Results 61 to 70 of about 1,354,963 (295)
Locomotion difficulty and need for home care: a cross-sectional study [PDF]
Revista de Saúde PúblicaOBJECTIVE To investigate home visits by physicians or nurses for consultations and procedures and associated factors in families with people with mobility difficulties and need for home care.
Rogério da Silva Linhares +5 more
doaj +1 more source
Constitutivism without Normative Thresholds [PDF]
, 2017 Constitutivist accounts in metaethics explain the normative standards in a domain by appealing to the constitutive features of its members. The success of these accounts turns on whether they can explain the connection between normative standards and the
Lindeman, Kathryn
core +2 more sources
ATF4‐mediated stress response as a therapeutic vulnerability in chordoma
Molecular Oncology, EarlyView.We screened 5 chordoma cell lines against 100+ inhibitors of epigenetic and metabolic pathways and kinases and identified halofuginone, a tRNA synthetase inhibitor. Mechanistically halofuginone induces an integrated stress response, with eIF2alpha phosphorylation, activation of ATF4 and its target genes CHOP, ASNS, INHBE leading to cell death ...
Lucia Cottone +11 more
wiley +1 more source
International Journal of Nursing Studies AdvancesBackground: Falls amongst the elderly represent a global public health challenge because of their potential to cause illness, death, and reduce the autonomy of this group.
Francisca Marquez-Doren +4 more
doaj +1 more source
Neutron Shielding Optimization Studies [PDF]
, 2015 The IsoDAR sterile-neutrino search calls for a high neutron flux from a 60 MeV proton beam striking a beryllium target, that flood a sleeve of highly-enriched 7Li, the beta-decay of the resulting 8Li giving the desired neutrinos for the veryshort ...
Alonso, Jose +5 more
core
The contribution of ecological footprinting to planning policy development: using REAP to evaluate policies for sustainable housing construction [PDF]
, 2008 The complexity of the sustainable-development policy goal is such that policy makers are searching for tools to enable them to evaluate and develop policy directions.
Nye, M, Rydin, Y
core +1 more source
Molecular Oncology, EarlyView.Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon +13 more
wiley +1 more source
Neurology, 2020 Abstract: A neurologist conducts her first “house call” during the Covid-19 pandemic: the quaint nostalgia of a bygone era and seeming anachronism meet the conveniences of modernity and uncover the timeless qualities of medicine. The phrase “house call” conjures up nostalgia for an era most of us have never experienced, painted with cheerful and ...
openaire +2 more sources
Therapeutic strategies for MMAE‐resistant bladder cancer through DPP4 inhibition
Molecular Oncology, EarlyView.We established monomethyl auristatin E (MMAE)‐resistant bladder cancer (BC) cell lines by exposure to progressively increasing concentrations of MMAE in vitro. RNA sequencing showed DPP4 expression was increased in MMAE‐resistant BC cells. Both si‐DPP4 and the DPP4 inhibitor sitagliptin suppressed the viability of MMAE‐resistant BC cells.
Gang Li +10 more
wiley +1 more source
Reimagining care: images of aging and creativity in House Calls and Year at Sherbrooke
International Journal of Ageing and Later Life, 2013 This article looks at the relationship between the esthetic and documentary commentaries offered by two National Film Board of Canada (NFB) productions, chosen because they use the documentary form to interpret aging and care in Canada for Canadians ...
Sally Chivers
doaj +1 more source