Results 171 to 180 of about 1,360,924 (312)

Effect of chemotherapy on passenger mutations in metastatic colorectal cancer

Molecular Oncology, EarlyView.
Changes in passenger mutation load and predicted immunotherapy response after chemotherapy treatment. Tumor cells rich with passenger mutations have increased sensitivity to chemotherapy. Correlation of passenger mutations with neoantigen load suggests highly mutated clones promote a more effective response to immunotherapy, and therefore, first‐line ...
Marium T. Siddiqui, Matthew A. Cottam, Muhammad Bilal Mirza, Keeli B. Lewis, Kristen K. Ciombor, Mary Kay Washington, Kamran Idrees   +6 more
wiley   +1 more source

The Malaria Vaccine Implementation Programme study area in Ghana: results of a household survey prior to the introduction of the RTS,S/AS01 vaccine. [PDF]

Malar J
Welaga P, Gyan T, Koram K, Hodgson A, Odei-Lartey E, Agbokey F, Gyaase S, Awini E, Adu-Gyasi D, Amenuvegbe GK, Dadzie D, Adam AR, Hammond J, Sarfo A, Nuhu AR, Peprah PT, Twumwaa L, Boateng E, Snell P, Fogelson A, Okine RNA, Hamel MJ, Milligan P, Moore KA, Binka FN, Afari EA, Asante KP.   +26 more
europepmc   +1 more source

Household Size Economies: Malaysian Evidence [PDF]

People live in households with different size and composition and they consume a variety of goods; categorised as private and public goods. With the existence of public goods in the household, doubling the household size need not increase the consumption
Gillis Maclean, Paul Dalziel, Thaiyoong Penny Mok   +2 more
core  

Dual targeting of RET and SRC synergizes in RET fusion‐positive cancer cells

Molecular Oncology, EarlyView.
Despite the strong activity of selective RET tyrosine kinase inhibitors (TKIs), resistance of RET fusion‐positive (RET+) lung cancer and thyroid cancer frequently occurs and is mainly driven by RET‐independent bypass mechanisms. Son et al. show that SRC TKIs significantly inhibit PAK and AKT survival signaling and enhance the efficacy of RET TKIs in ...
Juhyeon Son, Lily L. Remsing Rix, Bin Fang, Eric A. Welsh, Nicole V. Bremer, Valentina Foglizzo, Paola Roa, Nickole Sigcha‐Coello, Yi Liao, Eric B. Haura, Alexander Drilon, John M. Koomen, Emiliano Cocco, Uwe Rix   +13 more
wiley   +1 more source

The cascade of hypertension prevalence, awareness, treatment, and control in urban-poor communities in Accra, Ghana: a population-based household survey. [PDF]

BMC Public Health
Sanuade OA, Baatiema L, Kretchy IA, Okoibhole L, Kushitor SB, Grijalva-Eternod CS, Lule SA, Arhinful D, Koram K, Fottrell E.   +9 more
europepmc   +1 more source

Household waste recycling: national survey evidence from Italy [PDF]

The paper analyses the determinants of household recycling in Italy with particular emphasis on social behaviour. The econometric analysis is based on two waves - 1998 and 2000 - of the Multipurpose Household Survey conducted annually by the Italian ...
Fiorillo, Damiano
core   +1 more source

Molecular characterisation of human penile carcinoma and generation of paired epithelial primary cell lines

Molecular Oncology, EarlyView.
Generation of two normal and tumour (cancerous) paired human cell lines using an established tissue culture technique and their characterisation is described. Cell lines were characterised at cellular, protein, chromosome and gene expression levels and for HPV status.
Simon Broad, Mahmood Hachim, Tom Bertin, Karolina Penderecka, Rifat Hamoudi, Saif Khan, Rui Henrique, Natalie Bergmoser, Manit Arya, Kalle Sipila, Matteo Vietri Rudan, Asif Muneer, Aamir Ahmed   +12 more
wiley   +1 more source

Increase in intimate partner violence during the COVID19 lockdown in uganda: a household survey. [PDF]

BMC Public Health
Kitutu FE, Olum R, Nakamanya SK, Nakisita O, Clarke SE, Hutchinson E.   +5 more
europepmc   +1 more source

Cis‐regulatory and long noncoding RNA alterations in breast cancer – current insights, biomarker utility, and the critical need for functional validation

Molecular Oncology, EarlyView.
The noncoding region of the genome plays a key role in regulating gene expression, and mutations within these regions are capable of altering it. Researchers have identified multiple functional noncoding mutations associated with increased cancer risk in the genome of breast cancer patients.
Arnau Cuy Saqués, Aracele Martinez‐Mendez, John Crown, Alex Eustace   +3 more
wiley   +1 more source

A serological household survey on social determinants of the generalized HIV epidemic in southern Brazil. [PDF]

Sci Rep
Wendland E, Vieira BA, Eidt G, Ikeda MLR, de Souza FMA, Tonini ML, Gaspar PC, Hallal RC, Moherdaui F, Pereira GFM, Bidinotto AB.   +10 more
europepmc   +1 more source