Results 41 to 50 of about 2,385,256 (313)

From mice to humans—divergent strategies for intestinal homeostasis and regeneration

open access: yesFEBS Letters, EarlyView.
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa   +2 more
wiley   +1 more source

Whittier House membership card for Aaron Reeves. Nationality is listed as "Negro."

open access: yes, 1938
This collection of Whittier House Boy's Club membership cards records children's names, parent's names, places of birth, nationalities, family members, occupations, church affiliations, and addresses.
Whittier House Boys Club
core   +1 more source

PARK(ing) time–How park deficiency affects the biological clock in a Drosophila model of Parkinson's disease

open access: yesFEBS Letters, EarlyView.
Drosophila park mutants serve as a model for Parkinson's disease. We used this strain to investigate the connection between oxidative stress and the circadian clock mechanism. We showed that increased oxidative stress affects the physiology of pacemaker cells, disrupting their daily structural plasticity. Lack of rhythmic signaling from pacemaker cells
Kamila Zientara   +3 more
wiley   +1 more source

Casa Gallinero: Concepción, Chile

open access: yesARQ, 2011
La casa Gallinero es parte de una serie de proyectos que trata de buscar alto nivel de eficiencia constructiva -entregada principalmente por la sistematización de sus elementos- para lograr casas de gran tamaño y muy bajo presupuesto.
Eduardo Castillo
doaj  

The Rural Borderland House: Functional‑Spatial and Ritual-Symbolic Specificities

open access: yesЖурнал Фронтирных Исследований
This publication reviews the monograph by Polish researcher and PhD in Architecture Magdalena Sulima, which addresses the topics of architectural and ceremonial specifics of traditional rural housing in border territories. under-studied in Russia: Sulima,
Anna Yu. Kazakova
doaj   +1 more source

Structural insights and therapeutic targets in Acinetobacter baumannii capsule biosynthesis

open access: yesFEBS Letters, EarlyView.
Hypervirulent KL49 A. baumannii's capsular polysaccharide contains the nonulosonic acid 8‐epi‐Leg5,7Ac2, synthesized by epimerization via ElaA, ElaB, and ElaC. Crystal structures of ElaA, ElaB, and ElaC reveal their role in CMP‐Leg5,7Ac2 synthesis and regioselective C8 epimerization.
Woo Cheol Lee   +7 more
wiley   +1 more source

Whittier House Boys Club card - Frank Russelio (Catholic-Italian)

open access: yes, 1936
This collection of Whittier House Boy's Club membership cards records children's names, parent's names, places of birth, nationalities, family members, occupations, church affiliations, and addresses. This membership card belonged to 21-year-old Italian
Whittier House Boys Club
core   +1 more source

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

open access: yesMolecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat   +8 more
wiley   +1 more source

A meeting place for faces and souls

open access: yesПроект Байкал
The function of architecture is to be a meeting place, signifying a contact in the realm of destinies. Cities, squares, intersections and houses are subjects of social and existential communication.
Александр Раппапорт
doaj   +1 more source

Le village lorrain du Moyen Âge à nos jours. Architecture et organisation spatiale des maisons

open access: yesArchéopages, 2015
Until preventive archaeology became established it was mainly geographers who considered villages and houses as suitable material for studying social changes. However, they worked on archival material and on what today’s villages could still reveal about
Franck Gérard
doaj   +1 more source

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