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Fast sequence evolution of
BMC Evolutionary Biology, 2006 Background It is expected that genes that are expressed early in development and have a complex expression pattern are under strong purifying selection and thus evolve slowly. Hox genes fulfill these criteria and thus, should have a low evolutionary rate.
Barbadilla Antonio +3 more
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Role of HOX Genes in Stem Cell Differentiation and Cancer
Stem Cells International, 2018 HOX genes encode an evolutionarily conserved set of transcription factors that control how the phenotype of an organism becomes organized during development based on its genetic makeup.
Seema Bhatlekar +2 more
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Two more Posterior Hox genes and Hox cluster dispersal in echinoderms
BMC Evolutionary Biology, 2018 Background Hox genes are key elements in patterning animal development. They are renowned for their, often, clustered organisation in the genome, with supposed mechanistic links between the organisation of the genes and their expression.
Réka Szabó, David E. K. Ferrier
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Cell, 2014 Reference EPFL-ARTICLE-198028doi:10.1016/j.cell.2014.01.060View record in Web of Science Record created on 2014-04-02, modified on 2017-05 ...
Andrey, Guillaume, Duboule, Denis
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There and Back Again: Hox Clusters Use Both DNA Strands
Journal of Developmental Biology, 2021 Bilaterian animals operate the clusters of Hox genes through a rich repertoire of diverse mechanisms. In this review, we will summarize and analyze the accumulated data concerning long non-coding RNAs (lncRNAs) that are transcribed from sense (coding ...
Elena L. Novikova, Milana A. Kulakova
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Hox genes and the phylogeny of the arthropods [PDF]
Current Biology, 2001 The arthropods are the most speciose, and among the most morphologically diverse, of the animal phyla. Their evolution has been the subject of intense research for well over a century, yet the relationships among the four extant arthropod subphyla - chelicerates, crustaceans, hexapods, and myriapods - are still not fully resolved.
Cook, Charles E. +4 more
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Are Hox genes ancestrally involved in axial patterning? Evidence from the hydrozoan Clytia hemisphaerica (Cnidaria). [PDF]
PLoS ONE, 2009 BACKGROUND: The early evolution and diversification of Hox-related genes in eumetazoans has been the subject of conflicting hypotheses concerning the evolutionary conservation of their role in axial patterning and the pre-bilaterian origin of the Hox and
Roxane Chiori +7 more
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Hox gene clusters in the mussel Mytilus coruscus: Implications for bivalves' evolution
Ecological Indicators, 2023 Hox genes encode transcription factors that are crucial regulators of various developmental processes, including patterning of the body axis and differentiation of cells, tissues and organs. They are organized in clusters in a wide range of Metazoans and
Chengrui Yan +8 more
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Duplicated Hox genes in the spider
Frontiers in Zoology, 2007 Background Hox genes are expressed in specific domains along the anterior posterior body axis and define the regional identity. In most animals these genes are organized in a single cluster in the genome and the order of the genes in the cluster is ...
Schoppmeier Michael +3 more
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Zoological Letters, 2017 Background Hox gene clusters with at least 13 paralog group (PG) members are common in vertebrate genomes and in that of amphioxus. Ascidians, which belong to the subphylum Tunicata (Urochordata), are phylogenetically positioned between vertebrates and ...
Yuka Sekigami +7 more
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