Results 91 to 100 of about 508,470 (286)
Shuttle/GPSPAC experimentation study [PDF]
The utilization is discussed of the GPSPAC, which is presently being developed to be used on the low altitude host vehicle (LAHV), for possible use in the shuttle avionics system to evaluate shuttle/GPS navigation performance.
Flack, J. F., Moses, J.
core +1 more source
Load Balancing and Virtual Machine Allocation in Cloud-based Data Centers [PDF]
, 2018 As cloud services see an exponential increase in consumers, the demand for faster processing of data and a reliable delivery of services becomes a pressing concern. This puts a lot of pressure on the cloud-based data centers, where the consumers’ data is
Ghodke, Saily Satish
core +1 more source
Service Chain (SC) Mapping with Multiple SC Instances in a Wide Area Network
, 2017 Network Function Virtualization (NFV) aims to simplify deployment of network services by running Virtual Network Functions (VNFs) on commercial off-the-shelf servers.
Gupta, Abhishek +3 more
core +1 more source
E2A selectively regulates TGF‐β–induced apoptosis in KRAS‐mutant non‐small cell lung cancer
Molecular Oncology, EarlyView.Ability to induce apoptosis by TGF‐β is frequently lost in advanced lung adenocarcinoma despite intact TGF‐β signaling. We identify E2A as a mutant KRAS–dependent mediator of resistance to TGF‐β–induced apoptosis. TGF‐β induces E2A via SMAD3 in mutant KRAS cells, and E2A silencing restores apoptosis and enhances radiation response in cell lines ...
Sergei Chuikov +3 more
wiley +1 more source
mBio, 2018 A core principle of bacterial pathogenesis is that pathogens preferentially utilize metabolites that commensal bacteria do not in order to sidestep nutritional competition.
Carol A. Rowley +2 more
doaj +1 more source
Molecular Oncology, EarlyView.We analyze cisplatin–DNA adducts (CDAs) and double‐strand breaks (DSBs) in a cell‐cycle‐dependent manner. We find that CDAs form similarly across all cell cycle phases. DSBs arise only in S‐phase. CDAs might not directly impair DSB repair, but S‐phase DSB lesions evolve in the presence of CDAs and disrupt repair in G2, also causing radiosensitization ...
Ye Qiu +10 more
wiley +1 more source
RCD: Rapid Close to Deadline Scheduling for Datacenter Networks
, 2017 Datacenter-based Cloud Computing services provide a flexible, scalable and yet economical infrastructure to host online services such as multimedia streaming, email and bulk storage. Many such services perform geo-replication to provide necessary quality
Madni, Asad M. +3 more
core +2 more sources
Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer
Molecular Oncology, EarlyView.Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley +1 more source
Host-utilization differences between larval and nymphal deer ticks in northeastern U.S. sites enzootic for Borrelia burgdorferi sensu stricto. [PDF]
Ticks Tick Borne Dis, 2023 Goethert HK +3 more
europepmc +1 more source
Molecular cancer prevention: Intercepting disease
Molecular Oncology, EarlyView.Oncological practice must evolve, from treating established tumours to proactive cancer interception before clinical manifestation. This will require mechanistic insight into tumour initiation, validated biomarkers of early disease development and redesigned clinical trials, enabling cancer interception to become a core pillar of oncology with the ...
Charlotte Grieco +2 more
wiley +1 more source