Results 61 to 70 of about 22,167,605 (308)

Hotspot analysis and prediction for mobile networking applications

Annals of Telecommunications
Understanding the dynamics of mobile traffic is highly valuable for a variety of fields, such as transportation and networking. In particular, analyzing hotspots, i.e., areas presenting an increased popularity at certain times, is crucial for adequate planning and management operations. Yet, despite its importance, we lack today a precise definition of
Djuikom Foka, Gwladys Ornella, Mishra, Sachit, Stanica, Razvan, Naboulsi, Diala   +3 more
openaire   +3 more sources

ADP‐ribosylation: An emerging regulator of the epigenome

Molecular Oncology, EarlyView.
ADP‐ribosylation has emerged as a dynamic epigenetic signaling mechanism that modifies histones and chromatin‐associated proteins. Through coordinated PARylation and MARylation, it integrates with other histone modifications to regulate chromatin structure, transcription factor activity, and gene expression, influencing genome function and disease ...
Cristel V. Camacho, Chenqian Liu, W. Lee Kraus   +2 more
wiley   +1 more source

The VHL tumor suppressor at the crossroad of protein folding, aggregation, and cancer

Molecular Oncology, EarlyView.
Mutations, environmental stress, and chaperone dysfunction can destabilize pVHL, promoting its conversion from the native folded state into amyloid‐like assemblies. This transition may contribute to protein storage, cell dormancy, survival, and drug resistance.
Lara Abad, Silvio Carlo Ermanno Tosatto, Emanuela Leonardi   +2 more
wiley   +1 more source

Visualization and hotspot analysis of CAR‐T research based on CiteSpace

Precision Medical Sciences
Through bibliometric analysis of CAR‐T research hotspots and development trends, a reference is provided to promote cutting‐edge research on CAR‐T. Acquired research literature on CAR‐T cells from the Web of Science Core Collection (WOSCC) as of November
Kejin Li, Yue Teng, Weiyan Tang, Liuliu Zhang, Xiaoxu Zhi, Wenjuan Li, Jianqiu Wu   +6 more
doaj   +1 more source

Spatio-Temporal Analysis of Dengue in the Philippines: The Case of South Cotabato

Recoletos Multidisciplinary Research Journal
Background: South Cotabato Province in the Philippines has experienced recurring dengue outbreaks, necessitating spatio-temporal analysis to guide effective prevention and control strategies. Methods: This study analyzed 4,004 reported dengue cases from
Jessiryl Ygoña, Eveyth Deligero, Roel Ceballos   +2 more
doaj   +1 more source

APOBEC3 activity and DNA polymerase‐ε deficiency are associated with distinct IDH1 R132 hotspot mutations

Molecular Oncology, EarlyView.
Isocitrate dehydrogenase 1 (IDH1) mutations are highly recurrent in multiple human cancer types, including cholangiocarcinoma and glioma. IDH1 R132C is the most common IDH1 mutation in cholangiocarcinoma and likely arises from APOBEC3A‐ or APOBEC3B‐mediated deamination.
Kelly E. Butler, Bilal A. Lone, Ecem Unal, A. Rouf Banday   +3 more
wiley   +1 more source

Simulation and attribution analysis of agricultural nitrogen non-point source pollution in Huang-Huai-Hai Plain based on the InVEST model

Frontiers in Environmental Science
The study of agricultural non-point source pollution (ANNSP) patterns and driving mechanisms is crucial for regional ecological management. This paper evaluates the sources of ANNSP in the Huang-Huai-Hai Plain for the years 2000, 2010, and 2020 using the
Ying Yu, Weiqiang Chen, Guangxing Ji, Yulong Guo, Yinan Chen, Siyu Sheng, Yaru Deng, Qianwen Weng   +7 more
doaj   +1 more source

Mobile Monitoring of Air Pollution Reveals Spatial and Temporal Variation in an Urban Landscape

Frontiers in Built Environment, 2021
Urban air pollution poses a major threat to human health. Understanding where and when urban air pollutant concentrations peak is essential for effective air quality management and sustainable urban development.
Lucas E. Cummings, Justin D. Stewart, Justin D. Stewart, Radley Reist, Kabindra M. Shakya, Peleg Kremer   +5 more
doaj   +1 more source

Bridging the gap: a genetically validated avian chorioallantoic membrane platform for investigation of spontaneous circulating tumor cells

Molecular Oncology, EarlyView.
We established the avian chorioallantoic membrane (CAM) assay as a scalable in vivo model for studying circulating tumor cells (CTCs). Human gastrointestinal tumors spontaneously released genetically validated CTCs that were detected across multiple platforms, demonstrating that the CAM model provides an accessible tool for investigating early cancer ...
Dennis Roth, Rui P. L. Neves, Julia Geheb, Christian Ballmeyer, Nathalie Gaßmann, Kiki C. Andree, Monica Sudarsanam, Christiane Driemel, Celine Örencik, Andrè Franken, Eslam Elmaghraby, Sven H. Loosen, Roderburg Christoph, Sebastian Schoelch, Hans Neubauer, Wolfram T. Knoefel, Nikolas H. Stoecklein, Georg Fluegen   +17 more
wiley   +1 more source

From Land Use Change to Ecosystem Service Sustainability: Multi-Scenario Projections for Urban Agglomerations in Arid Northwest China

Urban Science
Ecosystem services play a crucial role in sustaining human life, providing numerous benefits that are indispensable for our well-being. However, these vital functions are increasingly compromised by land use changes that have been instigated by human ...
Yusuyunjiang Mamitimin, Ailijiang Nuerla, Zaimire Abudushalamu, Meiling Huang   +3 more
doaj   +1 more source