Results 81 to 90 of about 161,439 (263)

Cryptococcus neoformans Requires a Functional Glycolytic Pathway for Disease but Not Persistence in the Host

open access: yesmBio, 2011
Cryptococcus neoformans is an important fungal pathogen of immunocompromised individuals, with a close relative, Cryptococcus gattii, emerging as a serious threat for the immunocompetent. During initial infection, C. neoformans colonizes the airspaces of
Michael S. Price   +7 more
doaj   +1 more source

An epithelial GPR35 isoform supports tumor‐associated transcriptional and metabolic phenotypes

open access: yesFEBS Letters, EarlyView.
GPR35 generates two functionally distinct isoforms with previously unresolved roles. GPR35‐short mediates immune‐cell chemotaxis, while GPR35‐long is enriched in colorectal cancer epithelium, where it supports increased metabolism, proliferation, and tumor‐associated transcriptional programs.
Jørgen D. Rønneberg   +14 more
wiley   +1 more source

Parallelisms and Contrasts in the Diverse Ecologies of the Anaplasma phagocytophilum and Borrelia burgdorferi Complexes of Bacteria in the Far Western United States

open access: yesVeterinary Sciences, 2016
Anaplasma phagocytophilum and Borrelia burgdorferi are two tick-borne bacteria that cause disease in people and animals. For each of these bacteria, there is a complex of closely related genospecies and/or strains that are genetically distinct and have ...
Nicole Stephenson, Janet Foley
doaj   +1 more source

Peripheral lysosomes recruit PLEKHG3 to focal adhesions and restrain protrusion dynamics

open access: yesFEBS Letters, EarlyView.
Proximity‐dependent labeling at the LAMTOR complex revealed the Rho GEF PLEKHG3 as a lysosome‐proximal protein directing the study toward the influence of lysosome positioning on actin dynamics and cell motility. We show that PLEKHG3 colocalizes with lysosomes at focal adhesion sites and observe that forced peripheral dispersion of lysosomes hinders ...
Rainer Ettelt   +8 more
wiley   +1 more source

Revisiting Hyaluronan Catabolism in Bacteroides: Pathway Conservation, Overlooked Proteins, and Predictive Accuracy

open access: yesMicrobiologyOpen
The ability of gut microbes to degrade host‐ and diet‐derived glycans is central to microbiome ecology and host interactions, yet predicting these functions in silico remains challenging.
Martin Sindelar   +6 more
doaj   +1 more source

The microbiome in human skin aging

open access: yesFEBS Letters, EarlyView.
Age‐related skin changes encompass the well‐known visible phenotypic alterations, together with microbiome dysbiosis and a series of molecular aging hallmarks. These hallmarks characterize not only a fully stablished aged phenotype but also the skin aging process itself.
Manuel Huerta Arana   +3 more
wiley   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

open access: yesMolecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Metaproteomics reveals parallel utilization of colonic mucin glycans and dietary fibers by the human gut microbiota

open access: yesiScience
Summary: A diet lacking dietary fibers promotes the expansion of gut microbiota members that can degrade host glycans, such as those on mucins. The microbial foraging on mucin has been associated with disruptions of the gut-protective mucus layer and ...
Grete Raba   +8 more
doaj   +1 more source

Perspective d'utilisation des termitières dans l'amélioration de la fertilité des sols tropicaux : cas d'une expérimentation en pots de végétation [PDF]

open access: yesTropicultura, 1992
Perspective of termitary mounds utilization in improvement of tropical soil fertility : case of a pot vegetation experiment. The fertilizing power offive termitary mounds of Yakonde soil serie (Y2) in Yangambi has been tested by rice growing in ...
Endubu, M.   +3 more
doaj  

Development and utilization of common roughage in southern China

open access: yesSiliao yanjiu, 2021
Roughage is the main component of ruminant diet, which provides lots of nutrients for rumen microorganisms and host animals, mainly including forage, straw, and agricultural by-products.
Zhou CHI   +6 more
doaj  

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