Results 51 to 60 of about 44,748 (258)

Human HOX Proteins Use Diverse and Context-Dependent Motifs to Interact with TALE Class Cofactors

open access: yesCell Reports, 2018
Summary: HOX proteins achieve numerous functions by interacting with the TALE class PBX and MEIS cofactors. In contrast to this established partnership in development and disease, how HOX proteins could interact with PBX and MEIS remains unclear.
Amélie Dard   +7 more
doaj   +1 more source

Sacral Neural Crest‐Derived Extracellular Vesicles Promote Pelvic Ganglion Repair Through Anti‐Pyroptotic Effects Involving ANXA1–FPR2 Signaling

open access: yesAdvanced Science, EarlyView.
Extracellular vesicles derived from human pluripotent stem cell‐derived sacral neural crest cells promote repair of injured major pelvic ganglia and improve colorectal function. These vesicles reduce oxidative stress and pyroptosis, with ANXA1–FPR2 signaling contributing to their protective effects, and show a favorable therapeutic profile compared ...
Ting Yang   +11 more
wiley   +1 more source

SnapShot: Hox Gene Regulation

open access: yesCell, 2014
Reference EPFL-ARTICLE-198028doi:10.1016/j.cell.2014.01.060View record in Web of Science Record created on 2014-04-02, modified on 2017-05 ...
Andrey, Guillaume, Duboule, Denis
openaire   +3 more sources

Phosphonium Ionic Liquids for Electrochemical Energy Storage: Structure–Property–Interphase Relationships and Design Rule

open access: yesAdvanced Science, EarlyView.
Phosphonium ionic liquids offer a versatile platform for safer and more durable energy storage. This Review connects cation–anion structure with solvation, ion transport, electrochemical stability, and interphase formation across diverse battery chemistries.
Amir Haghipour   +7 more
wiley   +1 more source

Coordination of Hox identity between germ layers along the anterior-to-posterior axis of the vertebrate embryo [PDF]

open access: yes, 2010
During early embryonic development, a relatively undifferentiated mass of cells is shaped into a complex and morphologically differentiated embryo. This is achieved by a series of coordinated cell movements that end up in the formation of the three ...
Lloret Vilaspasa, F.
core  

Hox Targets and Cellular Functions [PDF]

open access: yesScientifica, 2013
Hox genes are a group of genes that specify structures along the anteroposterior axis in bilaterians. Although in many cases they do so by modifying a homologous structure with a different (or no) Hox input, there are also examples of Hox genes constructing new organs with no homology in other regions of the body.
openaire   +4 more sources

Chromosomal Abnormalities, Drug Sensitivity and Resistance in Hematological Malignancies: A Comprehensive Overview by the Francophone Group of Hematological Cytogenetics (GFCH)

open access: yesAmerican Journal of Hematology, EarlyView.
ABSTRACT Chromosomal abnormalities have a major clinical impact on hematological malignancies, particularly with regard to treatment strategies. To preserve and consolidate fundamental knowledge in this rapidly evolving field, the Francophone Group of Hematological Cytogenetics (Groupe Francophone de Cytogénétique Hématologique, GFCH) conducted a ...
Florence Nguyen‐Khac   +16 more
wiley   +1 more source

Comparison of mouse and human HOX-4 complexes defines conserved sequences involved in the regulation of Hox-4.4

open access: yes, 1992
We have cloned and sequenced, in both mouse and human, regions of the HOX-4 complex which contain two Abd-B like genes, Hox-4.4 and Hox-4.5 (HOX4C and HOX4D in human, respectively).
Burki K.   +11 more
core   +2 more sources

Molecular Characterization of HOXA2 and HOXA3 Binding Properties

open access: yesJournal of Developmental Biology, 2021
The highly conserved HOX homeodomain (HD) transcription factors (TFs) establish the identity of different body parts along the antero–posterior axis of bilaterian animals.
Joshua Mallen   +5 more
doaj   +1 more source

Features of the ancestral bilaterian inferred from Platynereis dumerilii ParaHox genes [PDF]

open access: yes, 2009
Background The ParaHox gene cluster is the evolutionary sister to the Hox cluster. Whilst the role of the Hox cluster in patterning the anterior-posterior axis of bilaterian animals is well established, and the organisation of vertebrate Hox clusters is ...
Segurens Béatrice   +47 more
core   +1 more source

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