Results 71 to 80 of about 172,901 (216)

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

open access: yesMolecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Circular RNA expression landscapes in myelodysplastic neoplasms: Associations with mutational signatures and disease progression

open access: yesMolecular Oncology, EarlyView.
In this explorative study, the abundance of circular RNA molecules in bone marrow stem cells was found to be elevated in patients with high‐risk myelodysplastic neoplasms, and to be associated with an increased risk of progression to acute myeloid leukemia.
Eileen Wedge   +17 more
wiley   +1 more source

Navigating the translational labyrinth of the gut microbiota

open access: yesScientific Reports
Modern gut microbiota research, enabled by high-throughput sequencing, has established gastrointestinal microbial communities as integral components of host biology across the animals and humans.
Ching Jian
doaj   +1 more source

Metaproteomics reveals parallel utilization of colonic mucin glycans and dietary fibers by the human gut microbiota

open access: yesiScience
Summary: A diet lacking dietary fibers promotes the expansion of gut microbiota members that can degrade host glycans, such as those on mucins. The microbial foraging on mucin has been associated with disruptions of the gut-protective mucus layer and ...
Grete Raba   +8 more
doaj   +1 more source

Perspective d'utilisation des termitières dans l'amélioration de la fertilité des sols tropicaux : cas d'une expérimentation en pots de végétation [PDF]

open access: yesTropicultura, 1992
Perspective of termitary mounds utilization in improvement of tropical soil fertility : case of a pot vegetation experiment. The fertilizing power offive termitary mounds of Yakonde soil serie (Y2) in Yangambi has been tested by rice growing in ...
Endubu, M.   +3 more
doaj  

Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer

open access: yesMolecular Oncology, EarlyView.
Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley   +1 more source

Development and utilization of common roughage in southern China

open access: yesSiliao yanjiu, 2021
Roughage is the main component of ruminant diet, which provides lots of nutrients for rumen microorganisms and host animals, mainly including forage, straw, and agricultural by-products.
Zhou CHI   +6 more
doaj  

Metastasis on pause: How dormant tumor cells stay hidden within the tumor microenvironment and evade immune surveillance

open access: yesMolecular Oncology, EarlyView.
Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary   +1 more
wiley   +1 more source

An updated list of parasitic cuckoos and their hosts in China

open access: yesAvian Research
Avian brood parasitism is a unique reproductive behavior in which parasitic birds depend on other species to incubate their eggs and raise their offspring. In China, there are 20 species of cuckoos in the family Cuculidae, order Cuculiformes, of which 17
Jianping Liu, Sidan Lin, Wei Liang
doaj   +1 more source

Loss of IGF‐1R impairs DNA‐PKcs recruitment to chromatin leading to defective end‐joining

open access: yesMolecular Oncology, EarlyView.
IGF‐1R promotes radioresistance by facilitating DNA‐PKcs recruitment to chromatin, enabling non‐homologous end‐joining (NHEJ) repair of double‐strand breaks. Inhibition or loss of IGF‐1R disrupts this recruitment to damage sites, driving compensatory reliance on microhomology‐mediated end‐joining (MMEJ) repair.
Matthew O. Ellis   +3 more
wiley   +1 more source

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