Results 51 to 60 of about 1,062,147 (264)

Fire simulation in house conditions [PDF]

Tehnika, 2016
Fire simulation presents very powerful, economic and safe way for determination of potential fire scenarious in particular object. Because the fire presents very unpredictable event, it is very important to ,as much is possible, predict its potential ...
Jevtić Radoje B.
doaj   +1 more source

An epithelial GPR35 isoform supports tumor‐associated transcriptional and metabolic phenotypes

FEBS Letters, EarlyView.
GPR35 generates two functionally distinct isoforms with previously unresolved roles. GPR35‐short mediates immune‐cell chemotaxis, while GPR35‐long is enriched in colorectal cancer epithelium, where it supports increased metabolism, proliferation, and tumor‐associated transcriptional programs.
Jørgen D. Rønneberg, Martine Hjeltnes, Josephine Krieger, Joshua E. Elias, Maria Stensland, Kristian Holm, Xiaojun Jiang, Chuki Khangsar, Tuula A. Nyman, Arthur Kaser, Johannes R. Hov, Tom H. Karlsen, Nicole C. Kaneider, Frode L. Jahnsen, Georg Schneditz   +14 more
wiley   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Keratin 19 as a prognostic marker and contributing factor of metastasis and chemoresistance in high‐grade serous ovarian cancer

Molecular Oncology, EarlyView.
Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch, Isabel Vogel, Sina Nokodian, Johanna Moeller, Antonia Blechschmidt, Vicky Hecht, Vanessa Kuentzel, Katharina Thiedig, Melissa Schwab, Oliver Schilling, Holger Bronger, Marion Kiechle, Viktor Magdolen, Tobias Dreyer   +13 more
wiley   +1 more source

Des maisons « comme des petits temples » ou la mise en scène de l’espace domestique réformé sous le régime de l’édit de Nantes

Les Dossiers du GRIHL
Talking about the everyday objects of Reformed religious dissent under the Edict of Nantes in France may seem like a rather daunting task. Yet one might well ask whether the "Religion of the Word," as Protestantism is often called, truly rejects all ...
Christabelle Thouin-Dieuaide
doaj   +1 more source

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

Molecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric, Line Bjørge, Martine Rott Lode, Cecilie Fredvik Torkildsen, Pia Aehnlich, Rammah Elnour, Daniela Elena Costea, Lars Andreas Akslen, Liv Cecilie Vestrheim Thomsen, Emmet McCormack, Katrin Kleinmanns   +10 more
wiley   +1 more source

Linguistic Realization of the Concept “House/Home” in Yu.V. Trifonov’s Discourse

Известия Южного федерального университета: Филологические науки, 2018
The increased attention of modern linguistic science to the questions of conceptualization of the surrounding world is due to the fact that V. von Humboldt’s ideas about the interrelation between the language and the character of the people are being ...
Dinara R. Valeeva
doaj   +1 more source

CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3

Molecular Oncology, EarlyView.
PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh, Nitzan Medina‐Itzhaki, Milena Chekov, Eden Gal‐Swisa, Roba Gabesh‐Wahabi, Inbar Savyon, Inna Naroditsky, Hilary A. Kenny, Basem Fares, Lina Korsensky, Einav Girsh, Liron Berger, Ruth Perets   +12 more
wiley   +1 more source

Aung San Suu Kyi and U.S. Policy toward Burma/Myanmar

Journal of Current Southeast Asian Affairs, 2010
No living foreigner has shaped contemporary U.S. attitudes toward a single country more than Aung San Suu Kyi. As the seemingly vulnerable international avatar of democracy, she has effectively determined the parameters of possible U.S.
David I. Steinberg
doaj  

Entre los principios y los fines. Ética y estética en el episodio El Tirano de la serie House

Revista de Medicina y Cine / Journal of Medicine and Movies, 2020
Este artículo profundiza en los acontecimientos narrados en el cuarto episodio de la sexta temporada de la serieHouse M.D. (título en inglés, en España es conocida como House o Dr. House). En él, el Doctor Chase se ve en el dilema de tratar a un dictador
Ignacio GAZTAKA EGUSKIZA
doaj