in protecting human ...
Viana, Mafalda, Brown, Sam P., Brown, Sam P, McNally, Luke   +3 more
core   +1 more source

The Role of Hematopoietic Cell Transplantation in Ataxia‐Telangiectasia

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Ataxia‐telangiectasia (A‐T) is a DNA repair disorder characterized by neurodegeneration, immunodeficiency, and cancer predisposition. Hematopoietic cell transplantation (HCT) is an established therapy in related disorders such as Fanconi anemia (FA) and Nijmegen breakage syndrome (NBS), but its role in A‐T is unclear.
Laila Alkhouli, Seth Rotz, Masatoshi Takagi, Richa Sharma   +3 more
wiley   +1 more source

Which morphological characteristics are most influenced by the host matrix in downy mildews? : A case study in Pseudoperonospora cubensis

, 2012
Before the advent of molecular phylogenetics, species concepts in the downy mildews, an economically important group of obligate biotrophic oomycete pathogens, have mostly been based upon host range and morphology.
Marco Thines, Runge, Fabian, Ndambi, Beninweck, Thines Marco, Fabian Runge, Beninweck Ndambi, Thines, Marco, Runge Fabian, Ndambi Beninweck   +8 more
core   +1 more source

Prognosis of Long‐Term Continuous Renal Replacement Therapy and the Impact of Combined Continuous Intravenous Sodium Infusion Therapy

Therapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Introduction Patients requiring long‐term continuous renal replacement therapy (CRRT) generally have poor prognoses. This study evaluated whether adding continuous intravenous sodium infusion (cIVNa) is associated with improved hemodynamics and outcomes in patients undergoing long‐term CRRT for ≥ 7 days.
Akinori Yamaguchi, Atsuyoshi Mita, Kosuke Sonoda, Makoto Harada, Koji Hashimoto, Hiroshi Imamura, Yuji Kamijo   +6 more
wiley   +1 more source

Poxviruses in Bats … so What?

Viruses, 2014
Poxviruses are important pathogens of man and numerous domestic and wild animal species. Cross species (including zoonotic) poxvirus infections can have drastic consequences for the recipient host.
Kate S. Baker, Pablo R. Murcia
doaj   +1 more source

The evolution of parasite host range in heterogeneous host populations

Journal of Evolutionary Biology, 2020
Abstract Theory on the evolution of niche width argues that resource heterogeneity selects for niche breadth. For parasites, this theory predicts that parasite populations will evolve, or maintain, broader host ranges when selected in genetically diverse host populations relative to homogeneous host populations ...
Amanda K. Gibson, Helena Baffoe‐Bonnie, McKenna J. Penley, Julie Lin, Raythe Owens, Arooj Khalid, Levi T. Morran   +6 more
openaire   +3 more sources

Enteropathogenic E. coli shows delayed attachment and host response in human jejunum organoid‐derived monolayers compared to HeLa cells

FEBS Letters, EarlyView.
Enteropathogenic E. coli (EPEC) infects the human intestinal epithelium, resulting in severe illness and diarrhoea. In this study, we compared the infection of cancer‐derived cell lines with human organoid‐derived models of the small intestine. We observed a delayed in attachment, inflammation and cell death on primary cells, indicating that host ...
Mastura Neyazi, Pilar Samperio Ventayol, Natalie Burkard, Nicolas Schlegel, Carmen Aguilar, Sina Bartfeld   +5 more
wiley   +1 more source

Reciprocal control of viral infection and phosphoinositide dynamics

FEBS Letters, EarlyView.
Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley   +1 more source

Host range and growth of Stem and Bulb Nematode (Ditylenchus dipsaci) populations isolated from garlic and chicory

Plant Protection Science, 2005
Host range and growth of two Ditylenchus dipsaci (Stem and Bulb Nematode) populations on onion, garlic, leek, spinach and chicory were compared. Inoculation was conducted by placing a droplet of 1.5% CMC suspension containing nematodes between the first ...
Ondřej Douda
doaj   +1 more source

M148R and M149R are two virulence factors for myxoma virus pathogenesis in the European rabbit [PDF]

, 2009
Myxoma virus (MYXV), a member of the Poxviridae family, is the agent responsible for myxomatosis, a fatal disease in the European rabbit (Oryctolagus cuniculus).
Camus-Bouclainville, Christelle, Sophie Blanié, Blanié, Sophie, Christelle Camus-Bouclainville, Mortier, Jérémy, Stéphane Bertagnoli, Mortier, J, Maxence Delverdier, Bertagnoli, Stéphane, Jérémy Mortier, Delverdier, Maxence   +10 more
core   +1 more source