Results 71 to 80 of about 1,062,147 (264)
Pharmacological chromatin remodeling enhances response to estrogen therapy in ER+ breast cancer
Molecular Oncology, EarlyView.Estrogen therapy elicits clinical benefit in ~ 30% of patients with endocrine‐resistant estrogen receptor (ER)‐positive breast cancer. Based on findings that ER transcriptional activation underlies response to estrogen therapy, we tested the effects of epigenetic dysregulation via pharmacological inhibition of histone deacetylases (HDACi).
Anneka L. Johnson Thomas +16 more
wiley +1 more source
Royal Studies Journal, 2023 The reign of the Catholic Monarchs is possibly the most important reign and, therefore, the most studied in the history of our country. However, this reign had a defect in the form of its offspring, not because of the absence of children but because ...
Oscar Jimenez Molero +1 more
doaj
“Live in the House – and the House Will not Decline”
Concept: philosophy, religion, culture, 2019 .
openaire +3 more sources
Spatial biology in cancer epigenetics
Molecular Oncology, EarlyView.Spatial epigenomics combines molecular profiling with tissue architecture to reveal how gene regulation is organized within intact tissues. In cancer, these technologies uncover the mechanisms driving tumor heterogeneity and microenvironmental interactions, opening new opportunities for biomarker discovery and precision medicine.
Eva Crespo‐García, Manel Esteller
wiley +1 more source
Magallania, 2009 Se informa sobre el hallazgo de una forma arquitectónica elemental para uso como vivienda rural ocasional.The finding of an elemental architectonic form for use as occasional rural house is informed.
MATEO MARTINIC B
doaj
Devenir un « maître de maison » dans le Sud jordanien
Ateliers d'Anthropologie, 2015 How does one become a master of the house, a man capable of controlling a kinship network and a family space? This article approaches the logic of power and authority in a tribal area of southern Jordan through its spatial and corporeal dimensions.
Christine Jungen
doaj +1 more source
Theory of Housing, From Housing, About Housing [PDF]
Housing, Theory and Society, 2017 Four positions concerning theorising housing-related phenomena are discussed. (1) Theory of housing (v1): It is possible and desirable to construct a theory of housing to which all housing-related ...
openaire +1 more source
Raman‐based label‐free microscopic analysis of the pancreas in living zebrafish larvae
FEBS Open Bio, EarlyView.Forward stimulated Raman scattering (F‐SRS) and epi coherent anti‐Stokes Raman scattering (E‐CARS) allow label‐free discrimination of distinct subcellular structures in the pancreas of living zebrafish larvae. Given the straightforward applicability, we anticipate broad implementation of Raman microscopy in other organs and across various biomedical ...
Noura Faraj +3 more
wiley +1 more source
L. N. Tolstoy on the 20th-Century Estate: From the “Civilization of Machines” to a New Natural House of the Eastern Type [PDF]
Два века русской классикиThe article is devoted to the image of the estate and the house in L. N. Tolstoy’s legacy, especially in his later works. The research indicates that at the turn of the century and in the first decade of the 20th century, Tolstoy became an ardent ...
Valeria G. Andreeva
doaj +1 more source
Single‐molecule DNA flow‐stretch assays for high‐throughput DNA–protein interaction studies
FEBS Open Bio, EarlyView.We describe an optimised single‐molecule DNA flow‐stretch assay that visualises DNA–protein interactions in real time. Linear DNA fragments are tethered to a surface and stretched by buffer flow for fluorescence imaging. Using λ and φX174 DNA, this protocol enhances reproducibility and accessibility, providing a versatile approach for studying diverse ...
Ayush Kumar Ganguli +8 more
wiley +1 more source