Results 91 to 100 of about 3,653,103 (356)

A critical reflection on intensive pork production with an emphasis on animal health and welfare.

Journal of Animal Science, 2019
The majority of livestock in high-income countries is raised in intensive production systems, with pigs being one of the most important food-producing animals. Worldwide, pork accounts for approximately 35% of all meat production.
D. Maes, J. Dewulf, C. Piñeiro, S. Edwards, I. Kyriazakis   +4 more
semanticscholar   +1 more source

Zukunftsfähige Stallkonzepte für die ökologische Milcherzeugung [PDF]

, 2017
Ensuring high animal welfare standards is one of the objectives of organic farming. The combination of modern housing concepts, proper herd management and good human-animal relationship could be an effective strategy.
Degenkolb, R., Eilers, U., Fegert, D.
core  

CDK11 inhibition induces cytoplasmic p21WAF1 splice variant by p53 stabilisation and SF3B1 inactivation

Molecular Oncology, EarlyView.
CDK11 inhibition stabilises the tumour suppressor p53 and triggers the production of an alternative p21WAF1 splice variant p21L, through the inactivation of the spliceosomal protein SF3B1. Unlike the canonical p21WAF1 protein, p21L is localised in the cytoplasm and has reduced cell cycle‐blocking activity.
Radovan Krejcir, Lukasz Arcimowicz, Lucia Martinkova, Vaclav Hrabal, Filip Zavadil Kokas, Tomas Henek, Martina Kucerikova, Ondrej Bonczek, Pavlina Zatloukalova, Lenka Hernychova, Philip J. Coates, Borivoj Vojtesek, David P. Lane   +12 more
wiley   +1 more source

Vision of Dutch organic dairy farmers on animal health and welfare [PDF]

, 2009
Dutch organic dairy farmers expressed their opinions on animal health and welfare in order to be able to communicate it internally (within the dairy sector) and externally (to consumers).
Bestman, M.W.P., Eijck, I.A.J.M., Smolders, E.A.A.   +2 more
core   +1 more source

Reduced vascular leakage correlates with breast carcinoma T regulatory cell infiltration but not with metastatic propensity

Molecular Oncology, EarlyView.
A mouse model for vascular normalization and a human breast cancer cohort were studied to understand the relationship between vascular leakage and tumor immune suppression. For this, endothelial and immune cell RNAseq, staining for vascular function, and immune cell profiling were employed.
Liqun He, Chiara Testini, Neda Hekmati, Altea Bonello, Aglaia Schiza, Emmanuel Nwadozi, Mia Phillipson, Carina Strell, Michael Welsh   +8 more
wiley   +1 more source

Symposium review: Animal welfare in free-walk systems in Europe.

Journal of Dairy Science, 2020
Providing more space per animal, soft bedding, and free roaming in animal housing systems is widely presumed to be beneficial for the welfare of the animals.
Isabel Blanco-Penedo, W. Ouweltjes, E. Ofner-Schröck, K. Brügemann, U. Emanuelson   +4 more
semanticscholar   +1 more source

Class IIa HDACs forced degradation allows resensitization of oxaliplatin‐resistant FBXW7‐mutated colorectal cancer

Molecular Oncology, EarlyView.
HDAC4 is degraded by the E3 ligase FBXW7. In colorectal cancer, FBXW7 mutations prevent HDAC4 degradation, leading to oxaliplatin resistance. Forced degradation of HDAC4 using a PROTAC compound restores drug sensitivity by resetting the super‐enhancer landscape, reprogramming the epigenetic state of FBXW7‐mutated cells to resemble oxaliplatin ...
Vanessa Tolotto, Nicolò Gualandi, Ylenia Cortolezzis, Raffaella Picco, Monica Colitti, Francesca D'Este, Mariachiara Gani, Wayne W. Hancock, Giovanni Terrosu, Cristina Degrassi, Francesca Agostini, Claudio Brancolini, Luigi E. Xodo, Eros Di Giorgio   +13 more
wiley   +1 more source

Use of location tracking to link egg production with toe pecking injuries, feather quality, body mass in laying hens

Journal of Applied Poultry Research
Summary: The current study sought to validate a proxy for egg laying that could be used within cage-free housing systems towards breeding programs of laying hens.
M.J. Toscano, M. Neuditschko, S.G. Gebhardt-Henrich   +2 more
doaj   +1 more source

Methylation biomarkers can distinguish pleural mesothelioma from healthy pleura and other pleural pathologies

Molecular Oncology, EarlyView.
We developed and validated a DNA methylation–based biomarker panel to distinguish pleural mesothelioma from other pleural conditions. Using the IMPRESS technology, we translated this panel into a clinically applicable assay. The resulting two classifier models demonstrated excellent performance, achieving high AUC values and strong diagnostic accuracy.
Janah Vandenhoeck, Nele De Meulenaere, Thomas Vanpoucke, Joe Ibrahim, Dieter Peeters, Suresh Krishan Yogeswaran, Wen Wen, Paul Van Schil, Jeroen M. H. Hendriks, Jo Raskin, Jan van Meerbeeck, Guy Van Camp, Ken Op de Beeck   +12 more
wiley   +1 more source

Gesundheitserhebung bei Legehennen zur Verbesserung der Tiergesundheit durch Implementierung von Tiergesundheitsplänen [PDF]

, 2007
This study was implemented to improve animal health of laying hens on organic farms. 20 farms were selected and animal health was evaluated. The farmers were inter-viewed about the housing system and management practices.
Goeritz, Mareike, Koopmann, Regine, Müller-Arnke, Ina, Plate, Hans, Rahmann, Gerold, Schumacher, Ulrich   +5 more
core