Results 211 to 220 of about 44,748 (258)
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BioEssays, 2005
AbstractIn many bilaterian phyla, appendages are morphological traits that characterise the identity of the various body parts. In pterygote insects, wings are dorsal appendages on the thorax. The famous “bithorax” fly created by Ed Lewis is the emblematic example of the role of Hox genes.1 Now, Tomoyasu et al.,2 using classical genetics, transgenesis ...
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AbstractIn many bilaterian phyla, appendages are morphological traits that characterise the identity of the various body parts. In pterygote insects, wings are dorsal appendages on the thorax. The famous “bithorax” fly created by Ed Lewis is the emblematic example of the role of Hox genes.1 Now, Tomoyasu et al.,2 using classical genetics, transgenesis ...
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The International Journal of Developmental Biology, 1994
During the last few years, the regionalization of the rostral-caudal axis has been extensively studied through treatments with RA and genetic manipulations of Hox-C genes. RA shifts several Hox expression boundaries rostrally, deletes anterior rhombomeres but expands the caudal ones, and induces homeotic transformations in the vertebral column.
A E, Carrasco, S L, López
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During the last few years, the regionalization of the rostral-caudal axis has been extensively studied through treatments with RA and genetic manipulations of Hox-C genes. RA shifts several Hox expression boundaries rostrally, deletes anterior rhombomeres but expands the caudal ones, and induces homeotic transformations in the vertebral column.
A E, Carrasco, S L, López
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2010
Recent years have seen a plethora of ideas and hypotheses, and lots of debate, about the origin and evolution of the Hox gene cluster. Here I will attempt to summarize these hypotheses, identify their strengths and weaknesses and highlight the types of new data that may lead to further resolution of the competing ideas.
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Recent years have seen a plethora of ideas and hypotheses, and lots of debate, about the origin and evolution of the Hox gene cluster. Here I will attempt to summarize these hypotheses, identify their strengths and weaknesses and highlight the types of new data that may lead to further resolution of the competing ideas.
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Science's STKE, 2004
Homeobox (HOX) genes are highly conserved transcriptional regulators that play a central role in development and pattern formation of higher eukaryotes. Genes encoding microRNAs, tiny 22-nucleotide RNAs involved in gene silencing, are found in almost all eukaryotes and have been implicated in a number of important cell and developmental ...
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Homeobox (HOX) genes are highly conserved transcriptional regulators that play a central role in development and pattern formation of higher eukaryotes. Genes encoding microRNAs, tiny 22-nucleotide RNAs involved in gene silencing, are found in almost all eukaryotes and have been implicated in a number of important cell and developmental ...
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Structural studies of geminin-hox and smad-hox complexes
2014Embryonic development is tightly controlled. The clustered genes of the Hox family of homeobox proteins play an important part in regulating this development and also proliferation. They specify embryonic structures along the body axis, and are associated with normal and malignant cell growth.
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Blood, 2005
Comment on Lawrence et al, page [3988][1] In this issue of Blood, Lawrence and colleagues provide strong evidence that HoxA9 plays a key physiologic role in the proliferation of early mouse hematopoietic stem progenitor cells.
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Comment on Lawrence et al, page [3988][1] In this issue of Blood, Lawrence and colleagues provide strong evidence that HoxA9 plays a key physiologic role in the proliferation of early mouse hematopoietic stem progenitor cells.
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