Results 61 to 70 of about 1,353,539 (295)

Genetic attenuation of ALDH1A1 increases metastatic potential and aggressiveness in colorectal cancer

open access: yesMolecular Oncology, EarlyView.
Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova   +25 more
wiley   +1 more source

POGOe: Healthy Ager Life History Project

open access: yesMedEdPORTAL, 2007
This resource trains students how to gather a life history from a “healthy ager,” someone who is defined as being over the age of 60. Students are trained in class and then meet with an assigned older adult to conduct the life history.
Lynn Bickley
doaj   +1 more source

Bringing Primary Care Home: The Medical House Call Program at MedStar Washington Hospital Center [PDF]

open access: yes, 2016
MedStar's program offers round-the-clock access to a care team comprising a geriatrician, nurse practitioner, and social worker. The house calls reveal and address problems that are missed when care is poorly coordinated, enabling team members to ...
Douglas McCarthy   +2 more
core  

Interrogating the immune landscape of microsatellite stable RAS‐mutated colon cancer

open access: yesMolecular Oncology, EarlyView.
COLOSSUS project RAS‐mutated MSS colon cancer study explored transcriptomics and immune cell density by immunohistochemistry (IHC), Immunoscore (IS), ISIC/TuLIS scores, mutation counts, and detected different prevalences but similar microenvironment composition across immune markers with clinical relevance for future immunotherapy combination ...
Rodrigo Dienstmann   +61 more
wiley   +1 more source

Acceptability and feasibility of a comprehensive fall prevention model for independent older adults: A qualitative evaluation

open access: yesInternational Journal of Nursing Studies Advances
Background: Falls amongst the elderly represent a global public health challenge because of their potential to cause illness, death, and reduce the autonomy of this group.
Francisca Marquez-Doren   +4 more
doaj   +1 more source

Locomotion difficulty and need for home care: a cross-sectional study [PDF]

open access: yesRevista de Saúde Pública
OBJECTIVE To investigate home visits by physicians or nurses for consultations and procedures and associated factors in families with people with mobility difficulties and need for home care.
Rogério da Silva Linhares   +5 more
doaj   +1 more source

When duty house calls [PDF]

open access: yesNeurology, 2020
Abstract: A neurologist conducts her first “house call” during the Covid-19 pandemic: the quaint nostalgia of a bygone era and seeming anachronism meet the conveniences of modernity and uncover the timeless qualities of medicine. The phrase “house call” conjures up nostalgia for an era most of us have never experienced, painted with cheerful and ...
openaire   +2 more sources

Complex Care Management Program Overview [PDF]

open access: yes, 2013
This report includes brief updates on various forms of complex care management including: Aetna - Medicare Advantage Embedded Case Management ProgramBrigham and Women's Hospital - Care Management ProgramIndependent Health - Care PartnersIntermountain ...

core  

Keratin 19 as a prognostic marker and contributing factor of metastasis and chemoresistance in high‐grade serous ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch   +13 more
wiley   +1 more source

Antibiofilm activity of a chionodracine‐derived peptide by NMR‐based metabolomics of cell‐free supernatant of Acinetobacter baumannii clinical strains

open access: yesFEBS Open Bio, EarlyView.
KHS‐Cnd peptide is able to impair biofilm formation and disaggregate mature biofilms in Acinetobacter baumannii clinical isolates. Differences in extracellular metabolites reflect changes in biofilm metabolism due to KHS‐Cnd treatment. Among the differentially represented extracellular metabolites upon KHS‐Cnd treatment, the significantly altered ...
Fernando Porcelli   +9 more
wiley   +1 more source

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