Results 41 to 50 of about 419,416 (300)
CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3
PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh +12 more
wiley +1 more source
In judicial practice, criminal preventive measures attract attention that could be used for better purposes, moving away from their complementary role in per se criminal proceedings and deepening the sensitive border crack between private and societal ...
Bogdan TROFIN +1 more
doaj +1 more source
Interface of gender and culture [PDF]
I greet you in the soothing waters of the Pacific. The birth waters of Hawai’i to the North, island of the dream time, and Aotearoa, to the south. Papua New Guinea to the West and Marquesas to the East.
Tamasese, Kiwi
core +1 more source
EXOSC10, an essential nuclear RNA exosome‐associated 3′‐5′ exoribonuclease, is inhibited by the anticancer drug 5‐fluorouracil (5‐FU), and EXOSC10 depletion increases 5‐FU sensitivity. The colon‐cancer variant EXOSC10S402T, located in a proteolysis motif, is stable and nuclear but nonfunctional in vivo.
Radhika Sain +10 more
wiley +1 more source
Warrantless Arrests in Homes: Another Crisis for the Fourth Amendment [PDF]
This comment addresses the distinction between a forcible entry for an arrest and one for a search. In doing so, the comment looks to the fourth amendment\u27s bifurcated standard for searches and those for arrests. Balancing governmental interests with
O\u27Connor, Darren
core +1 more source
Single‐molecule DNA flow‐stretch assays for high‐throughput DNA–protein interaction studies
We describe an optimised single‐molecule DNA flow‐stretch assay that visualises DNA–protein interactions in real time. Linear DNA fragments are tethered to a surface and stretched by buffer flow for fluorescence imaging. Using λ and φX174 DNA, this protocol enhances reproducibility and accessibility, providing a versatile approach for studying diverse ...
Ayush Kumar Ganguli +8 more
wiley +1 more source
Home Confinement in the United States: The Evolution of Progressive Criminal Justice Reform
Home confinement, also known as house arrest or home detention, first appeared in the United States in the 1970s as a form of pretrial release issued after a defendant's indictment.
Markus Aloyan
doaj
Mulheres-mães selecionadas pelo sistema penal: os desafios do cuidado em prisão domiciliar
Este estudo busca responder quais desafios particulares mulheres-mães em prisão domiciliar enfrentam para viabilizar o cuidado de suas crianças. Partindo da sociologia do cuidado, o artigo apresenta o cuidado como componente do bem-estar social e como um
Amanda Kovalczuk de Oliveira Garcia +1 more
doaj
Palestinians, Israel and the Quartet: Pulling Back from the Brink [PDF]
Throughout years of uprising and Israeli military actions, siege of West Bank cities and President Arafat's de facto house arrest, it was hard to imagine the situation getting worse for Palestinians. It has.
core
YIPFα1A expression is regulated by multilayered molecular mechanisms
YIPFα1A, a five‐pass Golgi protein, is regulated at multiple layers. (1) Rare‐codon enrichment drives translation‐coupled mRNA decay. (2) A proximal 3′‐UTR element stabilizes mRNA. (3) A distal 3′‐UTR element included by alternate poly(A) site usage represses translation, which can be overridden by the proximal 3′‐UTR element.
Tokio Takaji +2 more
wiley +1 more source

