Results 1 to 10 of about 27,788 (178)
Micromanagement of Drosophila Post-Embryonic Development by Hox Genes [PDF]
Journal of Developmental Biology, 2022 Hox genes function early in development to determine regional identity in animals. Consequently, the loss or gain of Hox gene expression can change this identity and cause homeotic transformations.
Alexandra D. Buffry +1 more
doaj +2 more sources
Octopod Hox genes and cephalopod plesiomorphies [PDF]
Scientific Reports, 2023 Few other invertebrates captivate our attention as cephalopods do. Octopods, cuttlefish, and squids amaze with their behavior and sophisticated body plans that belong to the most intriguing among mollusks.
Cristian Camilo Barrera Grijalba +3 more
doaj +2 more sources
Integrated computational analysis reveals HOX genes cluster as oncogenic drivers in head and neck squamous cell carcinoma [PDF]
Scientific Reports, 2022 Alterations in homeobox (HOX) gene expression are involved in the progression of several cancer types including head and neck squamous cell carcinoma (HNSCC). However, regulation of the entire HOX cluster in the pathophysiology of HNSCC is still elusive.
U Sangeetha Shenoy +4 more
doaj +2 more sources
Comparative Hox genes expression within the dimorphic annelid Streblospio benedicti reveals patterning variation during development [PDF]
EvoDevoHox genes are transcriptional regulators that elicit cell positional identity along the anterior–posterior region of the body plan across different lineages of Metazoan. Comparison of Hox gene expression across distinct species reveals their evolutionary
Jose Maria Aguilar-Camacho +2 more
doaj +2 more sources
Homeobox Genes in Cancers: From Carcinogenesis to Recent Therapeutic Intervention
Frontiers in Oncology, 2021 The homeobox (HOX) genes encoding an evolutionarily highly conserved family of homeodomain-containing transcriptional factors are essential for embryogenesis and tumorigenesis.
Yangyang Feng +15 more
doaj +1 more source
Genomic organization and expression demonstrate spatial and temporal Hox gene colinearity in the lophotrochozoan Capitella sp. I. [PDF]
PLoS ONE, 2008 Hox genes define regional identities along the anterior-posterior axis in many animals. In a number of species, Hox genes are clustered in the genome, and the relative order of genes corresponds with position of expression in the body.
Andreas C Fröbius +2 more
doaj +1 more source
PLoS Genetics, 2022 Hox genes encode evolutionarily conserved transcription factors that specify regional identities along the anterior-posterior (A-P) axis. Although some Hox genes are known to regulate the differentiation of certain neurons, to what extent Hox genes are ...
Chaogu Zheng +2 more
doaj +1 more source
Journal of Education, Health and Sport, 2021 The paper analyzes the role of HOX genes in the processes of embryonic development of vertebrates. Based on the analysis, it is concluded that HOX genes are the most important regulators of embryonic development.
Sergey Dolomatov +2 more
doaj +1 more source
GigaByte, 2022 Hox genes and their cofactors are essential developmental genes specifying regional identity in animals. Hox genes have a conserved arrangement in clusters in the same order in which they specify identity along the anterior–posterior axis. A
Teresa D. Shippy +7 more
doaj +1 more source
Pre-bilaterian origins of the Hox cluster and the Hox code: evidence from the sea anemone, Nematostella vectensis. [PDF]
PLoS ONE, 2007 Hox genes were critical to many morphological innovations of bilaterian animals. However, early Hox evolution remains obscure. Phylogenetic, developmental, and genomic analyses on the cnidarian sea anemone Nematostella vectensis challenge recent claims ...
Joseph F Ryan +6 more
doaj +1 more source