Results 41 to 50 of about 44,748 (258)
PLoS Genetics, 2022 Hox genes encode evolutionarily conserved transcription factors that specify regional identities along the anterior-posterior (A-P) axis. Although some Hox genes are known to regulate the differentiation of certain neurons, to what extent Hox genes are ...
Chaogu Zheng +2 more
doaj +1 more source
Nuclear re-organisation of the Hoxb complex during mouse embryonic development [PDF]
, 2005 The spatial and temporal co-linear expression of Hox genes during development is an exquisite example of programmed gene expression. The precise mechanisms underpinning this are not known.
Kirstie A. Lawson +7 more
core +1 more source
Improving Hox protein classification across the major model organisms.
PLoS ONE, 2010 The family of Hox-proteins has been a major focus of research for over 30 years. Hox-proteins are crucial to the correct development of bilateral organisms, however, some uncertainty remains as to which Hox-proteins are functionally equivalent across ...
Stefanie D Hueber +3 more
doaj +1 more source
Zoological Letters, 2017 Background Hox gene clusters with at least 13 paralog group (PG) members are common in vertebrate genomes and in that of amphioxus. Ascidians, which belong to the subphylum Tunicata (Urochordata), are phylogenetically positioned between vertebrates and ...
Yuka Sekigami +7 more
doaj +1 more source
The labial gene is required to terminate proliferation of identified neuroblasts in postembryonic development of the Drosophila brain [PDF]
, 2012 The developing brain of Drosophila has become a useful model for studying the molecular genetic mechanisms that give rise to the complex neuronal arrays that characterize higher brains in other animals including mammals.
Reichert, H. +8 more
core +1 more source
Reduction of Hox gene expression by histone H1 depletion. [PDF]
PLoS ONE, 2012 The evolutionarily conserved homeotic (Hox) genes are organized in clusters and expressed collinearly to specify body patterning during embryonic development.
Yunzhe Zhang +4 more
doaj +1 more source
Advanced Science, EarlyView.HOXC11 drives colorectal cancer progression by transcriptionally activating CAMK2A, which triggers NF‐κB–dependent CXCL5 upregulation. CXCL5–CXCR2 signaling further reinforces HOXC11 expression through the ERK1/2–SP1 axis, forming a prometastatic positive feedback loop that is effectively disrupted by combined CAMK2A and CXCR2 inhibition.
Qingyang Sun +12 more
wiley +1 more source
Hox-cluster genes in the spinocerebellar system
, 2017 The Hox-cluster genes are a family of 39 transcription-factor genes and several micro (mi)RNAs, spread across four genomic clusters. These genes are known for their role in patterning along the anterior-posterior (A-P) axis in several vertebrate tissues,
Coughlan, Eamon (3776812)
core +1 more source
Interface‐Enhanced Electrochemical Epoxidation Over a Core‐Shell Nanozeolite TS‐1@Mn‐N‐C Catalyst
Advanced Science, EarlyView.Core–shell interface of TS‐1@Mn‐N‐C enables in situ generation of high‐concentration H2O2 and its spatially confined activation toward epoxidation‐active η‐Ti‐OOH species, leading to highly efficient and continuous electrochemical epoxidation. The work successfully addresses the key challenge of inefficient mass transfer and slow kinetics caused by ...
Wenbiao Zhang +7 more
wiley +1 more source
Extensive polycistronism and antisense transcription in the mammalian Hox clusters.
PLoS ONE, 2007 The Hox clusters play a crucial role in body patterning during animal development. They encode both Hox transcription factor and micro-RNA genes that are activated in a precise temporal and spatial sequence that follows their chromosomal order.
Gaëll Mainguy +4 more
doaj +1 more source