Results 41 to 50 of about 27,015 (256)

Histone H3 Lysine 56 Acetylation Is Required for Formation of Normal Levels of Meiotic DNA Breaks in S. cerevisiae

Frontiers in Cell and Developmental Biology, 2020
Meiotic recombination is initiated by Spo11-catalyzed DNA double-strand breaks (DSBs) that are promoted by histone modifications and histone modifying enzymes. Herein we investigated the role of histone H3 lysine 56 acetylation (H3K56ac) located near the
Zsolt Karányi, Zsolt Karányi, Lilla Hornyák, Lóránt Székvölgyi   +3 more
doaj   +1 more source

ADP‐ribosylation: An emerging regulator of the epigenome

Molecular Oncology, EarlyView.
ADP‐ribosylation has emerged as a dynamic epigenetic signaling mechanism that modifies histones and chromatin‐associated proteins. Through coordinated PARylation and MARylation, it integrates with other histone modifications to regulate chromatin structure, transcription factor activity, and gene expression, influencing genome function and disease ...
Cristel V. Camacho, Chenqian Liu, W. Lee Kraus   +2 more
wiley   +1 more source

Small RNA pathways in mammalian oocytes

FEBS Open Bio, EarlyView.
Three distinct small RNA pathways operate in mammalian oocytes: RNAi interference (RNAi), the microRNA (miRNA) pathway, and the PIWI‐associated RNA (piRNA) pathway. These pathways use small RNAs to guide sequence‐specific repression and contribute to oocyte biology by targeting genes and mobile elements or appear insignificant since different ...
Petr Svoboda, Josef Pasulka
wiley   +1 more source

Aging Is a Key Driver for Adult Acute Myeloid Leukemia

Aging and Cancer, EarlyView.
Acute myeloid leukemia (AML) is a classical age‐related hematologic malignancy, and a key driver of AML is aging, which profoundly regulates intrinsic factors such as genomic instability, epigenetic reprogramming, and metabolic dysregulation, and alters bone marrow microenvironment.
Rong Yin, Haojian Zhang
wiley   +1 more source

Resilient Multi-UAV Collaborative Mapping: A Safety-Prioritized Scheduling Framework with Hierarchical Transmission

Drones
Multi-UAV collaborative mapping in communication-constrained indoor environments is often hampered by a trade-off between overall map refinement and the timely completion of safety-relevant shared regions.
Shu Wake, Zewei Jing, Lanxiang Hou, Jiayi Sun, Guanchong Niu, Liang Mao, Jie Li   +6 more
doaj   +1 more source

Mapping Brain Motor Functions Using Transcranial Magnetic Stimulation with a Volume Conductor Model and Electrophysiological Experiments

Brain Sciences, 2023
Transcranial magnetic stimulation (TMS) activates brain cells in a noninvasive manner and can be used for mapping brain motor functions. However, the complexity of the brain anatomy prevents the determination of the exact location of the stimulated sites,
Keigo Hikita, Jose Gomez-Tames, Akimasa Hirata   +2 more
doaj   +1 more source

Effectiveness of rTMS on Working Memory and Inhibitory Impairments in Patients With Post‐Stroke Executive Deficits

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Considerable efforts have been dedicated to developing effective treatments for post‐stroke executive impairment (PSEI), among which repetitive transcranial magnetic stimulation (rTMS) has shown great potential. This study aimed to investigate the therapeutic effects of high‐frequency rTMS on working memory (WM) and response ...
Mengting Lao, Rongwei Du, Zhujun Wang, Yang Gao, Meiling Cheng, Xianglong Wang, Wen Wu   +6 more
wiley   +1 more source

Electrophysiological sweet spot mapping in deep brain stimulation for Parkinson's disease patients

Brain Stimulation
Background: Subthalamic deep brain stimulation (STN-DBS) is a well-established therapy to treat Parkinson's disease (PD). However, the STN-DBS sub-target remains debated.
Jana Peeters, Tine Van Bogaert, Alexandra Boogers, Robin Gransier, Jan Wouters, Philippe De Vloo, Wim Vandenberghe, Michael T. Barbe, Veerle Visser-Vandewalle, Bart Nuttin, Till A. Dembek, Myles Mc Laughlin   +11 more
doaj   +1 more source

Crime Hotspot Detection and Monitoring Using Video Based Event Modeling and Mapping Techniques*

International Journal of Computational Intelligence Systems, 2017
This paper presents a new approach to crime hotspot detection and monitoring. The approach consists of three phases’ namely: video analysis, crime prediction and crime mapping.
Zou Beiji, Nurudeen Mohammed, Zhu Chengzhang, Zhao Rongchang   +3 more
doaj   +1 more source

Network Analysis Prioritizes DEWAX and ICE1 as the Candidate Genes for Major eQTL Hotspots in Seed Germination of Arabidopsis thaliana

G3: Genes, Genomes, Genetics, 2020
Seed germination is characterized by a constant change of gene expression across different time points. These changes are related to specific processes, which eventually determine the onset of seed germination.
Margi Hartanto, Ronny V. L. Joosen, Basten L. Snoek, Leo A. J. Willems, Mark G. Sterken, Dick de Ridder, Henk W. M. Hilhorst, Wilco Ligterink, Harm Nijveen   +8 more
doaj   +1 more source