Results 1 to 10 of about 44,748 (258)

Characterization of the Caudal Ventral Tubercle in the Sixth Cervical Vertebra in Modern Equus ferus caballus

Animals, 2023
This study examined the anomalous variations of the ventral process of C6 in modern E. ferus caballus. The aim was to provide an incremental grading protocol measuring the absence of the caudal ventral tubercle (CVT) in this ventral process. The findings
Sharon May-Davis, Diane Dzingle, Elle Saber, Pamela Blades Eckelbarger   +3 more
doaj   +1 more source

Homeotic Genes: Clustering, Modularity, and Diversity

Frontiers in Cell and Developmental Biology, 2021
Hox genes code for transcription factors and are evolutionarily conserved. They regulate a plethora of downstream targets to define the anterior-posterior (AP) body axis of a developing bilaterian embryo.
Nikhil Hajirnis, Rakesh K. Mishra, Rakesh K. Mishra, Rakesh K. Mishra   +3 more
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Dual functionality of O-GlcNAc transferase is required for Drosophila development [PDF]

Open Biology, 2015
Post-translational modification of intracellular proteins with O-linked N-acetylglucosamine (O-GlcNAc) catalysed by O-GlcNAc transferase (OGT) has been linked to regulation of diverse cellular functions.
Daniel Mariappa, Xiaowei Zheng, Marianne Schimpl, Olawale Raimi, Andrew T. Ferenbach, H.-Arno J. Müller, Daan M. F. van Aalten   +6 more
doaj   +1 more source

Elevated Hoxb5b Expands Vagal Neural Crest Pool and Blocks Enteric Neuronal Development in Zebrafish

Frontiers in Cell and Developmental Biology, 2022
Neural crest cells (NCCs) are a migratory, transient, and multipotent stem cell population essential to vertebrate embryonic development, contributing to numerous cell lineages in the adult organism.
Aubrey G. A. Howard, Aaron C. Nguyen, Joshua Tworig, Priya Ravisankar, Priya Ravisankar, Eileen W. Singleton, Can Li, Grayson Kotzur, Joshua S. Waxman, Rosa A. Uribe   +9 more
doaj   +1 more source

The Effect of Forbush Decreases on the Polar-Night HOx Concentration Affecting Stratospheric Ozone

Frontiers in Earth Science, 2021
It is well-known that energetic particle precipitations during solar proton events increase ionization rates in the middle atmosphere enhancing the production of hydrogen oxide radicals (HOx) involved in the catalytic ozone destruction cycle.
Irina Mironova, Irina Mironova, Arseniy Karagodin-Doyennel, Arseniy Karagodin-Doyennel, Eugene Rozanov, Eugene Rozanov   +5 more
doaj   +1 more source

Pan-Cancer Genome-Wide DNA Methylation Analyses Revealed That Hypermethylation Influences 3D Architecture and Gene Expression Dysregulation in HOXA Locus During Carcinogenesis of Cancers

Frontiers in Cell and Developmental Biology, 2021
DNA methylation dysregulation during carcinogenesis has been widely discussed in recent years. However, the pan-cancer DNA methylation biomarkers and corresponding biological mechanisms were seldom investigated.
Gang Liu, Zhenhao Liu, Zhenhao Liu, Xiaomeng Sun, Xiaoqiong Xia, Yunhe Liu, Lei Liu   +6 more
doaj   +1 more source

Genome-Wide Binding of Posterior HOXA/D Transcription Factors Reveals Subgrouping and Association with CTCF. [PDF]

PLoS Genetics, 2017
Homeotic genes code for key transcription factors (HOX-TFs) that pattern the animal body plan. During embryonic development, Hox genes are expressed in overlapping patterns and function in a partially redundant manner.
Ivana Jerković, Daniel M Ibrahim, Guillaume Andrey, Stefan Haas, Peter Hansen, Catrin Janetzki, Irene González Navarrete, Peter N Robinson, Jochen Hecht, Stefan Mundlos   +9 more
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The rapid variation of Hox clusters reveals a clear evolutionary path in a crucian carp-like homodiploid fish lineage

Reproduction and Breeding, 2021
The surprising variation in the number of Hox clusters and genome structure in ray-finned fish lineages reflects the history of duplications and subsequent lineage-specific gene loss.
Shi Wang, Qilong Liu, Xuexue Huang, Conghui Yang, Lan Chen, Mei Han, Yuqin Shu, Min Wang, Wuhui Li, Fangzhou Hu, Ming Wen, Kaikun Luo, Yude Wang, Rong Zhou, Chun Zhang, Min Tao, Rurong Zhao, Chenchen Tang, Shaojun Liu   +18 more
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Genomic organization and expression demonstrate spatial and temporal Hox gene colinearity in the lophotrochozoan Capitella sp. I. [PDF]

PLoS ONE, 2008
Hox genes define regional identities along the anterior-posterior axis in many animals. In a number of species, Hox genes are clustered in the genome, and the relative order of genes corresponds with position of expression in the body.
Andreas C Fröbius, David Q Matus, Elaine C Seaver   +2 more
doaj   +1 more source

Homeobox Genes in Cancers: From Carcinogenesis to Recent Therapeutic Intervention

Frontiers in Oncology, 2021
The homeobox (HOX) genes encoding an evolutionarily highly conserved family of homeodomain-containing transcriptional factors are essential for embryogenesis and tumorigenesis.
Yangyang Feng, Yangyang Feng, Tongyue Zhang, Tongyue Zhang, Yijun Wang, Yijun Wang, Meng Xie, Meng Xie, Xiaoyu Ji, Xiaoyu Ji, Xiangyuan Luo, Xiangyuan Luo, Wenjie Huang, Wenjie Huang, Limin Xia, Limin Xia   +15 more
doaj   +1 more source