Results 1 to 10 of about 339,718 (373)
Brain Science, 2021 The hypothalamic-pituitary-adrenal (HPA) axis is involved in the pathophysiology of many neuropsychiatric disorders. Increased HPA axis activity can be observed during chronic stress, which plays a key role in the pathophysiology of depression ...
J. Mikulska +3 more
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The HPA Axis as Target for Depression
Current Neuropharmacology, 2023 Major depressive disorder (MDD) is a stress-related mental disorder with a lifetime prevalence of 20% and, thus, is one of the most prevalent mental health disorders worldwide.
A. Menke
semanticscholar +1 more source
Childhood Trauma, the HPA Axis and Psychiatric Illnesses: A Targeted Literature Synthesis
Frontiers in Psychiatry, 2022 Studies of early life stress (ELS) demonstrate the long-lasting effects of acute and chronic stress on developmental trajectories. Such experiences can become biologically consolidated, creating individual vulnerability to psychological and psychiatric ...
F. Murphy +11 more
semanticscholar +1 more source
Stresses, 2022 Test anxiety may be a contributing factor to low-performing examination scores among students. There can be numerous physiological responses in the body that lead to test anxiety. One is the body’s response to stress, which activates the brain to release
Jenalee A. Hinds, E. R. Sánchez
semanticscholar +1 more source
Stress and Brain, 2023 Motor neuron diseases (MND) are a group of rare neurodegenerative diseases that significantly affect the survival of patients. The disease progresses rapidly, and currently, there is no cure for MND.
Chenyang Lu, Xingshun Xu
doaj +1 more source
The Role of HPA Axis and Allopregnanolone on the Neurobiology of Major Depressive Disorders and PTSD
International Journal of Molecular Sciences, 2021 Under stressful conditions, the hypothalamic-pituitary-adrenal (HPA) axis acts to promote transitory physiological adaptations that are often resolved after the stressful stimulus is no longer present. In addition to corticosteroids (e.g., cortisol), the
F. B. Almeida, G. Pinna, H. Barros
semanticscholar +1 more source
Zhongguo shuxue zazhi, 2022 Objective To establish a platelet donor database with HPA and HLA high resolution results in Hefei area, and to analyze the appropriate pool capacity, so as to provide support for patients with immune PTR transfusion difficulties.
Nana ZHAO +5 more
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Онкогематология, 2022 Purpose: to study influence of platelet antigens system (HPA — Human Platelet Antigens) differences between donor and recipient on neutropenia and trombocytopenia duration after hematopoietic stem cells transplantation (HSCT).Materials and methods: 40 ...
L. L. Golovkina, R. M. Kutyina
doaj +1 more source
Polymorphisms of the human platelet alloantigens HPA‐1, HPA‐2, HPA‐3, and HPA‐4 in ischemic stroke [PDF]
American Journal of Hematology, 2008 AbstractPolymorphism in human platelet antigen (HPA)‐1 and HPA‐3 (GPIIb/IIIa), HPA‐2 (GPIb/IX), HPA‐4 (GPIIIa), and HPA‐5 (GPIa/IIa) was investigated in 329 stroke patients and 444 matched control subjects. HPA genotyping was done by PCR‐SSP method. Lower HPA‐1a (P< 0.001) and higher HPA‐1b (P< 0.001) allele frequencies were seen in patients than
Sarra, Saidi +5 more
openaire +2 more sources
Pharmacological Treatment of Anxiety Disorders: The Role of the HPA Axis
Frontiers in Psychiatry, 2020 Stress in general, and early life stress in particular, has been associated with the development of anxiety and mood disorders. The molecular, biological and psychological links between stress exposure and the pathogenesis of anxiety and mood disorders ...
G. E. Tafet, C. Nemeroff
semanticscholar +1 more source