Results 41 to 50 of about 18,923,533 (302)

Synergistic perspectives—How single‐molecule biophysics complement biochemical understanding

open access: yesFEBS Letters, EarlyView.
In this review, we discuss how ensemble biochemistry and single‐molecule approaches are complementary, outline commonly used single‐molecule techniques, and illustrate their relevance through two representative case studies: chromatin organization by SMC complexes and pathway choice during DNA double‐strand break repair.
Sara De Bragança   +2 more
wiley   +1 more source

Effect of Cage and Floor Housing Systems on Muscle Fiber Characteristics, Carcass Characteristics, and Meat Quality of Slow-Growing Meat-Type Chickens

open access: yesAgriculture, 2023
This study compared floor (FS) with cage systems (CS) for slow-growing meat-type chickens in terms of muscle fiber characteristics, carcass characteristics, and meat quality.
Yanyan Sun   +5 more
doaj   +1 more source

The Shewanella oneidensis Fic enzyme SoFic targets the switch‐I region of EF‐Tu for AMPylation

open access: yesFEBS Letters, EarlyView.
Fic enzymes mediate diverse post‐translational modifications across all domains of life, including AMPylation. Prokaryotic EF‐Tu can be AMPylated and deAMPylated by the conserved Fic enzyme SoFic. Structural and biochemical approaches were used to characterize the effect of AMPylation on EF‐Tu, SoFic's enzymatic activities, and the enzyme‐target ...
Svenja Runge   +6 more
wiley   +1 more source

Other title: Kansas Housing Resources Corporation press releases, 2016; Other title: Kansas Housing Resources Corporation news releases, 2013

open access: yes, 2023
March 2016; application/pdf; Annual cumulation of 2016 issues$2M in Kansas Home Loan Guarantee funds to help lenders, homeowners finance rural Kansas homes -- Building for the Future: 2022 Annual Report -- Homeowners in need of assistance encouraged to ...
Kansas Housing Resources Corporation.
core  

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

open access: yesMolecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

EFFECT OF DIFFERENT HOUSING SYSTEMS ON THE SERUM IRON AND HAEMOGLOBIN CONTENT IN LARGE WHITE YORKSHIRE PIGS [PDF]

open access: yesJournal of Veterinary and Animal Sciences, 2008
A study was conducted at Livestock Research Station, Kattupakkam to assess the effect of different housing systems viz., intensive, semi-intensive and extensive systems on the serum iron and haemoglobin content in Large White Yorkshire pigs.
M. Pushpalatha   +4 more
doaj  

Stimulator of interferon genes agonist augmented antitumor immunity of osimertinib in Egfr‐mutated lung cancer

open access: yesMolecular Oncology, EarlyView.
Combining osimertinib with the STING agonist ADU‐S100 activates innate and adaptive immunity to overcome the non‐inflamed microenvironment of Egfr‐mutant lung cancer. This combination increases NK and CD8+ T‐cell infiltration, associated with activation of the STING‐IRF3 pathway and local immunogenic cell death.
Jun Nishimura   +19 more
wiley   +1 more source

Other title: Kansas Housing Resources Corporation press releases, 2020; Other title: Kansas Housing Resources Corporation news releases, 2013

open access: yes, 2020
Kansas Housing awards $2.3 million for rural housing development -- In search of a fresh start, and dignity -- Alissa Ice named Director of Housing Development -- Addressing the Need: 2019 Annual Report -- Kansas Housing awards $150,000 to support ...
Kansas Housing Resources Corporation.
core  

USP29‐regulated noncanonical stabilization of the hypoxia‐inducible factor‐α in aggressive prostate cancer

open access: yesMolecular Oncology, EarlyView.
We identify USP29 as the only DUB mirroring CA9 expression, a marker of hypoxia and HIF pathway activation associated with PCA aggressiveness. USP29 stabilizes HIF‐1α and HIF‐2α via a noncanonical mechanism that is independent of PHD/pVHL activity yet relies on proteasomal regulation, establishing USP29 as a previously unrecognized regulator of hypoxic
Amelie S Schober   +16 more
wiley   +1 more source

Loss of proton‐sensing TDAG8 increases tumor progression in mouse models of colon cancer

open access: yesMolecular Oncology, EarlyView.
Loss of the pH‐sensing receptor TDAG8 accelerates colorectal cancer progression in mice. Animals lacking TDAG8 expression had increased tumor growth, DNA damage, and recruitment of tumor‐associated immune cells, including macrophages, neutrophils, and monocytes.
Ermanno Malagola   +11 more
wiley   +1 more source

Home - About - Disclaimer - Privacy