Results 61 to 70 of about 248,785 (301)
Collocation Games and Their Application to Distributed Resource Management [PDF]
, 2009 We introduce Collocation Games as the basis of a general framework for modeling, analyzing, and facilitating the interactions between the various stakeholders in distributed systems in general, and in cloud computing environments in particular.
Bestavros, Azer +2 more
core +1 more source
Molecular Oncology, EarlyView.Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon +13 more
wiley +1 more source
Energies, 2019 There has been an increasing trend of integrating photovoltaic power plants (PVs). One of the important challenges for distribution system operators is to evaluate the total installed power of a PV that a particular network can host (or PV hosting ...
Miha Grabner +4 more
doaj +1 more source
Multi-capacity bin packing with dependent items and its application to the packing of brokered workloads in virtualized environments [PDF]
, 2017 Providing resource allocation with performance predictability guarantees is increasingly important in cloud platforms, especially for data-intensive applications, in which performance depends greatly on the available rates of data transfer between ...
Bassem, Christine, Bestavros, Azer
core +1 more source
Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment
Molecular Oncology, EarlyView.This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley +1 more source
An extended hosting capacity approach including energy storage
, 2023 This chapter proposes an evolved concept of ”hosting capacity” using the term of ”feasible region” for installing additional loads or generations. Through converting the grid model into a more compact one, ”hosting capacity region” not only is promising to further exploit the grid potential for power delivery, but also benefits grid operation ...
Gong, Sicheng +3 more
openaire +1 more source
Molecular Oncology, EarlyView.We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric +10 more
wiley +1 more source
E2A selectively regulates TGF‐β–induced apoptosis in KRAS‐mutant non‐small cell lung cancer
Molecular Oncology, EarlyView.Ability to induce apoptosis by TGF‐β is frequently lost in advanced lung adenocarcinoma despite intact TGF‐β signaling. We identify E2A as a mutant KRAS–dependent mediator of resistance to TGF‐β–induced apoptosis. TGF‐β induces E2A via SMAD3 in mutant KRAS cells, and E2A silencing restores apoptosis and enhances radiation response in cell lines ...
Sergei Chuikov +3 more
wiley +1 more source
Impact of digital time delay on the stable grid‐hosting capacity of large‐scale centralised PV plant
IET Renewable Power Generation, 2021 Digital control system has been widely used for the inverters in PV plant. However, the effects of digital time delay of digital control system on grid‐connected PV plants have not been fully studied.
Jinhong Liu, Marta Molinas
doaj +1 more source
Molecular Oncology, EarlyView.We analyze cisplatin–DNA adducts (CDAs) and double‐strand breaks (DSBs) in a cell‐cycle‐dependent manner. We find that CDAs form similarly across all cell cycle phases. DSBs arise only in S‐phase. CDAs might not directly impair DSB repair, but S‐phase DSB lesions evolve in the presence of CDAs and disrupt repair in G2, also causing radiosensitization ...
Ye Qiu +10 more
wiley +1 more source