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Hot-Melt Extrusion: a Roadmap for Product Development
AAPS PharmSciTech, 2021Hot-melt extrusion has found extensive application as a feasible pharmaceutical technological option over recent years. HME applications include solubility enhancement, taste masking, and sustained drug release. As bioavailability enhancement is a hot topic of today's science, one of the main applications of HME is centered on amorphous solid ...
Marta F, Simões +2 more
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Fusion Engineering and Design, 2015
Abstract Be–30.8 wt.%Ti powder mixture was extruded in copper and steel containers at 700 and 900 °C, respectively. In both cases, achieved extrusion ratio was 7:1. Investigations of microstructure of manufactured Be–Ti rods revealed that processing temperature has a great influence on the metal flow during the extrusion as well as formation of ...
Kurinskiy, P. +3 more
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Abstract Be–30.8 wt.%Ti powder mixture was extruded in copper and steel containers at 700 and 900 °C, respectively. In both cases, achieved extrusion ratio was 7:1. Investigations of microstructure of manufactured Be–Ti rods revealed that processing temperature has a great influence on the metal flow during the extrusion as well as formation of ...
Kurinskiy, P. +3 more
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Study on hot extrusion of tubes
Journal of Materials Processing Technology, 1997Abstract In this study, a numerical simulation model for forward hot extrusion processes of tube is developed by combining the upper bound method with the finite difference method. It is proposed to predict the deformation behaviors and forming load during the extrusion process.
Hsiang, S. H., Liao, C. S.
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2005
Abstract Hot extrusion is a process in which wrought parts are formed by forcing a heated billet through a shaped die opening. This article discusses nonlubricated and lubricated hot extrusion. The two nonlubricated hot extrusion methods are forward or direct extrusion and backward or indirect extrusion.
Frank F. Kraft, Jay S. Gunasekera
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Abstract Hot extrusion is a process in which wrought parts are formed by forcing a heated billet through a shaped die opening. This article discusses nonlubricated and lubricated hot extrusion. The two nonlubricated hot extrusion methods are forward or direct extrusion and backward or indirect extrusion.
Frank F. Kraft, Jay S. Gunasekera
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2007
The paper focuses on the main scientific problems related to hot metal extrusion of thin walled tube, strip and sections, covering analytical approach, 2D- and 3D-numerical simulation and experimental validation. The main physical phenomena and parameter estimation related to thermo-mechanical constitutive equations, shear localization, bearing channel,
Per Thomas Moe +2 more
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The paper focuses on the main scientific problems related to hot metal extrusion of thin walled tube, strip and sections, covering analytical approach, 2D- and 3D-numerical simulation and experimental validation. The main physical phenomena and parameter estimation related to thermo-mechanical constitutive equations, shear localization, bearing channel,
Per Thomas Moe +2 more
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Hot Melt Extrusion: A Paradigm–Changing Technology
Recent Advances in Drug Delivery and Formulation, 2023Abstract: Over the last few decades, hot melt extrusion (HME) has found extensive adaptability and utility as a viable drug delivery option in the pharmaceutical industry. HME has already been validated as a robust, novel technique mainly used for the correction of solubility and bioavailability of poorly soluble drugs.
Vaibhav G. Bhamare, Ravindra K. Kamble
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Ceska a Slovenska farmacie : casopis Ceske farmaceuticke spolecnosti a Slovenske farmaceuticke spolecnosti, 2012
Hot-melt extrusion (HME), originally coming from plastic industry, becomes at present an interesting technology also in the pharmaceutical field. The number of drugs with poor solubility and also bioavailability is increasing. In addition, most of the organic drugs are exhibiting polymorphism.
Salandová, Jana, Rabišková, Miloslava
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Hot-melt extrusion (HME), originally coming from plastic industry, becomes at present an interesting technology also in the pharmaceutical field. The number of drugs with poor solubility and also bioavailability is increasing. In addition, most of the organic drugs are exhibiting polymorphism.
Salandová, Jana, Rabišková, Miloslava
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Hot Hydrostatic Extrusion of Steel
1980Three kinds of steel, 0.40% carbon steel, Cr-Mo case hardening steel and 304 stainless steel, are hydrostatically extruded at high temperatures up to 1300°C.
M. Nishihara +4 more
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THE HOT EXTRUSION OF METAL POWDERS
Powder Metallurgy, 1964AbstractThe procedure of consolidating metal powders by isostatic compaction, canning, and hot extrusion is described. The properties of a number of nickel. base alloys and stainless steels prepared by this method are given.It is concluded that, even when no precautions are taken to eliminate air (oxygen) from the canned billet, the resulting oxide ...
C. R. SHAKESPEARE, D. A. OLIVER
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Hot Extrusion of Aluminum Chips
2012The process of hot extrusion is a promising approach for the direct recycling of aluminum machining chips to aluminum profiles. The presented technology is capable of saving energy, as remelting of aluminum chips can be avoided. Depending on the deformation route and process parameters, the chip-based aluminum extradates showed mechanical properties ...
A. Erman Tekkaya +3 more
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