Results 61 to 70 of about 1,062,147 (264)
Combining osimertinib with the STING agonist ADU‐S100 activates innate and adaptive immunity to overcome the non‐inflamed microenvironment of Egfr‐mutant lung cancer. This combination increases NK and CD8+ T‐cell infiltration, associated with activation of the STING‐IRF3 pathway and local immunogenic cell death.
Jun Nishimura +19 more
wiley +1 more source
Tropical Gothic: Radiance Revisited
Directed by Rachel Perkins in 1998, Radiance is a film that deserves a sequel. The fates of Mae, Cressy and Nona after they head off up the road in Mae's old car is a cinematic mystery that intrigues me more the longer I live in North Queensland, the ...
Allison Craven
doaj +1 more source
The House, the Home and the Housing Question
Housing is a central program in contemporary architectural production. Incorporating civilizing values of 19th century culture, the house arrives in the 20th century at the time notions of private space and domestic comfort come to the fore in Western Culture as values inseparable from the emergence of the family in domestic space: the home.
openaire +3 more sources
We identify USP29 as the only DUB mirroring CA9 expression, a marker of hypoxia and HIF pathway activation associated with PCA aggressiveness. USP29 stabilizes HIF‐1α and HIF‐2α via a noncanonical mechanism that is independent of PHD/pVHL activity yet relies on proteasomal regulation, establishing USP29 as a previously unrecognized regulator of hypoxic
Amelie S Schober +16 more
wiley +1 more source
A house is a building that functions as a residence or residence and a means of family development (Law No. 4 of 1992). Every community needs a house as a necessity. With so many people needing a place to live, house construction often occurs.
Annisa Nur Afifah Kusuma Sayekti +2 more
doaj +1 more source
Loss of proton‐sensing TDAG8 increases tumor progression in mouse models of colon cancer
Loss of the pH‐sensing receptor TDAG8 accelerates colorectal cancer progression in mice. Animals lacking TDAG8 expression had increased tumor growth, DNA damage, and recruitment of tumor‐associated immune cells, including macrophages, neutrophils, and monocytes.
Ermanno Malagola +11 more
wiley +1 more source
The study of the sociability of the old regime takes the house as its main territorial expression. At the same time, the house was the main space of sociability and contact in the city at a time when public and private were not clearly distinguished ...
Romina Zamora
doaj +1 more source
LUNAR is a liver‐specific long noncoding RNA (lncRNA) that is highly expressed in normal liver but becomes epigenetically silenced in hepatocellular carcinoma through promoter hypermethylation. Loss of LUNAR is associated with NOTCH activation, epithelial–mesenchymal transition, and metastasis, whereas restoring LUNAR restrains metastatic progression ...
Se Ha Jang +9 more
wiley +1 more source
Mythological characters of the cultural space in the folklore of the Russian North and Norway (typological aspects)is a comparative analysis of spirits of house that exist in the cultures of both countries. For comparison, we examined different
Наталья Дранникова
doaj +1 more source
Poetic landscapes of Wilhelm Przeczek
Wilhelm Przeczek is a Polish writer who has lived in Karviná, the Czech Republic, since he was born in 1936. He is a member of a Polish minority and he has aimed his literary output at its members and at readers in Poland.
Libor Martinek
doaj +1 more source

