Hot springs have been investigated since the XIX century, but isolation and examination of their thermophilic microbial inhabitants did not start until the 1950s. Many thermophilic microorganisms and their viruses have since been discovered, although the
Olalla López-López +2 more
doaj +4 more sources
Association between hot spring residency and dry eye disease: a crossover gene–environment interaction (GxE) study in Taiwan [PDF]
Background/aims The advent of genetic biobanking has powered gene-environment interaction (GxE) studies in various disease contexts. Therefore, we aimed to discover novel GxE effects that address hot spring residency as a risk to inconspicuous disease ...
Hsin-Yu Wu +18 more
doaj +2 more sources
A Hot-Spring Water Improves Inflammatory Conditions in an Injury-Induced Atopic Dermatitis Mouse Model by Regulating Skin Barrier Function [PDF]
Background: Atopic dermatitis (AD) is a common inflammatory skin condition in which skin barrier function plays a crucial role. Hot spring water is known for its beneficial effects on skin health.
Yoko Naito +9 more
doaj +2 more sources
Night-Time Hot Spring Bathing Is Associated with a Lower Systolic Blood Pressure among Japanese Older Adults: A Single-Institution Retrospective Cohort Study [PDF]
Hot spring bathing is practiced to help manage hypertension. We retrospectively investigated the effects of hot spring bathing on hypertension with the aim of identifying a novel approach to prevent and manage hypertension.
Satoshi Yamasaki +3 more
doaj +2 more sources
Myoban hot spring bathing improves gut microbiota composition and short-chain fatty acid levels: a pilot study [PDF]
Background: Although many studies have reported the therapeutic effects of hot spring bathing on various diseases, its influence on healthy individuals is not well understood.
Midori Takeda +2 more
doaj +2 more sources
Geochemical Characteristics of Three Hot Springs from Western Thailand
At present a total of 118 hot springs are distributed throughout Thailand. Several studies with a focus on high-temperature hot springs related to geothermal resources were conducted in the northern and southern part of the country.
Thiwat Rattanawong +3 more
doaj +7 more sources
Water budget of Lake Ashinoko, the origin of Hakone thermal waters
Study region: Lake Ashinoko in the Hakone caldera is located about 100 km southwest of Tokyo, the capital of Japan. Hakone is a world-famous resort that more than 20 million tourists visit every year to enjoy various kinds of hot springs and spectacular ...
Kazuhiro Itadera, Akio Yoshida
doaj +1 more source
Carbonate ion-enriched hot spring water promotes skin wound healing in nude rats. [PDF]
Hot spring or hot spa bathing (Onsen) is a traditional therapy for the treatment of certain ailments. There is a common belief that hot spring bathing has therapeutic effects for wound healing, yet the underlying molecular mechanisms remain unclear.
Jingyan Liang +5 more
doaj +1 more source
Comparative analysis of bacterial diversity in two hot springs in Hefei, China
Hot springs are extreme ecological environments of microbes. The study is the first comparative analysis of bacterial diversity of Tangchi and Bantang hot spring water samples collected in Hefei, China, which is conducive to the further development and ...
Feng-Qin Zhang, Jun Liu, Xiao-Ju Chen
doaj +1 more source
Factors contributing to tourism demand at major Japanese hot springs.
Hot springs are a major tourism resource in nature-based tourism, and the hot springs market is one of the biggest sectors in wellness tourism markets. In the present study, we examine factors contributing to tourism demand for major hot spring resorts ...
Nagi Medai +3 more
doaj +2 more sources

