Results 71 to 80 of about 354,081 (244)

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

open access: yesMolecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Study on Significant Mechanisms of Maintenance Culture Among Public Building Users in Malaysia

open access: yesSHS Web of Conferences, 2014
Malaysia, a country in Asia, is a fast-growing developing country in its construction so as to fulfil the demands of today. Many buildings, infrastructures and facilities were constructed; however, the necessary support required after construction was ...
Binti Rusli Ezzatul Aifa   +2 more
doaj   +1 more source

SOME SPECIFIC FEATURES OF RESOURCE SAVING IN CONSTRUCTION

open access: yesНаука и техника, 2018
The Republic of Belarus possesses a limited number of important natural resources and their conservation is considered as one of the strategic directions for the development of construction industry.
S. N. Osipov   +2 more
doaj   +1 more source

Colorectal cancer‐derived FGF19 is a metabolically active serum biomarker that exerts enteroendocrine effects on mouse liver

open access: yesMolecular Oncology, EarlyView.
Meta‐transcriptome analysis identified FGF19 as a peptide enteroendocrine hormone associated with colorectal cancer prognosis. In vivo xenograft models showed release of FGF19 into the blood at levels that correlated with tumor volumes. Tumoral‐FGF19 altered murine liver metabolism through FGFR4, thereby reducing bile acid synthesis and increasing ...
Jordan M. Beardsley   +5 more
wiley   +1 more source

Structural Component Defects of Low Cost Housing: A Case Study at Taman Bandar Perdana, Sungai Petani, Kedah, Malaysia

open access: yesMATEC Web of Conferences, 2014
Building defects are defined as building or house flaws, or design mistakes, that reduce value and cause dangerous conditions to their occupants. According to the National Building Agency, defect occurrences are caused by poor design, low quality ...
Sulieman M.Z.   +2 more
doaj   +1 more source

Identification of serum protein biomarkers for pre‐cancerous lesions associated with pancreatic ductal adenocarcinoma

open access: yesMolecular Oncology, EarlyView.
This work identified serum proteins associated with pancreatic epithelial neoplasms (PanINs) and early‐stage PDAC. Proteomics screens assessed genetically engineered mice with abundant PanINs, KPC mice (Lox‐STOP‐Lox‐KrasG12D/+ Lox‐STOP‐Lox‐Trp53R172H/+ Pdx1‐Cre) before PDAC development and also early‐stage PDAC patients (n = 31), compared to benign ...
Hannah Mearns   +10 more
wiley   +1 more source

Analysis ofthe level of Permeability and Wayfinding of aRetirement Village: The Case of KampungAdmiralty, Singapore

open access: yesInternational Journal of Built Environment and Sustainability
The dramatic rise in the aging population has become a formidable global phenomenon, especially in developing countries, including Malaysia.
Wai Yee Loh   +3 more
doaj   +1 more source

Investigation of Industrialised Building System Performance in Comparison to Conventional Construction Method

open access: yesMATEC Web of Conferences, 2014
Conventional construction methods are still widely practised, although many researches have indicated that this method is less effective compared to the IBS construction method.
Othuman Mydin M.A.   +2 more
doaj   +1 more source

“Housing Without Housing” en Marruecos [PDF]

open access: yesEntelequia. Revista Interdisciplinar, 2010
Universidad de ...
openaire   +2 more sources

Genetic attenuation of ALDH1A1 increases metastatic potential and aggressiveness in colorectal cancer

open access: yesMolecular Oncology, EarlyView.
Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova   +25 more
wiley   +1 more source

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