Results 81 to 90 of about 1,599,750 (302)

Circular RNA expression landscapes in myelodysplastic neoplasms: Associations with mutational signatures and disease progression

open access: yesMolecular Oncology, EarlyView.
In this explorative study, the abundance of circular RNA molecules in bone marrow stem cells was found to be elevated in patients with high‐risk myelodysplastic neoplasms, and to be associated with an increased risk of progression to acute myeloid leukemia.
Eileen Wedge   +17 more
wiley   +1 more source

Suitability and Profitability of a Cereal Aphid for the Parasitoid Aphidius platensis in the Context of Conservation Biological Control of Myzus persicae in Orchards

open access: yesInsects, 2020
The use of cover crops can promote the abundance and early arrival of populations of natural enemies. Cereal cover crops between orchards rows could encourage the early arrival of the parasitoid Aphidius platensis, as they offer alternative winter hosts (
Jeniffer K. Alvarez-Baca   +4 more
doaj   +1 more source

A Central Excess of Stripped-Envelope Supernovae within Disturbed Galaxies

open access: yes, 2012
This paper presents an analysis of core-collapse supernova distributions in isolated and interacting host galaxies, paying close attention to the selection effects involved in conducting host galaxy supernova studies.
Alonso-Herrero   +105 more
core   +1 more source

International medical electives in selected African countries: A phenomenological study on host experience [PDF]

open access: yes, 2018
Objectives: To explore the host experience on international medical electives at a selection of hospitals in low- and middle-income countries in Africa.
Craig, Pippa   +2 more
core   +2 more sources

Host Plant Specialization Driven by Sexual Selection [PDF]

open access: yesThe American Naturalist, 2007
We propose a new mechanism based on sexual selection to explain the evolution of diet breadth in insects. More specifically, we show that mate choice in females for certain diet-derived male pheromones can be exploited by maternal effect genes that preferentially place offspring on a specific host plant, resulting in specialization.
Quental, Tiago   +2 more
openaire   +3 more sources

Dimethyl fumarate combined with cisplatin at subcytotoxic doses sensitizes cervical cancer toward ferroptosis and apoptosis through GSH restriction and p53 (re)activation

open access: yesMolecular Oncology, EarlyView.
Dimethyl fumarate (DMF) reduces growth of HPV‐positive cervical cancer spheroids and induces ferroptosis in cervical cancer cells via blocking SLC7A11/Glutathione (GSH) axis. Combination of subcytotoxic doses of DMF and cisplatin (CDDP) further suppresses spheroid growth and drives cell death in 2D culture models.
Carolina Punziano   +6 more
wiley   +1 more source

Graphosoma lineatum L. Heteroptera, Pentatomidae ’un farklı besinlerdeki biyolojik parametrelerinin belirlenmesi

open access: yesJournal of Agricultural Sciences, 2009
Süne Eurygaster spp. yumurta parazitoitleri için uygun konukçu olan Grapohosoma lineatum L. ’un fekonditesi, erginlerin yaşam süreleri, preovipozisyon, ovipozisyon, postovipozisyon süreleri ile nimflerinin toplam gelişme süresi, dönemlerine göre ...
Gö -   +7 more
doaj  

Population gene introgression and high genome plasticity for the zoonotic pathogen Streptococcus agalactiae [PDF]

open access: yes, 2019
The influence that bacterial adaptation (or niche partitioning) within species has on gene spillover and transmission among bacteria populations occupying different niches is not well understood.
Abbott   +124 more
core   +2 more sources

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

open access: yesMolecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric   +10 more
wiley   +1 more source

E2A selectively regulates TGF‐β–induced apoptosis in KRAS‐mutant non‐small cell lung cancer

open access: yesMolecular Oncology, EarlyView.
Ability to induce apoptosis by TGF‐β is frequently lost in advanced lung adenocarcinoma despite intact TGF‐β signaling. We identify E2A as a mutant KRAS–dependent mediator of resistance to TGF‐β–induced apoptosis. TGF‐β induces E2A via SMAD3 in mutant KRAS cells, and E2A silencing restores apoptosis and enhances radiation response in cell lines ...
Sergei Chuikov   +3 more
wiley   +1 more source

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