Results 41 to 50 of about 5,550,983 (250)

PANoptosis in the pathogenesis of myelodysplastic syndromes

open access: yesMolecular Oncology, EarlyView.
PANoptosis, a combination of three types of programmed cell death, is mediated by a large protein complex called a PANoptosome. In healthy bone marrow hematopoietic cells, PANoptosis is restricted by inhibitory signaling. In MDS, bone marrow cells become sensitive to the PANoptotic stimuli due to the aberrant inactivation of inhibitory signaling or ...
Rohit Thalla   +4 more
wiley   +1 more source

Green Map Flushing Meadow Queens NY

open access: yes, 2005
A map of Flushing Meadows Corona Park in Queens, NY, site of two world fairs (1939 and 1964) currently home to a number of recreation facilities and green space.
Green Map System (Firm)
core   +1 more source

Deformation behavior, microstructure characterization, and dynamic recrystallization mechanism of Au-7.5Ni-1.5Cu alloy

open access: yesMaterials & Design
The application of Au-based alloys in precision instruments components has achieved good results as electric contact materials. In order to investigate the hot processing of Au-based alloys, the hot deformation behavior and dynamic recrystallization (DRX)
Xiaoyi Pu   +7 more
doaj   +1 more source

Somatostatin receptor 4 (SSTR4) is a tumor suppressor in cutaneous and head & neck squamous cell carcinomas

open access: yesMolecular Oncology, EarlyView.
This study identifies somatostatin receptor 4 (Sstr4) as a critical tumor suppressor against skin and head/neck cancers (HNSCC, cSCC, and BCC). The loss of Sstr4 removes a check on cell growth, causing hyperactivation of the MAPK‐ERK signaling pathway (↑).
Ali Taqvi   +6 more
wiley   +1 more source

EVALUATING HOT DEFORMATION BEHAVIOR OF W360 TOOL STEEL BY HOT COMPRESSION TEST

open access: yesJournal of Advanced Materials in Engineering, 2021
In this research, the hot deformation behavior of W360 tool steel was investigated using hot compression test at 1000-1200°C and strain rates of 0.001, 0.01, 0.1, and 1 s-1. According to the results, dynamic recrystallization was found the most important
R. Amirarsalani   +2 more
doaj  

p190A/ARHGAP35 and p190B/ARHGAP5 proteins in endometrial cancer: a novel cancer‐relevant paralog interplay

open access: yesMolecular Oncology, EarlyView.
This study identifies ARHGAP5, in addition to the frequently mutated ARHGAP35, as significantly mutated in endometrial cancer. Mutations in both genes co‐occur and are associated with their correlated downregulation. Functional CRISPR studies show that both paralogs regulate similar pathways, including actin cytoskeleton organization.
Mathilde Pinault   +12 more
wiley   +1 more source

Community Green Map Detroit

open access: yes, 2003
A map of a small area of Detroit done by children, which includes descriptions and photographs of the community gathering that produced the ...
Detroit Green Map Team
core   +1 more source

Flow behavior and processing map of newly developed ECO-AlMag8 alloy during hot compression

open access: yesResults in Engineering
The flow behavior and processing map of ECO-AlMg8 alloy are investigated by hot compression of cylindrical samples machined from homogenized direct-chill cast billets at temperatures ranging from 300–450 °C and strain rates of 0.001 to 1 s⁻¹ using a ...
Majid Seyed Salehi   +5 more
doaj   +1 more source

An investigation of hot deformation behavior of Zn–22Al alloy and development of its processing maps during isothermal compression

open access: yesJournal of Materials Research and Technology, 2021
In this paper, the hot deformation behavior of Zn–22Al alloy was investigated by performing hot compression tests under different deformation conditions. The Arrhenius-type constitutive model was developed and the constants were determined for this alloy.
H. Mohammadi   +4 more
doaj   +1 more source

Single‐molecule DNA flow‐stretch assays for high‐throughput DNA–protein interaction studies

open access: yesFEBS Open Bio, EarlyView.
We describe an optimised single‐molecule DNA flow‐stretch assay that visualises DNA–protein interactions in real time. Linear DNA fragments are tethered to a surface and stretched by buffer flow for fluorescence imaging. Using λ and φX174 DNA, this protocol enhances reproducibility and accessibility, providing a versatile approach for studying diverse ...
Ayush Kumar Ganguli   +8 more
wiley   +1 more source

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