Results 61 to 70 of about 1,062,147 (264)

Stimulator of interferon genes agonist augmented antitumor immunity of osimertinib in Egfr‐mutated lung cancer

open access: yesMolecular Oncology, EarlyView.
Combining osimertinib with the STING agonist ADU‐S100 activates innate and adaptive immunity to overcome the non‐inflamed microenvironment of Egfr‐mutant lung cancer. This combination increases NK and CD8+ T‐cell infiltration, associated with activation of the STING‐IRF3 pathway and local immunogenic cell death.
Jun Nishimura   +19 more
wiley   +1 more source

Tropical Gothic: Radiance Revisited

open access: yeseTropic: electronic journal of studies in the tropics, 2008
Directed by Rachel Perkins in 1998, Radiance is a film that deserves a sequel. The fates of Mae, Cressy and Nona after they head off up the road in Mae's old car is a cinematic mystery that intrigues me more the longer I live in North Queensland, the ...
Allison Craven
doaj   +1 more source

The House, the Home and the Housing Question

open access: yesDocomomo Journal, 2014
Housing is a central program in contemporary architectural production. Incorporating civilizing values of 19th century culture, the house arrives in the 20th century at the time notions of private space and domestic comfort come to the fore in Western Culture as values inseparable from the emergence of the family in domestic space: the home.
openaire   +3 more sources

USP29‐regulated noncanonical stabilization of the hypoxia‐inducible factor‐α in aggressive prostate cancer

open access: yesMolecular Oncology, EarlyView.
We identify USP29 as the only DUB mirroring CA9 expression, a marker of hypoxia and HIF pathway activation associated with PCA aggressiveness. USP29 stabilizes HIF‐1α and HIF‐2α via a noncanonical mechanism that is independent of PHD/pVHL activity yet relies on proteasomal regulation, establishing USP29 as a previously unrecognized regulator of hypoxic
Amelie S Schober   +16 more
wiley   +1 more source

ANALISIS MATEMATIS PENGARUH LOKASI RUMAH TERHADAP HARGA JUAL, LUAS RUMAH DAN JUMLAH KAMAR DENGAN MANOVA

open access: yesJurnal Lebesgue
A house is a building that functions as a residence or residence and a means of family development (Law No. 4 of 1992). Every community needs a house as a necessity. With so many people needing a place to live, house construction often occurs.
Annisa Nur Afifah Kusuma Sayekti   +2 more
doaj   +1 more source

Loss of proton‐sensing TDAG8 increases tumor progression in mouse models of colon cancer

open access: yesMolecular Oncology, EarlyView.
Loss of the pH‐sensing receptor TDAG8 accelerates colorectal cancer progression in mice. Animals lacking TDAG8 expression had increased tumor growth, DNA damage, and recruitment of tumor‐associated immune cells, including macrophages, neutrophils, and monocytes.
Ermanno Malagola   +11 more
wiley   +1 more source

Lo doméstico y lo público. Los espacios de sociabilidad de la ciudad de San Miguel de Tucumán a fines del siglo  XVIII y comienzos del siglo XIX

open access: yesNuevo mundo - Mundos Nuevos, 2010
The study of the sociability of the old regime takes the house as its main territorial expression. At the same time, the house was the main space of sociability and contact in the city at a time when public and private were not clearly distinguished ...
Romina Zamora
doaj   +1 more source

Epigenetic silencing of the liver‐specific lncRNA LUNAR promotes liver cancer progression via NOTCH activation

open access: yesMolecular Oncology, EarlyView.
LUNAR is a liver‐specific long noncoding RNA (lncRNA) that is highly expressed in normal liver but becomes epigenetically silenced in hepatocellular carcinoma through promoter hypermethylation. Loss of LUNAR is associated with NOTCH activation, epithelial–mesenchymal transition, and metastasis, whereas restoring LUNAR restrains metastatic progression ...
Se Ha Jang   +9 more
wiley   +1 more source

Мифологические персонажи культурного пространства в севернорусском и норвежском фольклоре (типологические аспекты)

open access: yesPoznańskie Studia Slawistyczne, 2012
Mythological characters of the cultural space in the folklore of the Russian North and Norway (typological aspects)is a comparative analysis of spirits of house that exist in the cultures  of  both  countries.  For  comparison,  we  examined  different 
Наталья Дранникова
doaj   +1 more source

Poetic landscapes of Wilhelm Przeczek

open access: yesActa Universitatis Lodziensis. Folia Litteraria Polonica, 2020
Wilhelm Przeczek is a Polish writer who has lived in Karviná, the Czech Republic, since he was born in 1936. He is a member of a Polish minority and he has aimed his literary output at its members and at readers in Poland.
Libor Martinek
doaj   +1 more source

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