Results 81 to 90 of about 689,866 (345)

Predictors of response and rational combinations for the novel MCL‐1 inhibitor MIK665 in acute myeloid leukemia

open access: yesMolecular Oncology, EarlyView.
This study characterizes the responses of primary acute myeloid leukemia (AML) patient samples to the MCL‐1 inhibitor MIK665. The results revealed that monocytic differentiation is associated with MIK665 sensitivity. Conversely, elevated ABCB1 expression is a potential biomarker of resistance to the treatment, which can be overcome by the combination ...
Joseph Saad   +17 more
wiley   +1 more source

Cosmological gravitational particle production of massive spin-2 particles

open access: yesJournal of High Energy Physics, 2023
The phenomenon of cosmological gravitational particle production (CGPP) is expected to occur during the period of inflation and the transition into a hot big bang cosmology.
Edward W. Kolb   +3 more
doaj   +1 more source

Axions - Motivation, limits and searches [PDF]

open access: yes, 2006
The axion solution of the strong CP problem provides a number of possible windows to physics beyond the standard model, notably in the form of searches for solar axions and for galactic axion dark matter, but in a broader context also inspires searches ...
Raffelt, Georg G.
core   +2 more sources

Transcriptional regulation of neuropeptide receptors underlies context‐dependent adaptation in Drosophila melanogaster

open access: yesFEBS Open Bio, EarlyView.
Under environmental changes, the expression level of neuropeptide (NP) and neuropeptide receptor (NPR) genes changes to confer context‐dependent adaptation to the model organism Drosophila melanogaster. Through finding more regulatory elements in the NPR genes in comparison with their ligands (NPs), we found that NPR‐biased transcriptional regulation ...
SeungHeui Ryu   +6 more
wiley   +1 more source

A new life for sterile neutrinos: resolving inconsistencies using hot dark matter [PDF]

open access: yes, 2013
Within the standard ΛCDM model of cosmology, the recent Planck measurements have shown discrepancies with other observations, e.g., measurements of the current expansion rate H0, the galaxy shear power spectrum and counts of galaxy clusters. We show that
J. Hamann, Jasper Hasenkamp
semanticscholar   +1 more source

Axionic hot dark matter in the hadronic axion window [PDF]

open access: yesPhysics Letters B, 1998
Mixed dark matter scenario can reconcile the COBE data and the observed large scale structure. So far the massive neutrino with a mass of a few eV has been the only discussed candidate for the hot dark matter component. We point out that the hadronic axion in the so-called hadronic axion window, f_a \sim 10^6 GeV, is a perfect candidate as hot dark ...
Hitoshi Murayama   +2 more
openaire   +5 more sources

Mixed dark matter with low-mass bosons [PDF]

open access: yes, 1996
We calculate the linear power spectrum for a range of mixed dark matter (MDM) models assuming a massive (few eV) boson, $\phi$, instead of a neutrino as the hot component.
Larsen, Georg B., Madsen, Jes
core   +3 more sources

Development of Aluminum Scandium Alloys for Hydrogen Storage Valves

open access: yesAdvanced Engineering Materials, EarlyView.
Different aluminum alloy series and various aluminum‐scandium alloys with differing Sc and Zr levels are evaluated for use in hydrogen storage valve production. The alloys undergo hardness testing, optical microscopy, and tensile strength analysis, with hardening behavior studied under varying conditions.
Francisco García‐Moreno   +4 more
wiley   +1 more source

Astronomical Signatures of Dark Matter

open access: yesAdvances in High Energy Physics, 2014
Several independent astronomical observations in different wavelength bands reveal the existence of much larger quantities of matter than what we would deduce from assuming a solar mass to light ratio. They are very high velocities of individual galaxies
Paul Gorenstein, Wallace Tucker
doaj   +1 more source

That Raw and Ancient Cold: On Graham Harman’s Recasting of Archaeology

open access: yesOpen Philosophy, 2021
This is a comment to Graham Harman’s 2019 response to an article by Þóra Pétursdóttir and Bjørnar Olsen (2018) in which they propose that a materially grounded, archaeological perspective might complement Harman’s historical approach in Immaterialism ...
Sørensen Tim Flohr
doaj   +1 more source

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