Results 31 to 40 of about 131,708 (265)
Study on Hot Diaphragm Forming Process of CCF300/5228A Composites
MATEC Web of Conferences, 2017 In this paper, the hot diaphragm forming process of CCF300/5228A composite was studied through self-developed hot diaphragm forming equipment. CCF300/5228A prepreg for the hot diaphragm forming process was modified.
Yan Li, An Xuefeng
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pH‐mediated activation of the lysosomal arginine sensor SLC38A9
FEBS Letters, EarlyView.Cells monitor nutrient levels via the lysosomal transporter SLC38A9 to activate the mechanistic target of rapamycin complex 1 (mTORC1). This study reveals that SLC38A9 function is regulated by pH. We identified histidine 544 as a critical pH sensor that undergoes conformational changes to control amino acid efflux from lysosomes; therefore, it ...
Xuelang Mu, Ampon Sae Her, Tamir Gonen
wiley +1 more source
The ubiquitin‐proteasome system and autophagy as guardians of the cellular proteome
FEBS Letters, EarlyView.This Perspective covers the three principles governing the crosstalk between the ubiquitin‐proteasome system and autophagy in cellular proteostasis: (1) a shared ubiquitin code routing substrates via shuttle factors or autophagy receptors; (2) spatial compartmentalization into phase‐separated degradation hubs and organelle‐specific modules (exemplified
Ivan Dikic
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Journal of Materials Research and TechnologyThe complex deformation behavior would result in surface roughening such as orange peel defect during the hydroforming process of aluminum alloy tubular parts.
Shiqiang Zhu +3 more
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Case Studies in Structural Engineering, 2016 AbstractThis paper presents a comparative experimental study on the physical, chemical and mechanical properties of indirectly formed hot-formed, hot-finished and cold-formed structural steel rectangular hollow sections. Characteristic geometrical parameters and chemical compositions are examined to investigate the physical and chemical differences ...
Zhang, Xing-Zhao +3 more
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FEBS Letters, EarlyView.An unexpected alternative interaction site for ethyl viologen was identified in formate dehydrogenase 1 from Methylorubrum extorquens. Combined mutagenesis, kinetic analysis, and docking revealed that aromatic residues near an iron–sulfur cluster enable flavin mononucleotide‐independent electron transfer, offering a framework for engineering improved ...
Eleni G. Poloniataki, Yong Hwan Kim
wiley +1 more source
Towards Damage Controlled Hot Forming [PDF]
Applied Mechanics and Materials, 2018 Metal forming processes may induce internal damage in the form of voids in the workpiece under unfavorable deformation conditions. Controlling the amount of damage induced by metal forming operations may increase service performance of the produced parts. Damage is crucial in high-performance components of limited workability such as jet engine turbine
Markus Bambach +2 more
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PARP inhibitors induce a senescence phenotype in non‐small cell lung carcinoma cell lines
FEBS Open Bio, EarlyView.Talazoparib is the most potent inducer of senescence among different PARP1 inhibitors in human NSCLC cells. In the absence of PARP, no senescence phenotype was observed, demonstrating that PARP1 is necessary for the induction of senescence by this inhibitor.
Camille Huart +7 more
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Advances in Industrial and Manufacturing EngineeringWhile hydroforming of titanium alloy at room temperature is difficult due to its high strength, low hardening capacity, and significant springback, it is typically deformed into desired shape under high-temperature conditions exceeding 500°C, which ...
Xiao-Lei Cui +3 more
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Characterisation and modelling of the flow behaviour of a medium manganese steel for hot forming [PDF]
MATEC Web of ConferencesMedium manganese steels offer a wide range of advantages in hot forming compared to conventional boron steels such as lower heating temperatures and critical quenching rates.
Althaus Philipp +4 more
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