Results 31 to 40 of about 49,952 (245)

Optimization of thermal deformation process parameters of 2219 Al matrix composites

open access: yesHeliyon
To investigate the deformation behavior and optimize the hot processing parameters for 2219 aluminum matrix composite, the constitutive equation and hot processing maps were established.
Jing Wang   +3 more
doaj   +1 more source

Evaluation of Hot Workability of Nickel-Based Superalloy Using Activation Energy Map and Processing Maps [PDF]

open access: yesMaterials, 2020
The stress-strain curves for nickel-based superalloy were obtained from isothermal hot compression tests at a wide range of deformation temperatures and strain rates. The material constants and deformation activation energy of the investigated superalloy were calculated.
Oleksandr Lypchanskyi   +4 more
openaire   +2 more sources

Inhibiting stearoyl‐CoA desaturase suppresses bone metastatic prostate cancer by modulating cellular stress, mTOR signaling, and DNA damage response

open access: yesFEBS Letters, EarlyView.
Bone metastasis in prostate cancer (PCa) patients is a clinical hurdle due to the poor understanding of the supportive bone microenvironment. Here, we identify stearoyl‐CoA desaturase (SCD) as a tumor‐promoting enzyme and potential therapeutic target in bone metastatic PCa.
Alexis Wilson   +7 more
wiley   +1 more source

EVALUATING HOT DEFORMATION BEHAVIOR OF W360 TOOL STEEL BY HOT COMPRESSION TEST

open access: yesJournal of Advanced Materials in Engineering, 2021
In this research, the hot deformation behavior of W360 tool steel was investigated using hot compression test at 1000-1200°C and strain rates of 0.001, 0.01, 0.1, and 1 s-1. According to the results, dynamic recrystallization was found the most important
R. Amirarsalani   +2 more
doaj  

Hot Deformation Behavior and Microstructure Evolution of 2219/TiB2 Al-matrix Composite [PDF]

open access: yesMaterials Research, 2020
Hot compression tests for 2219/TiB2 Al-matrix composite were conducted on a Gleeble-3500 isothermal simulator in the temperature range of 300~500°C and strain rates of 0.01, 0.1, 1, 10s-1 to obtain true stress strain curves.
Wang Jing, Liang Qiang, Li Ping
doaj   +2 more sources

RaMBat: Accurate identification of medulloblastoma subtypes from diverse data sources with severe batch effects

open access: yesMolecular Oncology, EarlyView.
To integrate multiple transcriptomics data with severe batch effects for identifying MB subtypes, we developed a novel and accurate computational method named RaMBat, which leveraged subtype‐specific gene expression ranking information instead of absolute gene expression levels to address batch effects of diverse data sources.
Mengtao Sun, Jieqiong Wang, Shibiao Wan
wiley   +1 more source

Numerical Simulation of Crack Condition in Forging Products of M50 Bearing Steel Based on Processing Map Theory

open access: yesMetals, 2023
The microstructure of forged products significantly impacts their properties, and defects or carbide distribution are not visible to the naked eye.
Joonhee Park   +3 more
doaj   +1 more source

Pathogenic Neurofibromatosis type 1 gene variants in tumors of non‐NF1 patients and role of R1276

open access: yesFEBS Open Bio, EarlyView.
Somatic variants of the neurofibromatosis type 1 (NF1) gene occur across neoplasms without clinical manifestation of the disease NF1. We identified emerging somatic pathogenic NF1 variants and hotspots, for example, at the arginine finger 1276. Those missense variants provide fundamental information about neurofibromin's role in cancer.
Mareike Selig   +7 more
wiley   +1 more source

Hot Deformation Behavior and Processing Map of 25Cr2Ni2MoV Steel

open access: yesMetals
This study investigates the hot deformation behavior of electroslag remelted (ESR) 25Cr2Ni2MoV steel, focusing on the effects of deformation temperature and strain rate on flow stress, microstructure evolution, and dynamic recrystallization (DRX ...
Yong Wang   +4 more
doaj   +1 more source

Microstructure, Hot Deformation Behavior, and Textural Evolution of Mg-3Sn-2Al-1Zn-0.6Nd Alloy

open access: yesMetals, 2022
To prepare wrought magnesium alloys with excellent plastic deformation properties, Mg-3Sn-2Al-1Zn-0.6Nd alloys were prepared. A hot compression test of Mg-3Sn-2Al-1Zn-0.6Nd alloy was carried out on a thermo-mechanical simulator.
Yuhang Guo   +4 more
doaj   +1 more source

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