Results 61 to 70 of about 52,963 (289)

YlmG1 is localized exclusively to the chloroplast envelope membrane and is involved in preprotein translocation in Arabidopsis thaliana

FEBS Open Bio, EarlyView.
Cytosolically synthesized chloroplast preproteins are translocated across the outer and inner envelope membranes through translocons called TOC and TIC, respectively. In green algae and plants, the TIC core is composed of essential membrane proteins, Tic12, Tic20, and Tic214.
Mengyi Li, Xueyang Zhao, Masato Nakai
wiley   +1 more source

Deformation behavior, microstructure characterization, and dynamic recrystallization mechanism of Au-7.5Ni-1.5Cu alloy

Materials & Design
The application of Au-based alloys in precision instruments components has achieved good results as electric contact materials. In order to investigate the hot processing of Au-based alloys, the hot deformation behavior and dynamic recrystallization (DRX)
Xiaoyi Pu, Mingrong Qiao, Yu Zhang, Hong Xu, Haidong Niu, Yu Hong, Han Xiao, Haijun Wu   +7 more
doaj   +1 more source

Microstructure, Hot Deformation Behavior, and Textural Evolution of Mg-3Sn-2Al-1Zn-0.6Nd Alloy

Metals, 2022
To prepare wrought magnesium alloys with excellent plastic deformation properties, Mg-3Sn-2Al-1Zn-0.6Nd alloys were prepared. A hot compression test of Mg-3Sn-2Al-1Zn-0.6Nd alloy was carried out on a thermo-mechanical simulator.
Yuhang Guo, Yibo Dai, Pan Chen, Qianhao Zang, Zhenya Zhang   +4 more
doaj   +1 more source

Identifying transcription factors controlling the basal expression of human MRP4 highlights a substantial role for Sp1

FEBS Open Bio, EarlyView.
The MRP4 transporter exports several drugs and signaling molecules. Here, we identified key promoter elements regulating basal MRP4 expression. Using reporter assays, we defined a conserved region with essential Sp1 and contributory Ets sites, which controlled basal MRP4 expression.
Debora Singer, Angelique Kragl, Katrin Ziems, Juliane Glaubitz, Sophie Grammbauer, Susanne Hildebrandt, Mladen V. Tzvetkov, Gabriele Jedlitschky   +7 more
wiley   +1 more source

Natural Products as Geroprotective Modulators in Diabetic Nephropathy: A Mechanistic Framework Integrating Aging Hallmarks and the AMPK–SIRT1–Nrf2 Axis

Aging and Cancer, EarlyView.
Natural products target the aging kidney in diabetic nephropathy by restoring the AMPK–SIRT1–Nrf2 axis, reducing oxidative stress, inflammation, fibrosis, and cellular senescence while enhancing mitochondrial biogenesis and antioxidant defenses.
Sherif Hamidu, Latif Adams, Eunice Ampem‐Danso, Justice Kumi, Abigail Aning, Fatima Hamidu, Mustapha Abdul Mumin Mohammed, Ayuba Nii Darku Ankrah, Seth Kwabena Amponsah   +8 more
wiley   +1 more source

Investigation on hot deformation behavior of P/M Ni-base superalloy FGH96 by using processing maps

, 2010
The hot deformation behavior of a powder metallurgy (P/M) Ni-base superalloy FGH96 was investigated at the temperature (T) of 1050-1140°C, strain rate (ε̇) of 0.002-1.0s-1, and the height reduction of 20-50% via isothermal hot compression experiment. The
Xie, X, Ning, Y, Fu, MW, Zekun Yao, Yao, Z, Guo, H, Li, H, Yongquan Ning, M.W. Fu, Hui li, Hongzhen Guo, Xinghua Xie   +11 more
core   +1 more source

Vestibular Patient Journey: Insights From Vestibular Disorders Association (VeDA) Registry

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Vestibular symptoms impose a high burden of disability. Understanding real‐world diagnostic and treatment pathways can identify care gaps and guide interventions. We aimed to characterize symptom profiles, diagnostic trends, provider involvement, and treatment patterns in vestibular disorders.
Ali Rafati, Sami I. Nassar, Shaun A. Nguyen, Patricia L. Gerend, Michael C. Schubert, Michael T. Teixido, Frederick A. Godley, Joel A. Goebel, Cynthia A. Ryan, Habib G. Rizk, Amir Kheradmand   +10 more
wiley   +1 more source

Epilepsy‐Associated Variants of a Single SCN1A Codon Exhibit Divergent Functional Properties

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Pathogenic variants in SCN1A, which encodes the voltage‐gated sodium channel NaV1.1, are associated with multiple epilepsy syndromes exhibiting a range of clinical severity. SCN1A variants are reported in different syndromes, including Dravet syndrome, which is associated with loss‐of‐function, whereas neonatal/infantile‐onset ...
Lanie N. Liebovitz, Christopher H. Thompson, Linda C. Laux, Alfred L. George Jr.   +3 more
wiley   +1 more source

Hot Workability for a Ti-Nb IF Steel in Ferrite Area

Teshugang, 2008
According to hot simulation test results by Gleeble 1500D machine, the analytic expression between flow peak stress σpand Zener-Hollomon factor Z ( T, ε ) for Ti-Nb IF ( interstitial atom free) steel (0. 005C, 0. 055Al, 0. 01 Nb, 0.
张鹏, 汪凌云, 李伟
doaj  

An Improved Arrhenius Constitutive Model and Three-Dimensional Processing Map of a Solution-Treated Ni-Based Superalloy

High Temperature Materials and Processes, 2016
The hot deformation behaviors of a solution-treated Ni-based superalloy are investigated by hot compression tests over wide ranges of strain rate and forming temperature.
Li Hong-Bin, Feng Yun-Li
doaj   +1 more source