Results 11 to 20 of about 27,788 (178)
Journal of Ovarian Research, 2011 The HOX genes are a family of homeodomain-containing transcription factors that determine cellular identity during development. Here we review a number of recent studies showing that HOX genes are strongly expressed in ovarian cancer, and that in some ...
Kelly Zoë L +4 more
doaj +5 more sources
Hox genes and evolution [version 1; referees: 3 approved] [PDF]
F1000Research, 2016 Hox proteins are a deeply conserved group of transcription factors originally defined for their critical roles in governing segmental identity along the antero-posterior (AP) axis in Drosophila.
Steven M. Hrycaj, Deneen M. Wellik
doaj +3 more sources
Onychophoran Hox genes and the evolution of arthropod Hox gene expression [PDF]
Frontiers in Zoology, 2014 Onychophora is a relatively small phylum within Ecdysozoa, and is considered to be the sister group to Arthropoda. Compared to the arthropods, that have radiated into countless divergent forms, the onychophoran body plan is overall comparably simple and does not display much in-phylum variation.
Janssen, Ralf +3 more
openaire +3 more sources
Collinear Hox-Hox interactions are involved in patterning the vertebrate anteroposterior (A-P) axis. [PDF]
PLoS ONE, 2017 Investigating regulation and function of the Hox genes, key regulators of positional identity in the embryo, opened a new vista in developmental biology.
Kongju Zhu +2 more
doaj +1 more source
Hox genes in development and beyond.
Development, 2023 ABSTRACT Hox genes encode evolutionarily conserved transcription factors that are essential for the proper development of bilaterian organisms. Hox genes are unique because they are spatially and temporally regulated during development in a manner that is dictated by their tightly linked genomic organization.
Hubert KA, Wellik DM.
europepmc +3 more sources
Composition and genomic organization of arthropod Hox clusters
EvoDevo, 2016 Background The ancestral arthropod is believed to have had a clustered arrangement of ten Hox genes. Within arthropods, Hox gene mutations result in transformation of segment identities.
Ryan M. Pace +2 more
doaj +1 more source
BMC Genomics, 2023 Background Bryozoans are mostly sessile aquatic colonial invertebrates belonging to the clade Lophotrochozoa, which unites many protostome bilaterian phyla such as molluscs, annelids and brachiopods.
Ahmed J. Saadi +3 more
doaj +1 more source
American Journal of Respiratory Cell and Molecular Biology, 1996 Hox genes are a specific subgroup of homeobox containing genes that are characterized by their structural and functional homology to homeotic genes of the fruit fly Drosophila (1). These genes play important roles in pattern formation along the anterior-posterior axis in the developing embryo in both invertebrates and vertebrates (2).
openaire +2 more sources
Biochemistry and Biophysics Reports, 2021 Homeobox proteins, encoded by HOX genes, are transcriptional factors playing a crucial role in the master regulatory pathway in the cells. Any mutations in HOX genes will affect the expression of its allied proteins. Such mutations were correlated to the
Waseem El-Huneidi +2 more
doaj +1 more source
Reduction of Hox gene expression by histone H1 depletion. [PDF]
PLoS ONE, 2012 The evolutionarily conserved homeotic (Hox) genes are organized in clusters and expressed collinearly to specify body patterning during embryonic development.
Yunzhe Zhang +4 more
doaj +1 more source