Results 61 to 70 of about 61,083 (286)

MONITORING FUNCTION OF DPRD TOWARD IMPLEMENTATION OF THE REGIONAL BUDGET REGULATION BULUNGAN REGENCY 2015

open access: yesJournal of Governance and Public Policy, 2018
Based on the problem of research, the aim of this research are to determine and to asses deeply about monitoring function of Regional House of Representatives (DPRD) toward implementation of regional budget (APBD) regulation in Bulungan Regency in the ...
Iskandar Iskandar, Jimmy Nasroen
doaj   +1 more source

Identification of serum protein biomarkers for pre‐cancerous lesions associated with pancreatic ductal adenocarcinoma

open access: yesMolecular Oncology, EarlyView.
This work identified serum proteins associated with pancreatic epithelial neoplasms (PanINs) and early‐stage PDAC. Proteomics screens assessed genetically engineered mice with abundant PanINs, KPC mice (Lox‐STOP‐Lox‐KrasG12D/+ Lox‐STOP‐Lox‐Trp53R172H/+ Pdx1‐Cre) before PDAC development and also early‐stage PDAC patients (n = 31), compared to benign ...
Hannah Mearns   +10 more
wiley   +1 more source

Genetic attenuation of ALDH1A1 increases metastatic potential and aggressiveness in colorectal cancer

open access: yesMolecular Oncology, EarlyView.
Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova   +25 more
wiley   +1 more source

Constitutional Judges: What Powers Does the House of Representatives Have?

open access: yesJurnal Media Hukum
The House of Representatives did not extend the term of constitutional judge Aswanto on September 29, 2022, because Aswanto regularly nullified laws that they passed.
Septi Nur Wijayanti   +4 more
doaj   +1 more source

Interrogating the immune landscape of microsatellite stable RAS‐mutated colon cancer

open access: yesMolecular Oncology, EarlyView.
COLOSSUS project RAS‐mutated MSS colon cancer study explored transcriptomics and immune cell density by immunohistochemistry (IHC), Immunoscore (IS), ISIC/TuLIS scores, mutation counts, and detected different prevalences but similar microenvironment composition across immune markers with clinical relevance for future immunotherapy combination ...
Rodrigo Dienstmann   +61 more
wiley   +1 more source

The nexus clause: A peculiarly Australian obstacle

open access: yesCogent Arts & Humanities, 2018
The nexus between the House of Representatives and the Senate as set out in Section 24 of the Australian Constitution states that the Senate be half the size of the House of Representatives.
Zachary Gorman, Greg Melleuish
doaj   +1 more source

ANALISIS YURIDIS PUTUSAN MAHKAMAH KONSTITUSI NOMOR 16/PUU-XVI/2018 TENTANG PEMBATALAN PERLUASAN KEWENANGAN MAHKAMAH KEHORMATAN DEWAN

open access: yesMasalah-Masalah Hukum, 2019
This research analyzes the Constitutional Court Decision Number 16/PUU-XVI/2018 that has been canceled Article 122 letter l and Article 245 section (1) from the Law Number 2 of 2018.
Yohanes Nafta Irawan   +2 more
doaj   +1 more source

Keratin 19 as a prognostic marker and contributing factor of metastasis and chemoresistance in high‐grade serous ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch   +13 more
wiley   +1 more source

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

open access: yesMolecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric   +10 more
wiley   +1 more source

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