Results 41 to 50 of about 27,788 (178)
Frontiers in Cell and Developmental Biology, 2021 Body axial patterning develops via a rostral-to-caudal sequence and relies on the temporal colinear activation of Hox genes. However, the underlying mechanism of Hox gene temporal colinear activation remains largely elusive.
Feng Zhang +12 more
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Drosophila male genitalia rotation depends on permissive remodeling of the posterior abdomen
Developmental Dynamics, EarlyView.Abstract Background One of the most characteristic morphogenetic processes in Drosophila is the 360° rotation of the male pupal genital disc. This movement is driven by the myosin Myo1D, whose expression in the genital disc is controlled by the Hox gene Abdominal‐B (Abd‐B).
Nuria Prieto +6 more
wiley +1 more source
An Overview of Hox Genes in Lophotrochozoa: Evolution and Functionality
Journal of Developmental Biology, 2016 Hox genes are regulators of animal embryonic development. Changes in the number and sequence of Hox genes as well as in their expression patterns have been related to the evolution of the body plan.
Marco Barucca +2 more
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Developmental Dynamics, EarlyView.Abstract The sea anemone, Nematostella vectensis, has been used as a model organism in developmental biology studies for many years. This estuarine species has the notable capacity to regenerate its full body plan from small pieces throughout life. Nematostella have been described as having a great degree of cellular plasticity.
Patrick A. Lewis +3 more
wiley +1 more source
Extensive polycistronism and antisense transcription in the mammalian Hox clusters.
PLoS ONE, 2007 The Hox clusters play a crucial role in body patterning during animal development. They encode both Hox transcription factor and micro-RNA genes that are activated in a precise temporal and spatial sequence that follows their chromosomal order.
Gaëll Mainguy +4 more
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BMC Evolutionary Biology, 2010 Background Hox and the closely-related ParaHox genes, which emerged prior to the divergence between cnidarians and bilaterians, are the most well-known members of the ancient genetic toolkit that controls embryonic development across all metazoans ...
Ledent Valérie +3 more
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Transcriptional Regulation and Implications for Controlling Hox Gene Expression
Journal of Developmental Biology, 2022 Hox genes play key roles in axial patterning and regulating the regional identity of cells and tissues in a wide variety of animals from invertebrates to vertebrates.
Zainab Afzal, Robb Krumlauf
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Reduced H3K27me3 leads to abnormal Hox gene expression in neural tube defects
Epigenetics & Chromatin, 2019 Background Neural tube defects (NTDs) are severe, common birth defects that result from failure of normal neural tube closure during early embryogenesis. Accumulating strong evidence indicates that genetic factors contribute to NTDs etiology, among them,
Juan Yu +10 more
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Anticancer potential of berberine: Molecular pathways and current clinical trial perspectives
JSFA reports, EarlyView.Abstract Cancer is constantly rising mortality rates due to its late prognosis, poor management, and expensive treatment. Multi‐sectoral approaches for cancer management include hygienic practices, synthetic drug exploitation, radiation therapy, and diet modifications.
Muhammad Maaz +10 more
wiley +1 more source
Hox genes are not always Colinear [PDF]
International Journal of Biological Sciences, 2006 The deuterostomes are the clade of animals for which we have the most detailed understanding of Hox cluster organisation. With the Hox cluster of amphioxus (Branchiostoma floridae) we have the best prototypical, least derived Hox cluster for the group, whilst the urochordates present us with some of the most highly derived and disintegrated clusters ...
Ana Sara, Monteiro, David E K, Ferrier
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