Results 111 to 120 of about 1,668,878 (290)

SPHINX31 acts as a SRPK1 inhibitor targeting the ATR/DNA‐PKcs/CHK1 replicative checkpoint to inhibit cell growth in non‐small cell lung cancer

open access: yesMolecular Oncology, EarlyView.
The kinase SRPK1 directly interacts with the protein TOPBP1 and regulates the pre‐mRNA splicing of WIZ thereby contributing to the activation of the ATR/CHK1 replicative checkpoint in response to replicative stress. This allows cancer cells' genomic stability and survival.
Amani Shreim   +17 more
wiley   +1 more source

Idle Hour Nurseries [catalog]

open access: yes, 1922
192
Idle Hour Nurseries.   +1 more
core   +2 more sources

The Literacy Hour [PDF]

open access: yes
Literacy matters. One in five adults in the UK is not functionally literate and this has serious implications for their well-being and economic circumstances, as well as for national productivity.
Sandra McNally, Stephen Machin
core  

Cyclic azapeptide CD36 ligand attenuates cardiac injury and reduces long‐chain fatty acid accumulation after myocardial ischemia–reperfusion in mice

open access: yesFEBS Open Bio, EarlyView.
In a murine model of myocardial ischemia and reperfusion (MI/R), the CD36 azapeptide ligand MPE‐298 reduces cardiac injury and transiently lowers left ventricular long‐chain fatty acids (LCFAs) accumulation 3 h after reperfusion, accompanied by a decrease of oxidative stress and inflammation‐associated genes' expression in the heart and adipose tissue.
Jade Gauvin   +12 more
wiley   +1 more source

Buddhist Monk with Dr. Raymond Hour Photograph

open access: yes, 2013
Color photograph of Dr. Raymond Hour with a Buddhist Monk in Sala Chan (mulipurpose room) at Wat Buddhikaram-Utah Cambodian Buddhist Temple\u27s groundbreaking ...
Hour, Dr. Raymond
core  

Molecular characterization of covRS mutations in M1UK Streptococcus pyogenes

open access: yesFEBS Open Bio, EarlyView.
Group A Streptococcus (GAS) acquires covRS mutations driving a hypervirulent bacterial state, frequently associated with invasive disease‐like necrotizing fasciitis. We demonstrate that the newly emerged M1UK GAS lineage can also acquire these mutations.
Jarrad Pritchard   +12 more
wiley   +1 more source

Effects of 6% Tetrastarch and Lactated Ringer's Solution on Extravascular Lung Water and Markers of Acute Renal Injury in Hemorrhaged, Isoflurane‐Anesthetized Healthy Dogs

open access: yesJournal of Veterinary Internal Medicine, 2018
Background Tetrastarch can cause acute kidney injury (AKI) in humans with sepsis, but less likely to result in tissue edema than lactated Ringer's solution (LRS). Objectives Compare effects of volume replacement (VR) with LRS and 6% tetrastarch solution (
M.S. Diniz   +6 more
doaj   +1 more source

EIGHT HOUR JUBILEE MEDAL

open access: yes, 1916
This record was harvested from a previous catalogue system and will be withdrawn in 2025. Information in this record may be superseded or incomplete. Visit this record in UMA's new catalogue at: https://archives.library.unimelb.edu.au/nodes/view/65971One
Melbourne Eight Hour Day Anniversary Committee
core  

Evaluating the involvement of autolysosomes in the nuclear translocation of fluorescent proteins

open access: yesFEBS Open Bio, EarlyView.
Endogenously expressed fluorescent proteins can be degraded by autophagy and transported to cell nuclei via the nuclear pore complex. But in some cell lines, for example, HeLa cells which are positive for immunoreactivity of a receptor ligand, such as UCN I, in cell nuclei, fusion of autolysosome with the nuclear envelope is involved in the nuclear ...
Keiichi Ikeda
wiley   +1 more source

Risk factors for renal impairment in primary aldosteronism: a retrospective study

open access: yesFrontiers in Endocrinology
ObjectiveThis study aimed to investigate the risk factors associated with renal impairment among patients diagnosed with primary aldosteronism (PA).MethodsThis study enrolled 147 PA patients who were initially classified into hypokalemic (n=56) and ...
Shuitao Qin   +10 more
doaj   +1 more source

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